The Kinetic Component in Drug Discovery: Using the Most Basic Pharmacological Concepts to Advance in Selecting Drugs to Combat CNS Diseases

por Franco, Rafael, Castelló, Josema, Canela, Enric I.
Publicado 2020

Functional Fine-Tuning of Metabolic Pathways by the Endocannabinoid System—Implications for Health and Disease

por Moreno, Estefanía, Cavic, Milena, Canela, Enric I.
Publicado 2021

The Interplay between Cancer Biology and the Endocannabinoid System—Significance for Cancer Risk, Prognosis and Response to Treatment

por Moreno, Estefanía, Cavic, Milena, Krivokuca, Ana, Canela, Enric I.
Publicado 2020

Nk3R blockade has sex-divergent effects on memory in mice

por Florido, Antonio, Moreno, Estefanía, Canela, Enric I., Andero, Raül
Publicado 2022

Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression

por Aguinaga, David, Medrano, Mireia, Vega-Quiroga, Ignacio, Gysling, Katia, Canela, Enric I., Navarro, Gemma, Franco, Rafael
Publicado 2018

Molecular Evidence of Adenosine Deaminase Linking Adenosine A(2A) Receptor and CD26 Proteins

por Moreno, Estefanía, Canet, Júlia, Gracia, Eduard, Lluís, Carme, Mallol, Josefa, Canela, Enric I., Cortés, Antoni, Casadó, Vicent
Publicado 2018

Significant Functional Differences Between Dopamine D(4) Receptor Polymorphic Variants Upon Heteromerization with α(1A) Adrenoreceptors

por Homar-Ruano, Patricia, Cai, Ning-Sheng, Casadó-Anguera, Verònica, Casadó, Vicent, Ferré, Sergi, Moreno, Estefanía, Canela, Enric I.
Publicado 2023

Basic Concepts in G-Protein-Coupled Receptor Homo- and Heterodimerization

por Franco, Rafael, Casadó, Vicent, Cortés, Antoni, Ferrada, Carla, Mallol, Josefa, Woods, Amina, Lluis, Carme, Canela, Enric I., Ferré, Sergi
Publicado 2007

Adenosine A(2A) Receptors and A(2A) Receptor Heteromers as Key Players in Striatal Function

por Ferré, Sergi, Quiroz, César, Orru, Marco, Guitart, Xavier, Navarro, Gemma, Cortés, Antonio, Casadó, Vicent, Canela, Enric I., Lluis, Carme, Franco, Rafael
Publicado 2011

Detection of Heteromers Formed by Cannabinoid CB(1), Dopamine D(2), and Adenosine A(2A) G-Protein-Coupled Receptors by Combining Bimolecular Fluorescence Complementation and Biolum...

por Navarro, Gemma, Carriba, Paulina, Gandí, Jorge, Ciruela, Francisco, Casadó, Vicent, Cortés, Antoni, Mallol, Josefa, Canela, Enric I., Lluis, Carmen, Franco, Rafael
Publicado 2008

Striatal Pre- and Postsynaptic Profile of Adenosine A(2A) Receptor Antagonists

por Orru, Marco, Bakešová, Jana, Brugarolas, Marc, Quiroz, César, Beaumont, Vahri, Goldberg, Steven R., Lluís, Carme, Cortés, Antoni, Franco, Rafael, Casadó, Vicent, Canela, Enric I., Ferré, Sergi
Publicado 2011

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase

por Navarro, Gemma, Cordomí, Arnau, Casadó-Anguera, Verónica, Moreno, Estefanía, Cai, Ning-Sheng, Cortés, Antoni, Canela, Enric I., Dessauer, Carmen W., Casadó, Vicent, Pardo, Leonardo, Lluís, Carme, Ferré, Sergi
Publicado 2018

N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, a...

por Franco, Rafael, Aguinaga, David, Reyes, Irene, Canela, Enric I., Lillo, Jaume, Tarutani, Airi, Hasegawa, Masato, del Ser-Badia, Anna, del Rio, José A., Kreutz, Michael R., Saura, Carlos A., Navarro, Gemma
Publicado 2018

Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB(2) Receptors

por Martínez-Pinilla, Eva, Varani, Katia, Reyes-Resina, Irene, Angelats, Edgar, Vincenzi, Fabrizio, Ferreiro-Vera, Carlos, Oyarzabal, Julen, Canela, Enric I., Lanciego, José L., Nadal, Xavier, Navarro, Gemma, Borea, Pier Andrea, Franco, Rafael
Publicado 2017

Cross-communication between G(i) and G(s) in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain

por Navarro, Gemma, Cordomí, Arnau, Brugarolas, Marc, Moreno, Estefanía, Aguinaga, David, Pérez-Benito, Laura, Ferre, Sergi, Cortés, Antoni, Casadó, Vicent, Mallol, Josefa, Canela, Enric I., Lluís, Carme, Pardo, Leonardo, McCormick, Peter J., Franco, Rafael
Publicado 2018

Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes

por Navarro, Gemma, Varani, Katia, Reyes-Resina, Irene, Sánchez de Medina, Verónica, Rivas-Santisteban, Rafael, Sánchez-Carnerero Callado, Carolina, Vincenzi, Fabrizio, Casano, Salvatore, Ferreiro-Vera, Carlos, Canela, Enric I., Borea, Pier Andrea, Nadal, Xavier, Franco, Rafael
Publicado 2018

Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB(1) and Serotonin 5-HT(2A) Receptors

por Viñals, Xavier, Moreno, Estefanía, Lanfumey, Laurence, Cordomí, Arnau, Pastor, Antoni, de La Torre, Rafael, Gasperini, Paola, Navarro, Gemma, Howell, Lesley A., Pardo, Leonardo, Lluís, Carmen, Canela, Enric I., McCormick, Peter J., Maldonado, Rafael, Robledo, Patricia
Publicado 2015

Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with G(i) and G(s)

por Navarro, Gemma, Cordomí, Arnau, Zelman-Femiak, Monika, Brugarolas, Marc, Moreno, Estefania, Aguinaga, David, Perez-Benito, Laura, Cortés, Antoni, Casadó, Vicent, Mallol, Josefa, Canela, Enric I., Lluís, Carme, Pardo, Leonardo, García-Sáez, Ana J., McCormick, Peter J., Franco, Rafael
Publicado 2016

Modulation of dopamine D(1) receptors via histamine H(3) receptors is a novel therapeutic target for Huntington's disease

por Moreno-Delgado, David, Puigdellívol, Mar, Moreno, Estefanía, Rodríguez-Ruiz, Mar, Botta, Joaquín, Gasperini, Paola, Chiarlone, Anna, Howell, Lesley A, Scarselli, Marco, Casadó, Vicent, Cortés, Antoni, Ferré, Sergi, Guzmán, Manuel, Lluís, Carmen, Alberch, Jordi, Canela, Enric I, Ginés, Silvia, McCormick, Peter J
Publicado 2020

Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43

por Maroto, Irene B., Costas-Insua, Carlos, Berthoux, Coralie, Moreno, Estefanía, Ruiz-Calvo, Andrea, Montero-Fernández, Carlos, Macías-Camero, Andrea, Martín, Ricardo, García-Font, Nuria, Sánchez-Prieto, José, Marsicano, Giovanni, Bellocchio, Luigi, Canela, Enric I., Casadó, Vicent, Galve-Roperh, Ismael, Núñez, Ángel, Fernández de Sevilla, David, Rodríguez-Crespo, Ignacio, Castillo, Pablo E., Guzmán, Manuel
Publicado 2023