Use of a Molecular Switch Probe to Activate or Inhibit GIRK1 Heteromers In Silico Reveals a Novel Gating Mechanism

por Gazgalis, Dimitrios, Cantwell, Lucas, Xu, Yu, Thakur, Ganesh A., Cui, Meng, Guarnieri, Frank, Logothetis, Diomedes E.
Publicado 2022

Dose-dependent effects of GAT107, a novel allosteric agonist-positive allosteric modulator (ago-PAM) for the α7 nicotinic cholinergic receptor: a BOLD phMRI and connectivity study...

por Brems, Brittany M., Sullivan, Erin E., Connolly, Jenna G., Zhang, Jingchun, Chang, Arnold, Ortiz, Richard, Cantwell, Lucas, Kulkarni, Praveen, Thakur, Ganesh A., Ferris, Craig F.
Publicado 2023

A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels

por Cui, Meng, Alhamshari, Yaser, Cantwell, Lucas, EI-Haou, Said, Eptaminitaki, Giasemi C., Chang, Mengmeng, Abou-Assali, Obada, Tan, Haozhou, Xu, Keman, Masotti, Meghan, Plant, Leigh D., Thakur, Ganesh A., Noujaim, Sami F., Milnes, James, Logothetis, Diomedes E.
Publicado 2021