The P2X(7) Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

por Campagno, Keith E., Mitchell, Claire H.
Publicado 2021

Oral Delivery of the P2Y(12) Receptor Antagonist Ticagrelor Prevents Loss of Photoreceptors in an ABCA4(−/−) Mouse Model of Retinal Degeneration

por Lu, Wennan, Campagno, Keith E., Tso, Huen-Yee, Cenaj, Aurora, Laties, Alan M., Carlsson, Leif G., Mitchell, Claire H.
Publicado 2019

Polarized Cytokine Release Triggered by P2X7 Receptor from Retinal Pigmented Epithelial Cells Dependent on Calcium Influx

por Shao, Xiaolei, Guha, Sonia, Lu, Wennan, Campagno, Keith E., Beckel, Jonathan M., Mills, Jason A., Yang, Wenli, Mitchell, Claire H.
Publicado 2020

Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels

por Beckel, Jonathan M., Gómez, Néstor Más, Lu, Wennan, Campagno, Keith E., Nabet, Bardia, Albalawi, Farraj, Lim, Jason C., Boesze-Battaglia, Kathleen, Mitchell, Claire H.
Publicado 2018

Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressure

por Campagno, Keith E., Lu, Wennan, Jassim, Assraa Hassan, Albalawi, Farraj, Cenaj, Aurora, Tso, Huen-Yee, Clark, Sophia P., Sripinun, Puttipong, Gómez, Néstor Más, Mitchell, Claire H.
Publicado 2021

The P2Y(12) Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4(-/-) Mouse Model of Retinal Degeneration

por Lu, Wennan, Gómez, Néstor M., Lim, Jason C., Guha, Sonia, O’Brien-Jenkins, Ann, Coffey, Erin E., Campagno, Keith E., McCaughey, Stuart A., Laties, Alan M., Carlsson, Leif G., Mitchell, Claire H.
Publicado 2018