Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response

por Reshkin, Stephan J., Cardone, Rosa Angela
Publicado 2020

Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment

por Altamura, Concetta, Greco, Maria Raffaella, Carratù, Maria Rosaria, Cardone, Rosa Angela, Desaphy, Jean-François
Publicado 2021

Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway

por Greco, Maria Raffaella, Moro, Loredana, Forciniti, Stefania, Alfarouk, Khalid, Cannone, Stefania, Cardone, Rosa Angela, Reshkin, Stephan Joel
Publicado 2021

The Na(+)–H(+ )exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

por Paradiso, Angelo, Cardone, Rosa Angela, Bellizzi, Antonia, Bagorda, Anna, Guerra, Lorenzo, Tommasino, Massimo, Casavola, Valeria, Reshkin, Stephan J
Publicado 2004

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs – an integral molecular/biochemical/metabolic/clinical approach after one hundred ye...

por Harguindey, Salvador, Arranz, Jose Luis, Polo Orozco, Julian David, Rauch, Cyril, Fais, Stefano, Cardone, Rosa Angela, Reshkin, Stephan J
Publicado 2013

Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma: A Physiopathologic and Pharmacologic Review

por Koltai, Tomas, Reshkin, Stephan Joel, Carvalho, Tiago M. A., Di Molfetta, Daria, Greco, Maria Raffaella, Alfarouk, Khalid Omer, Cardone, Rosa Angela
Publicado 2022

Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell

por Tavares-Valente, Diana, Cannone, Stefania, Greco, Maria Raffaella, Carvalho, Tiago Miguel Amaral, Baltazar, Fátima, Queirós, Odília, Agrimi, Gennaro, Reshkin, Stephan J., Cardone, Rosa Angela
Publicado 2023

Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension

por Carratu, Pierluigi, Scoditti, Cristina, Maniscalco, Mauro, Seccia, Teresa Maria, Di Gioia, Giuseppe, Gadaleta, Felice, Cardone, Rosa Angela, Dragonieri, Silvano, Pierucci, Paola, Spanevello, Antonio, Resta, Onofrio
Publicado 2008

Cancer Associated Fibroblast (CAF) Regulation of PDAC Parenchymal (CPC) and CSC Phenotypes Is Modulated by ECM Composition

por Cannone, Stefania, Greco, Maria Raffaella, Carvalho, Tiago M. A., Guizouarn, Helene, Soriani, Olivier, Di Molfetta, Daria, Tomasini, Richard, Zeeberg, Katrine, Reshkin, Stephan Joel, Cardone, Rosa Angela
Publicado 2022

Na(+)/H(+) Exchanger Regulatory Factor 1 Overexpression-dependent Increase of Cytoskeleton Organization Is Fundamental in the Rescue of F508del Cystic Fibrosis Transmembrane Conduc...

por Favia, Maria, Guerra, Lorenzo, Fanelli, Teresa, Cardone, Rosa Angela, Monterisi, Stefania, Di Sole, Francesca, Castellani, Stefano, Chen, Mingmin, Seidler, Ursula, Reshkin, Stephan Joel, Conese, Massimo, Casavola, Valeria
Publicado 2010

The Role of Sodium Hydrogen Exchanger 1 in Dysregulation of Proton Dynamics and Reprogramming of Cancer Metabolism as a Sequela

por Cardone, Rosa Angela, Alfarouk, Khalid Omer, Elliott, Robert L., Alqahtani, Saad Saeed, Ahmed, Samrein B. M., Aljarbou, Ahmed N., Greco, Maria Raffaella, Cannone, Stefania, Reshkin, Stephan Joel
Publicado 2019

Upregulation of YKL-40 Promotes Metastatic Phenotype and Correlates with Poor Prognosis and Therapy Response in Patients with Colorectal Cancer

por De Robertis, Mariangela, Greco, Maria Raffaella, Cardone, Rosa Angela, Mazza, Tommaso, Marzano, Flaviana, Mehterov, Nikolay, Kazakova, Maria, Belev, Nikolay, Tullo, Apollonia, Pesole, Graziano, Sarafian, Victoria, Signori, Emanuela
Publicado 2022

