Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent

por Sabbieti, Maria Giovanna, Agas, Dimitrios, Capitani, Melania, Marchetti, Luigi, Concetti, Antonio, Vullo, Cecilia, Catone, Giuseppe, Gabai, Vladimir, Shifrin, Victor, Sherman, Michael Y, Shneider, Alexander, Venanzi, Franco M
Publicado 2015

Pathogenic Interleukin-10 Receptor Alpha Variants in Humans — Balancing Natural Selection and Clinical Implications

por Aschenbrenner, Dominik, Ye, Ziqing, Zhou, Ying, Hu, Wenhui, Brooks, Isabel, Williams, Isabelle, Capitani, Melania, Gartner, Lisa, Kotlarz, Daniel, Snapper, Scott B., Klein, Christoph, Muise, Aleixo M., Marsden, Brian D., Huang, Ying, Uhlig, Holm H.
Publicado 2022

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

por Schulthess, Julie, Pandey, Sumeet, Capitani, Melania, Rue-Albrecht, Kevin C., Arnold, Isabelle, Franchini, Fanny, Chomka, Agnieszka, Ilott, Nicholas E., Johnston, Daniel G.W., Pires, Elisabete, McCullagh, James, Sansom, Stephen N., Arancibia-Cárcamo, Carolina V., Uhlig, Holm H., Powrie, Fiona
Publicado 2019

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2

por Mukhopadhyay, Subhankar, Heinz, Eva, Porreca, Immacolata, Alasoo, Kaur, Yeung, Amy, Yang, Huei-Ting, Schwerd, Tobias, Forbester, Jessica L., Hale, Christine, Agu, Chukwuma A., Choi, Yoon Ha, Rodrigues, Julia, Capitani, Melania, Jostins-Dean, Luke, Thomas, David C., Travis, Simon, Gaffney, Daniel, Skarnes, William C., Thomson, Nicholas, Uhlig, Holm H., Dougan, Gordon, Powrie, Fiona
Publicado 2019

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism

por Cavounidis, Athena, Pandey, Sumeet, Capitani, Melania, Friedrich, Matthias, Cross, Amy, Gartner, Lisa, Aschenbrenner, Dominik, Kim-Schulze, Seunghee, Lam, Ying Ka, Berridge, Georgina, McGovern, Dermot P. B., Kessler, Benedikt, Fischer, Roman, Klenerman, Paul, Hester, Joanna, Issa, Fadi, Torres, Esther A., Powrie, Fiona, Gochuico, Bernadette R., Gahl, William A., Cohen, Louis, Uhlig, Holm H.
Publicado 2022

A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis

por Schwerd, Tobias, Twigg, Stephen R.F., Aschenbrenner, Dominik, Manrique, Santiago, Miller, Kerry A., Taylor, Indira B., Capitani, Melania, McGowan, Simon J., Sweeney, Elizabeth, Weber, Astrid, Chen, Liye, Bowness, Paul, Riordan, Andrew, Cant, Andrew, Freeman, Alexandra F., Milner, Joshua D., Holland, Steven M., Frede, Natalie, Müller, Miryam, Schmidt-Arras, Dirk, Grimbacher, Bodo, Wall, Steven A., Jones, E. Yvonne, Wilkie, Andrew O.M., Uhlig, Holm H.
Publicado 2017

Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

por Wang, Lin, Aschenbrenner, Dominik, Zeng, Zhiyang, Cao, Xiya, Mayr, Daniel, Mehta, Meera, Capitani, Melania, Warner, Neil, Pan, Jie, Wang, Liren, Li, Qi, Zuo, Tao, Cohen-Kedar, Sarit, Lu, Jiawei, Ardy, Rico Chandra, Mulder, Daniel J., Dissanayake, Dilan, Peng, Kaiyue, Huang, Zhiheng, Li, Xiaoqin, Wang, Yuesheng, Wang, Xiaobing, Li, Shuchao, Bullers, Samuel, Gammage, Anís N., Warnatz, Klaus, Schiefer, Ana-Iris, Krivan, Gergely, Goda, Vera, Kahr, Walter H.A., Lemaire, Mathieu, Lu, Chien-Yi, Siddiqui, Iram, Surette, Michael G., Kotlarz, Daniel, Engelhardt, Karin R., Griffin, Helen R., Rottapel, Robert, Decaluwe, Hélène, Laxer, Ronald M., Proietti, Michele, Hambleton, Sophie, Elcombe, Suzanne, Guo, Cong-Hui, Grimbacher, Bodo, Dotan, Iris, Ng, Siew C., Freeman, Spencer A., Snapper, Scott B., Klein, Christoph, Boztug, Kaan, Huang, Ying, Li, Dali, Uhlig, Holm H., Muise, Aleixo M.
Publicado 2021