Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration

por Lattke, Michael, Reichel, Stephanie N., Magnutzki, Alexander, Abaei, Alireza, Rasche, Volker, Walther, Paul, Calado, Dinis P., Ferger, Boris, Wirth, Thomas, Baumann, Bernd
Publicado 2017

Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases

por Kallemeijn, Wouter W., Lueg, Gregor A., Faronato, Monica, Hadavizadeh, Kate, Goya Grocin, Andrea, Song, Ok-Ryul, Howell, Michael, Calado, Dinis P., Tate, Edward W.
Publicado 2019

A preclinical model of peripheral T‐cell lymphoma GATA3 reveals DNA damage response pathway vulnerability

por Kuczynski, Elizabeth A, Morlino, Giulia, Peter, Alison, Coenen‐Stass, Anna M L, Moss, Jennifer I, Wali, Neha, Delpuech, Oona, Reddy, Avinash, Solanki, Anisha, Sinclair, Charles, Calado, Dinis P, Carnevalli, Larissa S
Publicado 2022

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program

por Frye, Maike, Taddei, Andrea, Dierkes, Cathrin, Martinez-Corral, Ines, Fielden, Matthew, Ortsäter, Henrik, Kazenwadel, Jan, Calado, Dinis P., Ostergaard, Pia, Salminen, Marjo, He, Liqun, Harvey, Natasha L., Kiefer, Friedemann, Mäkinen, Taija
Publicado 2018

RAC1(P29S) Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance

por Lionarons, Daniël A., Hancock, David C., Rana, Sareena, East, Philip, Moore, Christopher, Murillo, Miguel M., Carvalho, Joana, Spencer-Dene, Bradley, Herbert, Eleanor, Stamp, Gordon, Damry, Djamil, Calado, Dinis P., Rosewell, Ian, Fritsch, Ralph, Neubig, Richard R., Molina-Arcas, Miriam, Downward, Julian
Publicado 2019

VE-Cadherin–Mediated Epigenetic Regulation of Endothelial Gene Expression

por Morini, Marco F., Giampietro, Costanza, Corada, Monica, Pisati, Federica, Lavarone, Elisa, Cunha, Sara I., Conze, Lei L., O’Reilly, Nicola, Joshi, Dhira, Kjaer, Svend, George, Roger, Nye, Emma, Ma, Anqi, Jin, Jian, Mitter, Richard, Lupia, Michela, Cavallaro, Ugo, Pasini, Diego, Calado, Dinis P., Dejana, Elisabetta, Taddei, Andrea
Publicado 2018

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

por D’Avola, Annalisa, Legrave, Nathalie, Tajan, Mylène, Chakravarty, Probir, Shearer, Ryan L., King, Hamish W., Kluckova, Katarina, Cheung, Eric C., Clear, Andrew J., Gunawan, Arief S., Zhang, Lingling, James, Louisa K., MacRae, James I., Gribben, John G., Calado, Dinis P., Vousden, Karen H., Riches, John C.
Publicado 2022

Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma

por Apollonio, Benedetta, Spada, Filomena, Petrov, Nedyalko, Cozzetto, Domenico, Papazoglou, Despoina, Jarvis, Peter, Kannambath, Shichina, Terranova-Barberio, Manuela, Amini, Rose-Marie, Enblad, Gunilla, Graham, Charlotte, Benjamin, Reuben, Phillips, Elisabeth, Ellis, Richard, Nuamah, Rosamond, Saqi, Mansoor, Calado, Dinis P., Rosenquist, Richard, Sutton, Lesley A., Salisbury, Jon, Zacharioudakis, Georgios, Vardi, Anna, Hagner, Patrick R., Gandhi, Anita K., Bacac, Marina, Claus, Christina, Umana, Pablo, Jarrett, Ruth F., Klein, Christian, Deutsch, Alexander, Ramsay, Alan G.
Publicado 2023