Combined Dopamine and Grape Seed Extract-Loaded Solid Lipid Nanoparticles: Nasal Mucosa Permeation, and Uptake by Olfactory Ensheathing Cells and Neuronal SH-SY5Y Cells †

por Trapani, Adriana, Castellani, Stefano, Guerra, Lorenzo, De Giglio, Elvira, Fracchiolla, Giuseppe, Corbo, Filomena, Cioffi, Nicola, Passantino, Giuseppe, Poeta, Maria Luana, Montemurro, Pasqualina, Mallamaci, Rosanna, Cardone, Rosa Angela, Conese, Massimo
Publicado 2023

A Novel NHE1-Centered Signaling Cassette Drives Epidermal Growth Factor Receptor–Dependent Pancreatic Tumor Metastasis and Is a Target for Combination Therapy()

por Cardone, Rosa Angela, Greco, Maria Raffaella, Zeeberg, Katrine, Zaccagnino, Angela, Saccomano, Mara, Bellizzi, Antonia, Bruns, Philipp, Menga, Marta, Pilarsky, Christian, Schwab, Albrecht, Alves, Frauke, Kalthoff, Holger, Casavola, Valeria, Reshkin, Stephan Joel
Publicado 2015

ECM Composition Differentially Regulates Intracellular and Extracellular pH in Normal and Cancer Pancreatic Duct Epithelial Cells

por Di Molfetta, Daria, Cannone, Stefania, Greco, Maria Raffaella, Caroppo, Rosa, Piccapane, Francesca, Carvalho, Tiago Miguel Amaral, Altamura, Concetta, Saltarella, Ilaria, Tavares Valente, Diana, Desaphy, Jean Francois, Reshkin, Stephan J., Cardone, Rosa Angela
Publicado 2023

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

por Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Adil, H. H Bashir, Elhassan, Gamal O., Ibrahim, Muntaser E., David Polo Orozco, Julian, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Publicado 2014

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

por Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Bashir, Adil H. H., Elhassan, Gamal O., Ibrahim, Muntaser E., Orozco, Julian David Polo, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Publicado 2014

NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains

por Cardone, Rosa Angela, Greco, Maria Raffaella, Capulli, Mattia, Weinman, Edward J., Busco, Giovanni, Bellizzi, Antonia, Casavola, Valeria, Antelmi, Ester, Ambruosi, Barbara, Dell'Aquila, Maria Elena, Paradiso, Angelo, Teti, Anna, Rucci, Nadia, Reshkin, Stephan Joel
Publicado 2012

Acidic Growth Conditions Promote Epithelial-to-Mesenchymal Transition to Select More Aggressive PDAC Cell Phenotypes In Vitro

por Audero, Madelaine Magalì, Carvalho, Tiago Miguel Amaral, Ruffinatti, Federico Alessandro, Loeck, Thorsten, Yassine, Maya, Chinigò, Giorgia, Folcher, Antoine, Farfariello, Valerio, Amadori, Samuele, Vaghi, Chiara, Schwab, Albrecht, Reshkin, Stephan J., Cardone, Rosa Angela, Prevarskaya, Natalia, Fiorio Pla, Alessandra
Publicado 2023

Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine

por Forciniti, Stefania, Dalla Pozza, Elisa, Greco, Maria Raffaella, Amaral Carvalho, Tiago Miguel, Rolando, Barbara, Ambrosini, Giulia, Carmona-Carmona, Cristian Andres, Pacchiana, Raffaella, Di Molfetta, Daria, Donadelli, Massimo, Arpicco, Silvia, Palmieri, Marta, Reshkin, Stephan Joel, Dando, Ilaria, Cardone, Rosa Angela
Publicado 2020