An Adaptive Biosystems Engineering Approach towards Modeling the Soluble-to-Insoluble Phase Transition of Clofazimine

por Willmer, Andrew R., Dunne, Steven, Swanson, Rosemary, Almeida, Deepak, Ammerman, Nicole C., Stringer, Kathleen A., Capparelli, Edmund V., Rosania, Gus R.
Publicado 2021

Quantitative Analysis of the Phase Transition Mechanism Underpinning the Systemic Self-Assembly of a Mechanopharmaceutical Device

por Dunne, Steven, Willmer, Andrew R., Swanson, Rosemary, Almeida, Deepak, Ammerman, Nicole C., Stringer, Kathleen A., Capparelli, Edmund V., Rosania, Gus R.
Publicado 2021

Population Pharmacokinetics and Dosing Optimization of Vancomycin in Pediatric Liver Transplant Recipients

por Shoji, Kensuke, Saito, Jumpei, Nakagawa, Hidenori, Funaki, Takanori, Fukuda, Akinari, Sakamoto, Seisuke, Kasahara, Mureo, Momper, Jeremiah D., Capparelli, Edmund V., Miyairi, Isao
Publicado 2021

Sertraline Pharmacokinetics in HIV-Infected and Uninfected Children, Adolescents, and Young Adults

por Hanan, Nathan John, Paul, Mary Elizabeth, Huo, Yanling, Kapetanovic, Suad, Smith, Elizabeth, Siberry, George, Brouwers, Pim, Graham, Bobbie, Johnston, Benjamin, Capparelli, Edmund V., Best, Brookie M.
Publicado 2019

Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum

por Bustinduy, Amaya L., Kolamunnage-Dona, Ruwanthi, Mirochnick, Mark H., Capparelli, Edmund V., Tallo, Veronica, Acosta, Luz P., Olveda, Remigio M., Friedman, Jennifer F., Hope, William W.
Publicado 2020

Physiologically‐based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID‐19

por Liu, Xiaomei I., Dallmann, André, Brooks, Kristina, Best, Brookie M., Clarke, Diana F., Mirochnick, Mark, van den Anker, John N., Capparelli, Edmund V., Momper, Jeremiah D.
Publicado 2022

Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development

por Zhao, Sherry, Gockenbach, Mary, Grimstein, Manuela, Sachs, Hari Cheryl, Mirochnick, Mark, Struble, Kimberly, Belew, Yodit, Wang, Jian, Capparelli, Edmund V., Best, Brookie M., Johnson, Tamara, Momper, Jeremiah D., Maharaj, Anil R.
Publicado 2021

A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria

por Birbeck, Gretchen L., Herman, Susan T., Capparelli, Edmund V., Dzinjalamala, Fraction K., Abdel Baki, Samah G., Mallewa, Macpherson, Toto, Neema M., Postels, Douglas G., Gardiner, Joseph C., Taylor, Terrie E., Seydel, Karl B.
Publicado 2019

Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life

por Maswabi, Kenneth, Ajibola, Gbolahan, Bennett, Kara, Capparelli, Edmund V, Jean-Philippe, Patrick, Moyo, Sikhulile, Mohammed, Terence, Batlang, Oganne, Sakoi, Maureen, Lockman, Shahin, Makhema, Joseph, Lichterfeld, Mathias, Kuritzkes, Daniel R, Hughes, Michael D, Shapiro, Roger L
Publicado 2020

Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa...

por Onyamboko, Marie A, Meshnick, Steven R, Fleckenstein, Lawrence, Koch, Matthew A, Atibu, Joseph, Lokomba, Victor, Douoguih, Macaya, Hemingway-Foday, Jennifer, Wesche, David, Ryder, Robert W, Bose, Carl, Wright, Linda L, Tshefu, Antoinette K, Capparelli, Edmund V
Publicado 2011

Etravirine Pharmacokinetics in HIV-Infected Pregnant Women

por Mulligan, Nikki, Schalkwijk, Stein, Best, Brookie M., Colbers, Angela, Wang, Jiajia, Capparelli, Edmund V., Moltó, José, Stek, Alice M., Taylor, Graham, Smith, Elizabeth, Hidalgo Tenorio, Carmen, Chakhtoura, Nahida, van Kasteren, Marjo, Fletcher, Courtney V., Mirochnick, Mark, Burger, David
Publicado 2016

Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement

por Eke, Ahizechukwu C., Olagunju, Adeniyi, Momper, Jeremiah, Penazzato, Martina, Abrams, Elaine J., Best, Brookie M., Capparelli, Edmund V., Bekker, Adrie, Belew, Yodit, Kiser, Jennifer J., Struble, Kimberly, Taylor, Graham, Waitt, Catriona, Mirochnick, Mark, Cressey, Tim R., Colbers, Angela
Publicado 2020

Low‐dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial

por Naviaux, Robert K., Curtis, Brooke, Li, Kefeng, Naviaux, Jane C., Bright, A. Taylor, Reiner, Gail E., Westerfield, Marissa, Goh, Suzanne, Alaynick, William A., Wang, Lin, Capparelli, Edmund V., Adams, Cynthia, Sun, Ji, Jain, Sonia, He, Feng, Arellano, Deyna A., Mash, Lisa E., Chukoskie, Leanne, Lincoln, Alan, Townsend, Jeanne
Publicado 2017

Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol

por Cafferata, María L., Toscani, María A., Althabe, Fernando, Belizán, Jose M., Bergel, Eduardo, Berrueta, Mabel, Capparelli, Edmund V., Ciganda, Álvaro, Danesi, Emmaria, Dumonteil, Eric, Gibbons, Luz, Gulayin, Pablo E., Herrera, Claudia, Momper, Jeremiah D., Rossi, Steven, Shaffer, Jeffrey G., Schijman, Alejandro G., Sosa-Estani, Sergio, Stella, Candela B., Klein, Karen, Buekens, Pierre
Publicado 2020

Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention

por Mahomed, Sharana, Garrett, Nigel, Capparelli, Edmund V, Osman, Farzana, Harkoo, Ishana, Yende-Zuma, Nonhlanhla, Gengiah, Tanuja N, Archary, Derseree, Samsunder, Natasha, Baxter, Cheryl, Mkhize, Nonhlanhla N, Modise, Tandile, Carlton, Kevin, McDermott, Adrian, Moore, Penny L, Karim, Quarraisha Abdool, Barouch, Dan H, Fast, Patricia E, Mascola, John R, Ledgerwood, Julie E, Morris, Lynn, Abdool Karim, Salim S
Publicado 2022

Population Pharmacokinetics and Exploratory Exposure‐Response Relationships of Diazepam in Children Treated for Status Epilepticus

por Ku, Lawrence C., Hornik, Christoph P., Beechinor, Ryan J., Chamberlain, James M., Guptill, Jeffrey T., Harper, Barrie, Capparelli, Edmund V., Martz, Karen, Anand, Ravinder, Cohen‐Wolkowiez, Michael, Gonzalez, Daniel, Furda, Gary, Benjamin, Danny, Kearns, Gregory L., Paul, Ian M., Sullivan, Jan, Hornik, Christoph P., Wade, Kelly, Siegel, David, Taylor‐Zapata, Perdita, Zajicek, Anne, Ren, Zhaoxia, Tsilou, Ekaterini, Pagan, Alice, Simone, Gina, Ku, Lawrence, Mills, Mary, Watt, Kevin
Publicado 2018