Crystal Structure of Escherichia coli Polynucleotide Phosphorylase Core Bound to RNase E, RNA and Manganese: Implications for Catalytic Mechanism and RNA Degradosome Assembly

por Nurmohamed, Salima, Vaidialingam, Bhamini, Callaghan, Anastasia J., Luisi, Ben F.
Publicado 2009

Generation of small molecule-binding RNA arrays and their application to fluorogen-binding RNA aptamers

por Henderson, Charlotte A., Rail, Callum A., Butt, Louise E., Vincent, Helen A., Callaghan, Anastasia J.
Publicado 2019

The Crystal Structure of the Escherichia coli RNase E Apoprotein and a Mechanism for RNA Degradation

por Koslover, Daniel J., Callaghan, Anastasia J., Marcaida, Maria J., Garman, Elspeth F., Martick, Monika, Scott, William G., Luisi, Ben F.
Publicado 2008

Recognition of the 70S ribosome and polysome by the RNA degradosome in Escherichia coli

por Tsai, Yi-Chun, Du, Dijun, Domínguez-Malfavón, Lilianha, Dimastrogiovanni, Daniela, Cross, Jonathan, Callaghan, Anastasia J., García-Mena, Jaime, Luisi, Ben F.
Publicado 2012

Characterization of MicA interactions suggests a potential novel means of gene regulation by small non-coding RNAs

por Henderson, Charlotte A., Vincent, Helen A., Stone, Carlanne M., Phillips, Jack O., Cary, Peter D., Gowers, Darren M., Callaghan, Anastasia J.
Publicado 2013

The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado 2015

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado 2015

A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

por Mardle, Charlotte E., Shakespeare, Thomas J., Butt, Louise E., Goddard, Layla R., Gowers, Darren M., Atkins, Helen S., Vincent, Helen A., Callaghan, Anastasia J.
Publicado 2019

Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli

por Nurmohamed, Salima, Vincent, Helen A., Titman, Christopher M., Chandran, Vidya, Pears, Michael R., Du, Dijun, Griffin, Julian L., Callaghan, Anastasia J., Luisi, Ben F.
Publicado 2011

The low-resolution solution structure of Vibrio cholerae Hfq in complex with Qrr1 sRNA

por Vincent, Helen A., Henderson, Charlotte A., Stone, Carlanne M., Cary, Peter D., Gowers, Darren M., Sobott, Frank, Taylor, James E. N., Callaghan, Anastasia J.
Publicado 2012

Identification and analysis of novel small molecule inhibitors of RNase E: Implications for antibacterial targeting and regulation of RNase E

por Mardle, Charlotte E., Goddard, Layla R., Spelman, Bailei C., Atkins, Helen S., Butt, Louise E., Cox, Paul A., Gowers, Darren M., Vincent, Helen A., Callaghan, Anastasia J.
Publicado 2020

Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism

por Stone, Carlanne M., Butt, Louise E., Bufton, Joshua C., Lourenco, Daniel C., Gowers, Darren M., Pickford, Andrew R., Cox, Paul A., Vincent, Helen A., Callaghan, Anastasia J.
Publicado 2017

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions

por Phillips, Jack O, Butt, Louise E, Henderson, Charlotte A, Devonshire, Martin, Healy, Jess, Conway, Stuart J, Locker, Nicolas, Pickford, Andrew R, Vincent, Helen A, Callaghan, Anastasia J
Publicado 2018

Identification of Novel Inhibitors of Escherichia coli DNA Ligase (LigA)

por Alomari, Arqam, Gowland, Robert, Southwood, Callum, Barrow, Jak, Bentley, Zoe, Calvin-Nelson, Jashel, Kaminski, Alice, LeFevre, Matthew, Callaghan, Anastasia J., Vincent, Helen A., Gowers, Darren M.
Publicado 2021

Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region

por Vincent, Helen A., Henderson, Charlotte A., Ragan, Timothy J., Garza-Garcia, Acely, Cary, Peter D., Gowers, Darren M., Malfois, Marc, Driscoll, Paul C., Sobott, Frank, Callaghan, Anastasia J.
Publicado 2012

An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy

por Goddard, Layla R., Mardle, Charlotte E., Gneid, Hassan, Ball, Ciara G., Gowers, Darren M., Atkins, Helen S., Butt, Louise E., Watts, Jonathan K., Vincent, Helen A., Callaghan, Anastasia J.
Publicado 2021

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS

por Henderson, Charlotte A., Vincent, Helen A., Casamento, Alessandra, Stone, Carlanne M., Phillips, Jack O., Cary, Peter D., Sobott, Frank, Gowers, Darren M., Taylor, James E.N., Callaghan, Anastasia J.
Publicado 2013

An Improved Method for Surface Immobilisation of RNA: Application to Small Non-Coding RNA - mRNA Pairing

por Vincent, Helen A., Phillips, Jack O., Henderson, Charlotte A., Roberts, Adam J., Stone, Carlanne M., Mardle, Charlotte E., Butt, Louise E., Gowers, Darren M., Pickford, Andrew R., Callaghan, Anastasia J.
Publicado 2013

Identification of small RNAs associated with RNA chaperone Hfq reveals a new stress response regulator in Actinobacillus pleuropneumoniae

por da Silva, Giarlã Cunha, Rossi, Ciro César, Rosa, Jéssica Nogueira, Sanches, Newton Moreno, Cardoso, Daniela Lopes, Li, Yanwen, Witney, Adam A., Gould, Kate A., Fontes, Patrícia Pereira, Callaghan, Anastasia J., Bossé, Janine Thérèse, Langford, Paul Richard, Bazzolli, Denise Mara Soares
Publicado 2022