AI in drug development: a multidisciplinary perspective

por Gallego, Víctor, Naveiro, Roi, Roca, Carlos, Ríos Insua, David, Campillo, Nuria E.
Publicado 2021

QSAR Modelling to Identify LRRK2 Inhibitors for Parkinson’s Disease

por Sebastián-Pérez, Víctor, Martínez, María Jimena, Gil, Carmen, Campillo, Nuria Eugenia, Martínez, Ana, Ponzoni, Ignacio
Publicado 2019

Finding the Dose for Ceftolozane-Tazobactam in Critically Ill Children with and without Acute Kidney Injury

por Butragueño-Laiseca, Laura, Troconiz, Iñaki F., Grau, Santiago, Campillo, Nuria, García, Xandra, Padilla, Belén, Fernández, Sarah N., Santiago, María José
Publicado 2020

Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of Leishmania GSK-3

por Sebastián-Pérez, Victor, Martínez de Iturrate, Paula, Nácher-Vázquez, Montserrat, Nóvoa, Luis, Pérez, Concepción, Campillo, Nuria E., Gil, Carmen, Rivas, Luis
Publicado 2022

Pharmacokinetics and Pharmacodynamics of Meropenem by Extended or Continuous Infusion in Low Body Weight Critically Ill Patients

por Luque, Sonia, Benítez-Cano, Adela, Larrañaga, Leire, Sorlí, Luisa, Navarrete, María Eugenia, Campillo, Nuria, Carazo, Jesús, Ramos, Isabel, Adalia, Ramón, Grau, Santiago
Publicado 2021

Colistin Use in Patients with Chronic Kidney Disease: Are We Underdosing Patients?

por Sorli, Luisa, Luque, Sonia, Li, Jian, Rodríguez, Eva, Campillo, Nuria, Fernandez, Xenia, Soldado, Jade, Domingo, Ignacio, Montero, Milagro, Grau, Santiago, Horcajada, Juan P.
Publicado 2019

Impact of colistin plasma levels on the clinical outcome of patients with infections caused by extremely drug-resistant Pseudomonas aeruginosa

por Sorlí, Luisa, Luque, Sonia, Segura, Concepción, Campillo, Nuria, Montero, Milagro, Esteve, Erika, Herrera, Sabina, Benito, Natividad, Alvarez-Lerma, Francisco, Grau, Santiago, Horcajada, Juan Pablo
Publicado 2017

Identification of new allosteric sites and modulators of AChE through computational and experimental tools

por Roca, Carlos, Requena, Carlos, Sebastián-Pérez, Víctor, Malhotra, Sony, Radoux, Chris, Pérez, Concepción, Martinez, Ana, Antonio Páez, Juan, Blundell, Tom L., Campillo, Nuria E.
Publicado 2018

Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3

por Sciú, M. Lourdes, Sebastián-Pérez, Victor, Martinez-Gonzalez, Loreto, Benitez, Rocio, Perez, Daniel I., Pérez, Concepción, Campillo, Nuria E., Martinez, Ana, Moyano, E. Laura
Publicado 2018

Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods

por Ginex, Tiziana, Garaigorta, Urtzi, Ramírez, David, Castro, Victoria, Nozal, Vanesa, Maestro, Inés, García-Cárceles, Javier, Campillo, Nuria E., Martinez, Ana, Gastaminza, Pablo, Gil, Carmen
Publicado 2021

Towards discovery of new leishmanicidal scaffolds able to inhibit Leishmania GSK-3

por Martínez de Iturrate, Paula, Sebastián-Pérez, Victor, Nácher-Vázquez, Montserrat, Tremper, Catherine S., Smirlis, Despina, Martín, Julio, Martínez, Ana, Campillo, Nuria E., Rivas, Luis, Gil, Carmen
Publicado 2019

