Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation

por Akef, Abdalla, McGraw, Kathy, Cappell, Steven D., Larson, Daniel R.
Publicado 2020

Cell cycle inertia underlies a bifurcation in cell fates after DNA damage

por Nathans, Jenny F., Cornwell, James A., Afifi, Marwa M., Paul, Debasish, Cappell, Steven D.
Publicado 2021

Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

por Cornwell, James A., Crncec, Adrijana, Afifi, Marwa M., Tang, Kristina, Amin, Ruhul, Cappell, Steven D.
Publicado 2023

Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor

por Paul, Debasish, Kales, Stephen C., Cornwell, James A., Afifi, Marwa M., Rai, Ganesha, Zakharov, Alexey, Simeonov, Anton, Cappell, Steven D.
Publicado 2022

Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targe6ng of WRN and ATR

por Zong, Dali, Koussa, Natasha C., Cornwell, James A., Pankajam, Ajith V., Kruhlak, Michael J., Wong, Nancy, Chari, Raj, Cappell, Steven D., Nussenzweig, André
Publicado 2023

The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity

por Awadia, Sahezeel, Sitto, Merna, Ram, Sundaresh, Ji, Wenbin, Liu, Yajing, Damani, Raheema, Ray, Dipankar, Lawrence, Theodore S., Galban, Craig J., Cappell, Steven D., Rehemtulla, Alnawaz
Publicado 2023

Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation

por Afifi, Marwa M., Crncec, Adrijana, Cornwell, James A., Cataisson, Christophe, Paul, Debasish, Ghorab, Laila M., Hernandez, Maria O., Wong, Madeline, Kedei, Noemi, Cappell, Steven D.
Publicado 2023

Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation

por Yang, Hee Won, Cappell, Steven D, Jaimovich, Ariel, Liu, Chad, Chung, Mingyu, Daigh, Leighton H, Pack, Lindsey R, Fan, Yilin, Regot, Sergi, Covert, Markus, Meyer, Tobias
Publicado 2020

Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway

por Park, Woo-Yong, Gray, Justin M., Holewinski, Ronald J., Andresson, Thorkell, So, Jae Young, Carmona-Rivera, Carmelo, Hollander, M. Christine, Yang, Howard H., Lee, Maxwell, Kaplan, Mariana J., Cappell, Steven D., Yang, Li
Publicado 2023

The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation

por Jang, Sang-Min, Nathans, Jenny F., Fu, Haiqing, Redon, Christophe E., Jenkins, Lisa M., Thakur, Bhushan L., Pongor, Lőrinc S., Baris, Adrian M., Gross, Jacob M., OʹNeill, Maura J., Indig, Fred E., Cappell, Steven D., Aladjem, Mirit I.
Publicado 2020

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

por Amin, Ruhul, Shukla, Anjali, Zhu, Jacqueline Jufen, Kim, Sohyoung, Wang, Ping, Tian, Simon Zhongyuan, Tran, Andy D., Paul, Debasish, Cappell, Steven D., Burkett, Sandra, Liu, Huaitian, Lee, Maxwell P., Kruhlak, Michael J., Dwyer, Jennifer E., Simpson, R. Mark, Hager, Gordon L., Ruan, Yijun, Hunter, Kent W.
Publicado 2021