IL-1 receptor antagonist, MIS-C, and the peculiar autoimmunity of SARS-CoV-2

por Bassiri, Hamid, Canna, Scott W
Publicado 2022

Should COVID-19 take advice from rheumatologists?

por Kernan, Kate F, Canna, Scott W
Publicado 2020

Highways to hell: Mechanism-based management of cytokine storm syndromes

por Canna, Scott W., Cron, Randy Q.
Publicado 2020

A 17 year old with isolated proximal tibiofibular joint arthritis

por Canna, Scott W, Chauvin, Nancy A, Burnham, Jon M
Publicado 2013

Chronic, Systemic Interleukin-18 Does Not Promote Macular Degeneration or Choroidal Neovascularization

por Canna, Scott W., Shi, Guangpu, Gery, Igal, Sen, H. Nida
Publicado 2017

Complementary HLH susceptibility factors converge on CD8 T-cell hyperactivation

por Landy, Emily, Varghese, Jemy, Dang, Vinh, Szymczak-Workman, Andrea, Kane, Lawrence P., Canna, Scott W.
Publicado 2023

Deep neural networks with knockoff features identify nonlinear causal relations and estimate effect sizes in complex biological systems

por Fan, Zhenjiang, Kernan, Kate F, Sriram, Aditya, Benos, Panayiotis V, Canna, Scott W, Carcillo, Joseph A, Kim, Soyeon, Park, Hyun Jung
Publicado 2023

Sepsis with liver dysfunction and coagulopathy predicts an inflammatory pattern of macrophage activation

por Anderko, Renee R., Gómez, Hernando, Canna, Scott W., Shakoory, Bita, Angus, Derek C., Yealy, Donald M., Huang, David T., Kellum, John A., Carcillo, Joseph A.
Publicado 2022

Genetic and commensal induction of IL-18 drive intestinal epithelial MHCII via IFNγ

por Van Der Kraak, L. A., Schneider, C., Dang, V., Burr, A.H.P., Weiss, E.S., Varghese, J,A., Yang, L., Hand, T.W., Canna, S.W.
Publicado 2021

Proceedings from the 2(nd) Next Gen Therapies for Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome symposium held on October 3-4, 2019

por Canna, Scott W., Schulert, Grant S., de Jesus, Adriana, Pickering, Alex, Brunner, Hermine, Gadina, Massimo, Levine, Stewart, Goldbach-Mansky, Raphaela, Boutelle, Jonathan, Sinha, Rashmi, DeBenedetti, Fabrizio, Grom, Alexei
Publicado 2020

Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products

por Cruz, Patricia Castillo-dela, Wanek, Alanna G., Kumar, Pawan, An, Xiaojing, Elsegeiny, Waleed, Horne, William, Fitch, Adam, Burr, Ansen H.P., Gopalakrishna, Kathyayini P., Chen, Kong, Methé, Barbara A., Canna, Scott W., Hand, Timothy W., Kolls, Jay K.
Publicado 2019

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface

por Moghaddas, Fiona, Zeng, Ping, Zhang, Yuxia, Schützle, Heike, Brenner, Sebastian, Hofmann, Sigrun R., Berner, Reinhard, Zhao, Yuanbo, Lu, Bingtai, Chen, Xiaoyun, Zhang, Li, Cheng, Suyun, Winkler, Stefan, Lehmberg, Kai, Canna, Scott W., Czabotar, Peter E., Wicks, Ian P., De Nardo, Dominic, Hedrich, Christian M., Zeng, Huasong, Masters, Seth L.
Publicado 2018

Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction

por Diorio, Caroline, Shraim, Rawan, Vella, Laura A., Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Canna, Scott W., Henrickson, Sarah E., McNerney, Kevin O., Balamuth, Frances, Burudpakdee, Chakkapong, Lee, Jessica, Leng, Tomas, Farrel, Alvin, Lambert, Michele P., Sullivan, Kathleen E., Wherry, E. John, Teachey, David T., Bassiri, Hamid, Behrens, Edward M.
Publicado 2021

