2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase

por Matheson, Christopher J., Coxon, Christopher R., Bayliss, Richard, Boxall, Kathy, Carbain, Benoit, Fry, Andrew M., Hardcastle, Ian R., Harnor, Suzannah J., Mas-Droux, Corine, Newell, David R., Richards, Mark W., Sivaprakasam, Mangaleswaran, Turner, David, Griffin, Roger J., Golding, Bernard T., Cano, Céline
Publicado 2020

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines

por Coxon, Christopher R., Anscombe, Elizabeth, Harnor, Suzannah J., Martin, Mathew P., Carbain, Benoit, Golding, Bernard T., Hardcastle, Ian R., Harlow, Lisa K., Korolchuk, Svitlana, Matheson, Christopher J., Newell, David R., Noble, Martin E. M., Sivaprakasam, Mangaleswaran, Tudhope, Susan J., Turner, David M., Wang, Lan Z., Wedge, Stephen R., Wong, Christopher, Griffin, Roger J., Endicott, Jane A., Cano, Céline
Publicado 2016