UCP2-dependent redox sensing in POMC neurons regulates feeding

por Yoon, Nal Ae, Jin, Sungho, Kim, Jung Dae, Liu, Zhong Wu, Sun, Qiushi, Cardone, Rebecca, Kibbey, Richard, Diano, Sabrina
Publicado 2022

Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats

por Perry, Rachel J., Rabin-Court, Aviva, Song, Joongyu D., Cardone, Rebecca L., Wang, Yongliang, Kibbey, Richard G., Shulman, Gerald I.
Publicado 2019

Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis

por Davis, Jeffrey C., Alves, Tiago C., Helman, Aharon, Chen, Jonathan C., Kenty, Jennifer H., Cardone, Rebecca L., Liu, David R., Kibbey, Richard G., Melton, Douglas A.
Publicado 2020

Acetate mediates a microbiome-brain-β cell axis promoting metabolic syndrome

por Perry, Rachel J., Peng, Liang, Barry, Natasha A., Cline, Gary W., Zhang, Dongyan, Cardone, Rebecca L., Petersen, Kitt Falk, Kibbey, Richard G., Goodman, Andrew L., Shulman, Gerald I.
Publicado 2016

Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice

por Bhat, Neha, Narayanan, Anand, Fathzadeh, Mohsen, Kahn, Mario, Zhang, Dongyan, Goedeke, Leigh, Neogi, Arpita, Cardone, Rebecca L., Kibbey, Richard G., Fernandez-Hernando, Carlos, Ginsberg, Henry N., Jain, Dhanpat, Shulman, Gerald I., Mani, Arya
Publicado 2022

β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the K(ATP) channel

por Foster, Hannah R, Ho, Thuong, Potapenko, Evgeniy, Sdao, Sophia M, Huang, Shih Ming, Lewandowski, Sophie L, VanDeusen, Halena R, Davidson, Shawn M, Cardone, Rebecca L, Prentki, Marc, Kibbey, Richard G, Merrins, Matthew J
Publicado 2022

CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation

por Esteghamat, Fatemehsadat, Broughton, James S., Smith, Emily, Cardone, Rebecca, Tyagi, Tarun, Guerra, Mateus, Szabó, András, Ugwu, Nelson, Mani, Mitra V., Azari, Bani, Kayingo, Gerald, Chung, Sunny, Fathzadeh, Mohsen, Weiss, Ephraim, Bender, Jeffrey, Mane, Shrikant, Lifton, Richard P., Adeniran, Adebowale, Nathanson, Michael H., Gorelick, Fred S., Hwa, John, Sahin-Tóth, Miklós, Belfort-DeAguiar, Renata, Kibbey, Richard G., Mani, Arya
Publicado 2019

β Cell–specific deletion of Zfp148 improves nutrient-stimulated β cell Ca(2+) responses

por Emfinger, Christopher H., de Klerk, Eleonora, Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donnie S., Simonett, Shane P., Mitok, Kelly A., Wang, Ziyue, Liu, Xinyue, Paulo, Joao A., Yu, Qing, Cardone, Rebecca L., Foster, Hannah R., Lewandowski, Sophie L., Perales, José C., Kendziorski, Christina M., Gygi, Steven P., Kibbey, Richard G., Keller, Mark P., Hebrok, Matthias, Merrins, Matthew J., Attie, Alan D.
Publicado 2022