Return of the Neurotropic Enteroviruses: Co-Opting Cellular Pathways for Infection

por Peters, Christine E., Carette, Jan E.
Publicado 2021

A CRISPR toolbox to study virus–host interactions

por Puschnik, Andreas S., Majzoub, Karim, Ooi, Yaw Shin, Carette, Jan E.
Publicado 2017

A Reporter Screen in a Human Haploid Cell Line Identifies CYLD as a Constitutive Inhibitor of NF-κB

por Lee, Clarissa C., Carette, Jan E., Brummelkamp, Thijn R., Ploegh, Hidde L.
Publicado 2013

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens

por Patel, Bhaven B., Lebensohn, Andres M., Pusapati, Ganesh V., Carette, Jan E., Salzman, Julia, Rohatgi, Rajat
Publicado 2019

Differential and convergent utilization of autophagy components by positive-strand RNA viruses

por Abernathy, Emma, Mateo, Roberto, Majzoub, Karim, van Buuren, Nick, Bird, Sara W., Carette, Jan E., Kirkegaard, Karla
Publicado 2019

Loquacious modulates flaviviral RNA replication in mosquito cells

por Shivaprasad, Shwetha, Weng, Kuo-Feng, Ooi, Yaw Shin, Belk, Julia, Carette, Jan E., Flynn, Ryan, Sarnow, Peter
Publicado 2022

Identification of host cell factors required for intoxication through use of modified cholera toxin

por Guimaraes, Carla P., Carette, Jan E., Varadarajan, Malini, Antos, John, Popp, Maximilian W., Spooner, Eric, Brummelkamp, Thijn R., Ploegh, Hidde L.
Publicado 2011

Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C

por Ay, Ferhat, Vu, Thanh H, Zeitz, Michael J, Varoquaux, Nelle, Carette, Jan E, Vert, Jean-Philippe, Hoffman, Andrew R, Noble, William S
Publicado 2015

Lipid droplets can promote drug accumulation and activation

por Dubey, Ramin, Stivala, Craig E, Nguyen, Huy Quoc, Goo, Young-Hwa, Paul, Antoni, Carette, Jan E, Trost, Barry M, Rohatgi, Rajat
Publicado 2020

Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism

por Liu, Qi, Gupta, Amita, Okesli-Armlovich, Ayse, Qiao, Wenjie, Fischer, Curt R., Smith, Mark, Carette, Jan E., Bassik, Michael C., Khosla, Chaitan
Publicado 2020

Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation

por Song, Yanhua, Hou, Gaopeng, Diep, Jonathan, Ooi, Yaw Shin, Akopyants, Natalia S, Beverley, Stephen M, Carette, Jan E, Greenberg, Harry B, Ding, Siyuan
Publicado 2021

Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus

por Baggen, Jim, Thibaut, Hendrik Jan, Hurdiss, Daniel L., Wahedi, Maryam, Marceau, Caleb D., van Vliet, Arno L. W., Carette, Jan E., van Kuppeveld, Frank J. M.
Publicado 2019

Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread

por Realegeno, Susan, Priyamvada, Lalita, Kumar, Amrita, Blackburn, Jessica B., Hartloge, Claire, Puschnik, Andreas S., Sambhara, Suryaprakash, Olson, Victoria A., Carette, Jan E., Lupashin, Vladimir, Satheshkumar, Panayampalli Subbian
Publicado 2020

Complement pathway amplifies caspase-11–dependent cell death and endotoxin-induced sepsis severity

por Napier, Brooke A., Brubaker, Sky W., Sweeney, Timothy E., Monette, Patrick, Rothmeier, Greggory H., Gertsvolf, Nina A., Puschnik, Andreas, Carette, Jan E., Khatri, Purvesh, Monack, Denise M.
Publicado 2016

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

por Marceau, Caleb D., Puschnik, Andreas S., Majzoub, Karim, Ooi, Yaw Shin, Brewer, Susan M., Fuchs, Gabriele, Swaminathan, Kavya, Mata, Miguel A., Elias, Joshua E., Sarnow, Peter, Carette, Jan E.
Publicado 2016

GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry

por Hartmann, Jessica, Thalheimer, Frederic B., Höpfner, Felix, Kerzel, Thomas, Khodosevich, Konstantin, García-González, Diego, Monyer, Hannah, Diester, Ilka, Büning, Hildegard, Carette, Jan E., Fries, Pascal, Buchholz, Christian J.
Publicado 2019

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

por Ndungo, Esther, Herbert, Andrew S., Raaben, Matthijs, Obernosterer, Gregor, Biswas, Rohan, Miller, Emily Happy, Wirchnianski, Ariel S., Carette, Jan E., Brummelkamp, Thijn R., Whelan, Sean P., Dye, John M., Chandran, Kartik
Publicado 2016

Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1

por Guo, Hongyan, Gilley, Ryan P., Fisher, Amanda, Lane, Rebecca, Landsteiner, Vanessa J., Ragan, Katherine B., Dovey, Cole M., Carette, Jan E., Upton, Jason W., Mocarski, Edward S., Kaiser, William J.
Publicado 2018

The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation

por Wąhalska, Magda, Riepe, Celeste, Ślusarz, Magdalena J., Graul, Małgorzata, Borowski, Lukasz S., Qiao, Wenjie, Foltynska, Michalina, Carette, Jan E., Bieńkowska-Szewczyk, Krystyna, Szczesny, Roman J., Kopito, Ron R., Lipińska, Andrea D.
Publicado 2023

Global gene disruption in human cells to assign genes to phenotypes

por Carette, Jan E., Guimaraes, Carla P., Wuethrich, Irene, Blomen, Vincent A., Varadarajan, Malini, Sun, Chong, Bell, George, Yuan, Bingbing, Muellner, Markus K., Nijman, Sebastian M., Ploegh, Hidde L., Brummelkamp, Thijn R.
Publicado 2011