In vitro and bioinformatics mechanistic-based approach for cadmium carcinogenicity understanding

por Oldani, Monica, Fabbri, Marco, Melchioretto, Pasquale, Callegaro, Giulia, Fusi, Paola, Gribaldo, Laura, Forcella, Matilde, Urani, Chiara
Publicado 2020

An ensemble learning approach for modeling the systems biology of drug-induced injury

por Aguirre-Plans, Joaquim, Piñero, Janet, Souza, Terezinha, Callegaro, Giulia, Kunnen, Steven J., Sanz, Ferran, Fernandez-Fuentes, Narcis, Furlong, Laura I., Guney, Emre, Oliva, Baldo
Publicado 2021

Identifying multiscale translational safety biomarkers using a network-based systems approach

por Callegaro, Giulia, Schimming, Johannes P., Piñero González, Janet, Kunnen, Steven J., Wijaya, Lukas, Trairatphisan, Panuwat, van den Berk, Linda, Beetsma, Kim, Furlong, Laura I., Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob
Publicado 2023

The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment

por Callegaro, Giulia, Kunnen, Steven J., Trairatphisan, Panuwat, Grosdidier, Solène, Niemeijer, Marije, den Hollander, Wouter, Guney, Emre, Piñero Gonzalez, Janet, Furlong, Laura, Webster, Yue W., Saez-Rodriguez, Julio, Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob
Publicado 2021

Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation

por van der Stel, Wanda, Yang, Huan, Vrijenhoek, Nanette G., Schimming, Johannes P., Callegaro, Giulia, Carta, Giada, Darici, Salihanur, Delp, Johannes, Forsby, Anna, White, Andrew, le Dévédec, Sylvia, Leist, Marcel, Jennings, Paul, Beltman, Joost B., van de Water, Bob, Danen, Erik H. J.
Publicado 2021

Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury

por Copple, Ian M., den Hollander, Wouter, Callegaro, Giulia, Mutter, Fiona E., Maggs, James L., Schofield, Amy L., Rainbow, Lucille, Fang, Yongxiang, Sutherland, Jeffrey J., Ellis, Ewa C., Ingelman-Sundberg, Magnus, Fenwick, Stephen W., Goldring, Christopher E., van de Water, Bob, Stevens, James L., Park, B. Kevin
Publicado 2018

The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

por Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Blomberg, Niklas, Bringezu, Frank, Briggs, Katharine, Callegaro, Giulia, Capella-Gutierrez, Salvador, Centeno, Emilio, Corvi, Javier, Drew, Philip, Drewe, William C., Fernández, José M., Furlong, Laura I., Guney, Emre, Kors, Jan A., Mayer, Miguel Angel, Pastor, Manuel, Piñero, Janet, Ramírez-Anguita, Juan Manuel, Ronzano, Francesco, Rowell, Philip, Saüch-Pitarch, Josep, Valencia, Alfonso, van de Water, Bob, van der Lei, Johan, van Mulligen, Erik, Sanz, Ferran
Publicado 2021