Osteoarticular Cryptococcosis Successfully Treated with High-Dose Liposomal Amphotericin B Followed by Oral Fluconazole

por Deus, Guillem, Gómez-Zorrilla, Silvia, Echeverria-Esnal, Daniel, Siverio, Ana, Güerri-Fernandez, Robert, Ares, Jesús, Campillo, Nuria, Letang, Emili, Knobel, Hernando, Grau, Santiago, Horcajada, Juan Pablo
Publicado 2021

Multitarget drugs as potential therapeutic agents for alzheimer’s disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors

por González-Naranjo, Pedro, Pérez, Concepción, González-Sánchez, Marina, Gironda-Martínez, Adrián, Ulzurrun, Eugenia, Bartolomé, Fernando, Rubio-Fernández, Marcos, Martin-Requero, Angeles, Campillo, Nuria E., Páez, Juan A.
Publicado 2022

Virtual Screening of FDA-Approved Drugs against Triose Phosphate Isomerase from Entamoeba histolytica and Giardia lamblia Identifies Inhibitors of Their Trophozoite Growth Phase

por Juárez-Saldivar, Alfredo, Barbosa-Cabrera, Elizabeth, Lara-Ramírez, Edgar E., Paz-González, Alma D., Martínez-Vázquez, Ana V., Bocanegra-García, Virgilio, Palos, Isidro, Campillo, Nuria E., Rivera, Gildardo
Publicado 2021

Hybridizing Feature Selection and Feature Learning Approaches in QSAR Modeling for Drug Discovery

por Ponzoni, Ignacio, Sebastián-Pérez, Víctor, Requena-Triguero, Carlos, Roca, Carlos, Martínez, María J., Cravero, Fiorella, Díaz, Mónica F., Páez, Juan A., Arrayás, Ramón Gómez, Adrio, Javier, Campillo, Nuria E.
Publicado 2017

QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease

por Ponzoni, Ignacio, Sebastián-Pérez, Víctor, Martínez, María J., Roca, Carlos, De la Cruz Pérez, Carlos, Cravero, Fiorella, Vazquez, Gustavo E., Páez, Juan A., Díaz, Mónica F., Campillo, Nuria E.
Publicado 2019

Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target

por García-Dorival, Isabel, Cuesta-Geijo, Miguel Ángel, Barrado-Gil, Lucía, Galindo, Inmaculada, Garaigorta, Urtzi, Urquiza, Jesús, Puerto, Ana del, Campillo, Nuria E., Martínez, Ana, Gastaminza, Pablo, Gil, Carmen, Alonso, Covadonga
Publicado 2021

Suboptimal Concentrations of Ceftazidime/Avibactam (CAZ-AVI) May Select for CAZ-AVI Resistance in Extensively Drug-Resistant Pseudomonas aeruginosa: In Vivo and In Vitro Evidence

por Lopez-Montesinos, Inmaculada, Montero, María Milagro, Domene-Ochoa, Sandra, López-Causapé, Carla, Echeverria, Daniel, Sorlí, Luisa, Campillo, Nuria, Luque, Sonia, Padilla, Eduardo, Prim, Nuria, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P.
Publicado 2022

Time-Kill Evaluation of Antibiotic Combinations Containing Ceftazidime-Avibactam against Extensively Drug-Resistant Pseudomonas aeruginosa and Their Potential Role against Ceftazid...

por Montero, María M., Domene Ochoa, Sandra, López-Causapé, Carla, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, López Montesinos, Inmaculada, Padilla, Eduardo, Prim, Núria, Angulo-Brunet, Ariadna, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P.
Publicado 2021

Impact of ceftolozane/tazobactam concentrations in continuous infusion against extensively drug-resistant Pseudomonas aeruginosa isolates in a hollow-fiber infection model

por Montero, María M., Domene-Ochoa, Sandra, López-Causapé, Carla, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, Padilla, Eduardo, Prim, Núria, Ferrer-Alapont, Lorena, Angulo-Brunet, Ariadna, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P.
Publicado 2021