Inhibitors of SARS-CoV-2 PLpro

por Calleja, Dale J., Lessene, Guillaume, Komander, David
Publicado 2022

Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii

por Wilde, Mary-Louise, Ruparel, Ushma, Klemm, Theresa, Lee, V Vern, Calleja, Dale J, Komander, David, Tonkin, Christopher J
Publicado 2023

Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands

por Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J., Nicholson, Sandra E.
Publicado 2023

Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands

por Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J., Nicholson, Sandra E.
Publicado 2021

NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity

por Moecking, Jonas, Laohamonthonkul, Pawat, Chalker, Katelyn, White, Marquitta J., Harapas, Cassandra R., Yu, Chien-Hsiung, Davidson, Sophia, Hrovat-Schaale, Katja, Hu, Donglei, Eng, Celeste, Huntsman, Scott, Calleja, Dale J., Horvat, Jay C., Hansbro, Phil M., O’Donoghue, Robert J.J., Ting, Jenny P., Burchard, Esteban G., Geyer, Matthias, Gerlic, Motti, Masters, Seth L.
Publicado 2021

Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors

por Calleja, Dale J., Kuchel, Nathan, Lu, Bernadine G. C., Birkinshaw, Richard W., Klemm, Theresa, Doerflinger, Marcel, Cooney, James P., Mackiewicz, Liana, Au, Amanda E., Yap, Yu Q., Blackmore, Timothy R, Katneni, Kasiram, Crighton, Elly, Newman, Janet, Jarman, Kate E., Call, Melissa J., Lechtenberg, Bernhard C., Czabotar, Peter E., Pellegrini, Marc, Charman, Susan A., Lowes, Kym N., Mitchell, Jeffrey P., Nachbur, Ueli, Lessene, Guillaume, Komander, David
Publicado 2022

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

por Yu, Chien-Hsiung, Davidson, Sophia, Harapas, Cassandra R., Hilton, James B., Mlodzianoski, Michael J., Laohamonthonkul, Pawat, Louis, Cynthia, Low, Ronnie Ren Jie, Moecking, Jonas, De Nardo, Dominic, Balka, Katherine R., Calleja, Dale J., Moghaddas, Fiona, Ni, Erya, McLean, Catriona A., Samson, Andre L., Tyebji, Shiraz, Tonkin, Christopher J., Bye, Christopher R., Turner, Bradley J., Pepin, Genevieve, Gantier, Michael P., Rogers, Kelly L., McArthur, Kate, Crouch, Peter J., Masters, Seth L.
Publicado 2020

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

por Klemm, Theresa, Ebert, Gregor, Calleja, Dale J, Allison, Cody C, Richardson, Lachlan W, Bernardini, Jonathan P, Lu, Bernadine GC, Kuchel, Nathan W, Grohmann, Christoph, Shibata, Yuri, Gan, Zhong Yan, Cooney, James P, Doerflinger, Marcel, Au, Amanda E, Blackmore, Timothy R, van der Heden van Noort, Gerbrand J, Geurink, Paul P, Ovaa, Huib, Newman, Janet, Riboldi‐Tunnicliffe, Alan, Czabotar, Peter E, Mitchell, Jeffrey P, Feltham, Rebecca, Lechtenberg, Bernhard C, Lowes, Kym N, Dewson, Grant, Pellegrini, Marc, Lessene, Guillaume, Komander, David
Publicado 2020