The development and validation of prognostic models for overall survival in the presence of missing data in the training dataset: a strategy with a detailed example

por Royle, Kara-Louise, Cairns, David A.
Publicado 2021

How is overall survival assessed in randomised clinical trials in cancer and are subsequent treatment lines considered? A systematic review

por Royle, Kara-Louise, Meads, David, Visser-Rogers, Jennifer K., White, Ian R., Cairns, David A.
Publicado 2023

Integrated multi-level quality control for proteomic profiling studies using mass spectrometry

por Cairns, David A, Perkins, David N, Stanley, Anthea J, Thompson, Douglas, Barrett, Jennifer H, Selby, Peter J, Banks, Rosamonde E
Publicado 2008

Initial Development and Validation of a Novel Extraction Method for Quantitative Mining of the Formalin-Fixed, Paraffin-Embedded Tissue Proteome for Biomarker Investigations

por Nirmalan, Niroshini J., Hughes, Christopher, Peng, Jianhe, McKenna, Therese, Langridge, James, Cairns, David A., Harnden, Patricia, Selby, Peter J., Banks, Rosamonde E.
Publicado 2010

An analysis of the impact of pre‐analytical factors on the urine proteome: Sample processing time, temperature, and proteolysis

por Hepburn, Sophie, Cairns, David A., Jackson, David, Craven, Rachel A., Riley, Beverley, Hutchinson, Michelle, Wood, Steven, Smith, Matthew Welberry, Thompson, Douglas, Banks, Rosamonde E.
Publicado 2015

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth

por Mihailovich, Marija, Bremang, Michael, Spadotto, Valeria, Musiani, Daniele, Vitale, Elena, Varano, Gabriele, Zambelli, Federico, Mancuso, Francesco M., Cairns, David A., Pavesi, Giulio, Casola, Stefano, Bonaldi, Tiziana
Publicado 2015

A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses

por Smith, Matthew P Welberry, Wood, Steven L, Zougman, Alexandre, Ho, Jenny T C, Peng, Jianhe, Jackson, David, Cairns, David A, Lewington, Andrew J P, Selby, Peter J, Banks, Rosamonde E
Publicado 2011

NuMA Overexpression in Epithelial Ovarian Cancer

por Brüning-Richardson, Anke, Bond, Jaqueline, Alsiary, Rawiah, Richardson, Julie, Cairns, David A., McCormac, Luci, Hutson, Richard, Burns, Philip A., Wilkinson, Nafisa, Hall, Geoff D., Morrison, Ewan E., Bell, Sandra M.
Publicado 2012

Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised stu...

por Royle, Kara‐Louise, Gregory, Walter M., Cairns, David A., Bell, Sue E., Cook, Gordon, Owen, Roger G., Drayson, Mark T., Davies, Faith E., Jackson, Graham H., Morgan, Gareth J., Child, J. Anthony
Publicado 2018

Optimising pacemaker therapy and medical therapy in pacemaker patients for heart failure: protocol for the OPT-PACE randomised controlled trial

por Paton, Maria F, Gierula, John, Jamil, Haqeel A, Lowry, Judith E, Byrom, Rowena, Gillott, Richard G, Chumun, Hemant, Cubbon, Richard M, Cairns, David A, Stocken, Deborah D, Kearney, Mark T, Witte, Klaus K
Publicado 2019

Personalised reprogramming to prevent progressive pacemaker-related left ventricular dysfunction: A phase II randomised, controlled clinical trial

por Paton, Maria F., Gierula, John, Lowry, Judith E., Cairns, David A., Bose Rosling, Kieran, Cole, Charlotte A., McGinlay, Melanie, Straw, Sam, Byrom, Rowena, Cubbon, Richard M., Kearney, Mark T., Witte, Klaus K.
Publicado 2021

Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation

por Welberry Smith, Matthew P, Zougman, Alexandre, Cairns, David A, Wilson, Michelle, Wind, Tobias, Wood, Steven L, Thompson, Douglas, Messenger, Michael P, Mooney, Andrew, Selby, Peter J, Lewington, Andrew J P, Banks, Rosamonde E
Publicado 2013

