Principled multi-omic analysis reveals gene regulatory mechanisms of phenotype variation

por Hanson, Casey, Cairns, Junmei, Wang, Liewei, Sinha, Saurabh
Publicado 2018

Bora Downregulation Results in Radioresistance by Promoting Repair of Double Strand Breaks

por Cairns, Junmei, Peng, Yi, Yee, Vivien C., Lou, Zhenkun, Wang, Liewei
Publicado 2015

Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance

por Emad, Amin, Cairns, Junmei, Kalari, Krishna R., Wang, Liewei, Sinha, Saurabh
Publicado 2017

Identification of pathways associated with chemosensitivity through network embedding

por Wang, Sheng, Huang, Edward, Cairns, Junmei, Peng, Jian, Wang, Liewei, Sinha, Saurabh
Publicado 2019

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1

por Cairns, Junmei, Ingle, James N., Wickerham, Lawrence D., Weinshilboum, Richard, Liu, Mohan, Wang, Liewei
Publicado 2017

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation

por Cairns, Junmei, Fridley, Brooke L, Jenkins, Gregory D, Zhuang, Yongxian, Yu, Jia, Wang, Liewei
Publicado 2018

CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer

por Cairns, Junmei, Ly, Reynold C, Niu, Nifang, Kalari, Krishna R, Carlson, Erin E, Wang, Liewei
Publicado 2020

A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes

por Cairns, Junmei, Ung, Choong Yong, da Rocha, Edroaldo Lummertz, Zhang, Cheng, Correia, Cristina, Weinshilboum, Richard, Wang, Liewei, Li, Hu
Publicado 2016

Testis- specific Y-encoded- like protein 1 and cholesterol metabolism: Regulation of CYP1B1 expression through Wnt signaling

por Zhu, Xiujuan, Gao, Huanyao, Qin, Sisi, Liu, Duan, Cairns, Junmei, Gu, Yayun, Yu, Jia, Weinshilboum, Richard M., Wang, Liewei
Publicado 2022

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

por Cairns, Junmei, Ingle, James N., Kalari, Krishna R., Shepherd, Lois E., Kubo, Michiaki, Goetz, Matthew P., Weinshilboum, Richard M., Wang, Liewei
Publicado 2019

Considerations for automated machine learning in clinical metabolic profiling: Altered homocysteine plasma concentration associated with metformin exposure

por Orlenko, Alena, Moore, Jason H., Orzechowski, Patryk, Olson, Randal S., Cairns, Junmei, Caraballo, Pedro J., Weinshilboum, Richard M., Wang, Liewei, Breitenstein, Matthew K.
Publicado 2018

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer

por Athreya, Arjun P., Kalari, Krishna R., Cairns, Junmei, Gaglio, Alan J., Wills, Quin F., Niu, Nifang, Weinshilboum, Richard, Iyer, Ravishankar K., Wang, Liewei
Publicado 2017

Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform

por Lanz, Henriette L., Saleh, Anthony, Kramer, Bart, Cairns, Junmei, Ng, Chee Ping, Yu, Jia, Trietsch, Sebastiaan J., Hankemeier, Thomas, Joore, Jos, Vulto, Paul, Weinshilboum, Richard, Wang, Liewei
Publicado 2017

Interaction Between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early‐Stage Breast Cancer

por Cairns, Junmei, Kalari, Krishna R., Ingle, James N., Shepherd, Lois E., Ellis, Matthew J., Goss, Paul E., Barman, Poulami, Carlson, Erin E., Goodnature, Barbara, Goetz, Matthew P., Weinshilboum, Richard M., Gao, Huanyao, Wang, Liewei
Publicado 2021

Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action

por Cairns, Junmei, Ingle, James N., Dudenkov, Tanda M., Kalari, Krishna R., Carlson, Erin E., Na, Jie, Buzdar, Aman U., Robson, Mark E., Ellis, Matthew J., Goss, Paul E., Shepherd, Lois E., Goodnature, Barbara, Goetz, Matthew P., Weinshilboum, Richard M., Li, Hu, Bari, Mehrab Ghanat, Wang, Liewei
Publicado 2020

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome‐Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

por Dudenkov, Tanda M., Liu, Duan, Cairns, Junmei, Devarajan, Sandhya, Zhuang, Yongxian, Ingle, James N., Buzdar, Aman U., Robson, Mark E., Kubo, Michiaki, Batzler, Anthony, Barman, Poulami, Jenkins, Gregory D., Carlson, Erin E., Goetz, Matthew P., Northfelt, Donald W., Moreno‐Aspitia, Alvaro, Desta, Zeruesenay, Reid, Joel M., Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M.
Publicado 2019