FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis

por Monsalve, Anuntxi, Canals, Isaac, Oburoglu, Leal
Publicado 2022

Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches

por Benetó, Noelia, Vilageliu, Lluïsa, Grinberg, Daniel, Canals, Isaac
Publicado 2020

EXTL2 and EXTL3 inhibition with siRNAs as a promising substrate reduction therapy for Sanfilippo C syndrome

por Canals, Isaac, Benetó, Noelia, Cozar, Mónica, Vilageliu, Lluïsa, Grinberg, Daniel
Publicado 2015

Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence

por Oburoglu, Leal, Mansell, Els, Canals, Isaac, Sigurdsson, Valgardur, Guibentif, Carolina, Soneji, Shamit, Woods, Niels‐Bjarne
Publicado 2021

Transcription Factor–Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo

por Trovato, Francesco, Stefani, Francesca Romana, Li, Jiaxin, Zetterdahl, Oskar G., Canals, Isaac, Ahlenius, Henrik, Bengzon, Johan
Publicado 2023

NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities

por Tolomeo, Anna Maria, Laterza, Cecilia, Grespan, Eleonora, Michielin, Federica, Canals, Isaac, Kokaia, Zaal, Muraca, Maurizio, Gagliano, Onelia, Elvassore, Nicola
Publicado 2021

Transcription factor-based direct conversion of human fibroblasts to functional astrocytes

por Quist, Ella, Trovato, Francesco, Avaliani, Natalia, Zetterdahl, Oskar G., Gonzalez-Ramos, Ana, Hansen, Marita G., Kokaia, Merab, Canals, Isaac, Ahlenius, Henrik
Publicado 2022

Therapeutic strategies based on modified U1 snRNAs and chaperones for Sanfilippo C splicing mutations

por Matos, Liliana, Canals, Isaac, Dridi, Larbi, Choi, Yoo, Prata, Maria João, Jordan, Peter, Desviat, Lourdes R, Pérez, Belén, Pshezhetsky, Alexey V, Grinberg, Daniel, Alves, Sandra, Vilageliu, Lluïsa
Publicado 2014

Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks

por Canals, Isaac, Soriano, Jordi, Orlandi, Javier G., Torrent, Roger, Richaud-Patin, Yvonne, Jiménez-Delgado, Senda, Merlin, Simone, Follenzi, Antonia, Consiglio, Antonella, Vilageliu, Lluïsa, Grinberg, Daniel, Raya, Angel
Publicado 2015

Neuronal and Astrocytic Differentiation from Sanfilippo C Syndrome iPSCs for Disease Modeling and Drug Development

por Benetó, Noelia, Cozar, Monica, Castilla-Vallmanya, Laura, Zetterdahl, Oskar G., Sacultanu, Madalina, Segur-Bailach, Eulalia, García-Morant, María, Ribes, Antonia, Ahlenius, Henrik, Grinberg, Daniel, Vilageliu, Lluïsa, Canals, Isaac
Publicado 2020

Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons

por Galera-Monge, Teresa, Zurita-Díaz, Francisco, Canals, Isaac, Grønning Hansen, Marita, Rufián-Vázquez, Laura, Ehinger, Johannes K., Elmér, Eskil, Martin, Miguel A., Garesse, Rafael, Ahlenius, Henrik, Gallardo, M. Esther
Publicado 2020

Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia

por Canals, Isaac, Comella-Bolla, Andrea, Cepeda-Prado, Efrain, Avaliani, Natalia, Crowe, James A, Oburoglu, Leal, Bruzelius, Andreas, King, Naomi, Pajares, María A, Pérez-Sala, Dolores, Heuer, Andreas, Rylander Ottosson, Daniella, Soriano, Jordi, Ahlenius, Henrik
Publicado 2023