TPX2 joins 53BP1 to maintain DNA repair and fork stability

por Cantor, Sharon
Publicado 2019

Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia

por Brosh, Robert M., Cantor, Sharon B.
Publicado 2014

Fork Protection and Therapy Resistance in Hereditary Breast Cancer

por Cantor, Sharon B., Calvo, Jennifer A.
Publicado 2018

Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer

por Wang, Yue, Ung, Matthew H., Cantor, Sharon, Cheng, Chao
Publicado 2017

Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses

por Peng, Min, Xie, Jenny, Ucher, Anna, Stavnezer, Janet, Cantor, Sharon B
Publicado 2014

Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand

por Gupta, Rigu, Sharma, Sudha, Doherty, Kevin M., Sommers, Joshua A., Cantor, Sharon B., Brosh, Robert M.
Publicado 2006

Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4

por Guillemette, Shawna, Serra, Ryan W., Peng, Min, Hayes, Janelle A., Konstantinopoulos, Panagiotis A., Green, Michael R., Cantor, Sharon B.
Publicado 2015

FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response

por Xie, Jenny, Peng, Min, Guillemette, Shawna, Quan, Steven, Maniatis, Stephanie, Wu, Yuliang, Venkatesh, Aditya, Shaffer, Scott A., Brosh, Robert M., Cantor, Sharon B.
Publicado 2012

Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability

por Nayak, Sumeet, Calvo, Jennifer A., Cong, Ke, Peng, Min, Berthiaume, Emily, Jackson, Jessica, Zaino, Angela M., Vindigni, Alessandro, Hadden, M. Kyle, Cantor, Sharon B.
Publicado 2020

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress

por Peng, Min, Cong, Ke, Panzarino, Nicholas J., Nayak, Sumeet, Calvo, Jennifer, Deng, Bin, Zhu, Lihua Julie, Morocz, Monika, Hegedus, Lili, Haracska, Lajos, Cantor, Sharon B.
Publicado 2018

Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling

por Lee, Wei Ting C., Yin, Yandong, Morten, Michael J., Tonzi, Peter, Gwo, Pam Pam, Odermatt, Diana C., Modesti, Mauro, Cantor, Sharon B., Gari, Kerstin, Huang, Tony T., Rothenberg, Eli
Publicado 2021

Replication Fork Stability Confers Chemoresistance in BRCA-deficient Cells

por Chaudhuri, Arnab Ray, Callen, Elsa, Ding, Xia, Gogola, Ewa, Duarte, Alexandra A., Lee, Ji-Eun, Wong, Nancy, Lafarga, Vanessa, Calvo, Jennifer A., Panzarino, Nicholas J., John, Sam, Day, Amanda, Crespo, Anna Vidal, Shen, Binghui, Starnes, Linda M., de Ruiter, Julian R., Daniel, Jeremy A., Konstantinopoulos, Panagiotis A., Cortez, David, Cantor, Sharon B., Fernandez-Capetillo, Oscar, Ge, Kai, Jonkers, Jos, Rottenberg, Sven, Sharan, Shyam K., Nussenzweig, André
Publicado 2016