The role of ixazomib as an augmented conditioning therapy in salvage autologous stem cell transplant (ASCT) and as a post-ASCT consolidation and maintenance strategy in patients wi...

por Striha, Alina, Ashcroft, A. John, Hockaday, Anna, Cairns, David A., Boardman, Karen, Jacques, Gwen, Williams, Cathy, Snowden, John A., Garg, Mamta, Cavenagh, Jamie, Yong, Kwee, Drayson, Mark T., Owen, Roger, Cook, Mark, Cook, Gordon
Publicado 2018

Association of genetic variants with patient reported quality of life and pain experience in patients in the UK NCRI Myeloma X Relapse [Intensive]) trial; an exploratory study

por Snowden, John A., Ahmedzai, Sam H., Cox, Angela, Cairns, David A., Ashcroft, A. John, Williams, Cathy, Cavenagh, Jamie D., Hockaday, Anna, Brown, Julia M., Brock, Ian W., Morris, Treen C. M., Cook, Gordon
Publicado 2022

CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment

por Westbrook, Jules A., Cairns, David A., Peng, Jianhe, Speirs, Valerie, Hanby, Andrew M., Holen, Ingunn, Wood, Steven L., Ottewell, Penelope D., Marshall, Helen, Banks, Rosamonde E., Selby, Peter J., Coleman, Robert E., Brown, Janet E.
Publicado 2016

Performance of 2014 NICE defibrillator implantation guidelines in heart failure risk stratification

por Cubbon, Richard M, Witte, Klaus K, Kearney, Lorraine C, Gierula, John, Byrom, Rowenna, Paton, Maria, Sengupta, Anshuman, Patel, Peysh A, MN Walker, Andrew, Cairns, David A, Rajwani, Adil, Hall, Alistair S, Sapsford, Robert J, Kearney, Mark T
Publicado 2016

A clinical prediction model for outcome and therapy delivery in transplant-ineligible patients with myeloma (UK Myeloma Research Alliance Risk Profile): a development and validatio...

por Cook, Gordon, Royle, Kara-Louise, Pawlyn, Charlotte, Hockaday, Anna, Shah, Vallari, Kaiser, Martin F, Brown, Sarah R, Gregory, Walter M, Child, J Anthony, Davies, Faith E, Morgan, Gareth J, Cairns, David A, Jackson, Graham H
Publicado 2019

Autologous stem cell transplantation is safe and effective for fit, older myeloma patients: exploratory results from the Myeloma XI trial

por Pawlyn, Charlotte, Cairns, David A., Menzies, Tom, Jones, John R., Jenner, Matthew W., Cook, Gordon, Boyd, Kevin D., Drayson, Mark T., Kaiser, Martin F., Owen, Roger G., Gregory, Walter, Morgan, Gareth J., Jackson, Graham H., Davies, Faith E.
Publicado 2020

How to Simplify the Evaluation of Newly Introduced Chemotherapeutic Interventions in Myeloma

por Morris, Treen Carson Michael, Drake, Mary B., Kettle, Paul J., McGuigan, Tracey, Leahy, Maeve, O’Dwyer, Michael, Enright, Helen, O’Shea, Tanya, Popat, Rakesh, Oakervee, Heather E., Yong, Kwee, Cavenagh, Jamie D., Cairns, David A., Alvarez-Iglesias, Alberto, Cook, Gordon
Publicado 2021

Maintenance lenalidomide in newly diagnosed transplant eligible and non-eligible myeloma patients; profiling second primary malignancies in 4358 patients treated in the Myeloma XI...

por Jones, John R., Cairns, David A., Menzies, Tom, Pawlyn, Charlotte, Davies, Faith E., Sigsworth, Rachel, Brioli, Annamaria, Jenner, Matthew W., Kaiser, Martin F., Olivier, Catherine, Reed, Molly, Drayson, Mark T., Owen, Roger G., Boyd, Kevin D., Cook, Gordon, Morgan, Gareth J., Jackson, Graham H.
Publicado 2023