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

por Canna, Scott W., de Jesus, Adriana Almeida, Gouni, Sushanth, Brooks, Stephen R., Marrero, Bernadette, Liu, Yin, DiMattia, Michael A., Zaal, Kristien J.M., Montealegre Sanchez, Gina A., Kim, Hanna, Chapelle, Dawn, Plass, Nicole, Huang, Yan, Villarino, Alejandro V., Biancotto, Angelique, Fleisher, Thomas A., Duncan, Joseph A., O’Shea, John J, Benseler, Susanne, Grom, Alexei, Deng, Zuoming, Laxer, Ronald M, Goldbach-Mansky, Raphaela
Publicado 2014

Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials

por Qin, Yidi, Kernan, Kate F., Fan, Zhenjiang, Park, Hyun-Jung, Kim, Soyeon, Canna, Scott W., Kellum, John A., Berg, Robert A., Wessel, David, Pollack, Murray M., Meert, Kathleen, Hall, Mark, Newth, Christopher, Lin, John C., Doctor, Allan, Shanley, Tom, Cornell, Tim, Harrison, Rick E., Zuppa, Athena F., Banks, Russell, Reeder, Ron W., Holubkov, Richard, Notterman, Daniel A., Michael Dean, J., Carcillo, Joseph A.
Publicado 2022

Type I interferon signature and cycling lymphocytes in macrophage activation syndrome

por Huang, Zhengping, Brodeur, Kailey E., Chen, Liang, Du, Wobma, Holly, Hsu, Evan E., Liu, Meng, Chang, Joyce C., Chang, Margaret H., Chou, Janet, Day-Lewis, Megan, Dedeoglu, Fatma, Halyabar, Olha, Lederer, James A., Li, Tianwang, Lo, Mindy S., Lu, Meiping, Meidan, Esra, Newburger, Jane W., Randolph, Adrienne G., Son, Mary Beth, Sundel, Robert P., Taylor, Maria L., Wu, Huaxiang, Zhou, Qing, Canna, Scott W., Wei, Kevin, Henderson, Lauren A., Nigrovic, Peter A., Lee, Pui Y.
Publicado 2023

mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome

por Huang, Zhengping, You, Xiaomeng, Chen, Liang, Du, Yan, Brodeur, Kailey, Jee, Hyuk, Wang, Qiang, Linder, Grace, Darbousset, Roxane, Cunin, Pierre, Chang, Margaret H., Wactor, Alexandra, Wauford, Brian M., Todd, Marc J. C., Wei, Kevin, Li, Ying, Levescot, Anais, Iwakura, Yoichiro, Pascual, Virginia, Baldwin, Nicole E., Quartier, Pierre, Li, Tianwang, Gianatasio, Maria T., Hasserjian, Robert P., Henderson, Lauren A., Sykes, David B., Mellins, Elizabeth D., Canna, Scott W., Charles, Julia F., Nigrovic, Peter A., Lee, Pui Y.
Publicado 2022

An immune-based biomarker signature is associated with mortality in COVID-19 patients

por Abers, Michael S., Delmonte, Ottavia M., Ricotta, Emily E., Fintzi, Jonathan, Fink, Danielle L., de Jesus, Adriana A. Almeida, Zarember, Kol A., Alehashemi, Sara, Oikonomou, Vasileios, Desai, Jigar V., Canna, Scott W., Shakoory, Bita, Dobbs, Kerry, Imberti, Luisa, Sottini, Alessandra, Quiros-Roldan, Eugenia, Castelli, Francesco, Rossi, Camillo, Brugnoni, Duilio, Biondi, Andrea, Bettini, Laura Rachele, D’Angio’, Mariella, Bonfanti, Paolo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Gliniewicz, Emily F., Shaw, Elana, Kahle, Dana E., Rastegar, Andre T., Stack, Michael, Myint-Hpu, Katherine, Levinson, Susan L., DiNubile, Mark J., Chertow, Daniel W., Burbelo, Peter D., Cohen, Jeffrey I., Calvo, Katherine R., Tsang, John S., Su, Helen C., Gallin, John I., Kuhns, Douglas B., Goldbach-Mansky, Raphaela, Lionakis, Michail S., Notarangelo, Luigi D.
Publicado 2021