Cytosolic calcium ions exert a major influence on the firing rate and maintenance of pacemaker activity in guinea-pig sinus node

por Capel, Rebecca A., Terrar, Derek A.
Publicado 2015

The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat

por Capel, Rebecca A., Terrar, Derek A.
Publicado 2015

Cardiac deficiency of P21-activated kinase 1 promotes atrial arrhythmogenesis in mice following adrenergic challenge

por Jung, Eunjeong, Capel, Rebecca, Jiang, Congshan, Venturi, Elisa, Neagu, Georgiana, Pearcey, Sarah, Zhou, Yafei, Zhang, Yanmin, Lei, Ming
Publicado 2023

Correction to: ‘Cardiac deficiency of P21-activated kinase 1 promotes atrial arrhythmogenesis in mice following adrenergic challenge’

por Jung, Eunjeong, Capel, Rebecca, Jiang, Congshan, Venturi, Elisa, Neagu, Georgiana, Pearcey, Sarah, Zhou, Yafei, Zhang, Yanmin, Lei, Ming
Publicado 2023

Mapping cardiac microstructure of rabbit heart in different mechanical states by high resolution diffusion tensor imaging: A proof-of-principle study

por Teh, Irvin, Burton, Rebecca A.B., McClymont, Darryl, Capel, Rebecca A., Aston, Daniel, Kohl, Peter, Schneider, Jürgen E.
Publicado 2016

IP(3)-mediated Ca(2+) release regulates atrial Ca(2+) transients and pacemaker function by stimulation of adenylyl cyclases

por Capel, Rebecca A., Bose, Samuel J., Collins, Thomas P., Rajasundaram, Skanda, Ayagama, Thamali, Zaccolo, Manuela, Burton, Rebecca-Ann Beatrice, Terrar, Derek A.
Publicado 2021

Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine

por Whittaker, Dominic G., Capel, Rebecca A., Hendrix, Maurice, Chan, Xin Hui S., Herring, Neil, White, Nicholas J., Mirams, Gary R., Burton, Rebecca-Ann B.
Publicado 2021

Inhibition of adenylyl cyclase 1 by ST034307 inhibits IP(3)-evoked changes in sino-atrial node beat rate

por Bose, Samuel J., Read, Matthew J., Akerman, Emily, Capel, Rebecca A., Ayagama, Thamali, Russell, Angela, Terrar, Derek A., Zaccolo, Manuela, Burton, Rebecca A. B.
Publicado 2022

A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue

por Ayagama, Thamali, Bose, Samuel J., Capel, Rebecca A., Priestman, David A., Berridge, Georgina, Fischer, Roman, Galione, Antony, Platt, Frances M., Kramer, Holger, Burton, Rebecca A.B.
Publicado 2021

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current I(f): Novel electrophysiological insights and therapeutic potential

por Capel, Rebecca A., Herring, Neil, Kalla, Manish, Yavari, Arash, Mirams, Gary R., Douglas, Gillian, Bub, Gil, Channon, Keith, Paterson, David J., Terrar, Derek A., Burton, Rebecca-Ann B.
Publicado 2015

Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca(2+) transients in murine heart

por Wen, Q., Gandhi, K., Capel, Rebecca A., Hao, G., O'Shea, C., Neagu, G., Pearcey, S., Pavlovic, D., Terrar, Derek A., Wu, J., Faggian, G., Camelliti, Patrizia, Lei, M.
Publicado 2018

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart

por Aston, Daniel, Capel, Rebecca A., Ford, Kerrie L., Christian, Helen C., Mirams, Gary R., Rog-Zielinska, Eva A., Kohl, Peter, Galione, Antony, Burton, Rebecca A. B., Terrar, Derek A.
Publicado 2017

Load-dependent effects of apelin on murine cardiomyocytes

por Peyronnet, Rémi, Bollensdorff, Christian, Capel, Rebecca A., Rog-Zielinska, Eva A., Woods, Christopher E., Charo, David N., Lookin, Oleg, Fajardo, Giovanni, Ho, Michael, Quertermous, Thomas, Ashley, Euan A., Kohl, Peter
Publicado 2017

Cardiovascular Concentration-Effect Relationships of Amodiaquine and its Metabolite Desethylamodiaquine: Clinical and Pre-clinical Studies

por Chan, Xin Hui S, Chotsiri, Palang, Capel, Rebecca A, Pike, James, Hanboonkunupakarn, Borimas, Lee, Sue J, Hanafiah, Maryam, Win, Yan Naung, Cremer, Maegan, Kiechel, Jean-René, Ogutu, Bernhards, Taylor, Walter RJ, Burton, Rebecca-Ann B, Tarning, Joel, White, Nicholas J
Publicado 2023

Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Sig...

por Capel, Rebecca A., Bolton, Emma L., Lin, Wee K., Aston, Daniel, Wang, Yanwen, Liu, Wei, Wang, Xin, Burton, Rebecca-Ann B., Bloor-Young, Duncan, Shade, Kai-Ting, Ruas, Margarida, Parrington, John, Churchill, Grant C., Lei, Ming, Galione, Antony, Terrar, Derek A.
Publicado 2015

Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics

por Burton, Rebecca-Ann B., Tomek, Jakub, Ambrosi, Christina M., Larsen, Hege E., Sharkey, Amy R., Capel, Rebecca A., Corbett, Alexander D., Bilton, Samuel, Klimas, Aleksandra, Stephens, Guy, Cremer, Maegan, Bose, Samuel J., Li, Dan, Gallone, Giuseppe, Herring, Neil, Mann, Edward O., Kumar, Abhinav, Kramer, Holger, Entcheva, Emilia, Paterson, David J., Bub, Gil
Publicado 2020