Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

por Carlile, Thomas M., Rojas-Duran, Maria F., Zinshteyn, Boris, Shin, Hakyung, Bartoli, Kristen M., Gilbert, Wendy V.
Publicado 2014

mRNA structure determines modification by pseudouridine synthase 1

por Carlile, Thomas M., Martinez, Nicole M., Schaening, Cassandra, Su, Amanda, Bell, Tristan A., Zinshteyn, Boris, Gilbert, Wendy V.
Publicado 2019

Aneuploid yeast strains exhibit defects in cell growth and passage through START

por Thorburn, Rebecca R., Gonzalez, Christian, Brar, Gloria A., Christen, Stefan, Carlile, Thomas M., Ingolia, Nicholas T., Sauer, Uwe, Weissman, Jonathan S., Amon, Angelika
Publicado 2013

SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures

por Nicholatos, Justin W., Groot, Joost, Dhokai, Shekhar, Tran, David, Hrdlicka, Lori, Carlile, Thomas M., Bennion, Melissa, Dalkilic-Liddle, Isin, Hirst, Warren D., Weihofen, Andreas
Publicado 2021

Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

por Delbridge, Alex R. D., Huh, Dann, Brickelmaier, Margot, Burns, Jeremy C., Roberts, Chris, Challa, Ravi, Raymond, Naideline, Cullen, Patrick, Carlile, Thomas M., Ennis, Katelin A., Liu, Mei, Sun, Chao, Allaire, Normand E., Foos, Marianna, Tsai, Hui-Hsin, Franchimont, Nathalie, Ransohoff, Richard M., Butts, Cherie, Mingueneau, Michael
Publicado 2020

Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection

por Chen, Shukkwan K., Hawley, Zachary C.E., Zavodszky, Maria I., Hana, Sam, Ferretti, Daniel, Grubor, Branka, Hawes, Michael, Xu, Shanqin, Hamann, Stefan, Marsh, Galina, Cullen, Patrick, Challa, Ravi, Carlile, Thomas M., Zhang, Hang, Lee, Wan-Hung, Peralta, Andrea, Clarner, Pete, Wei, Cong, Koszka, Kathryn, Gao, Feng, Lo, Shih-Ching
Publicado 2023

Next‐generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells...

por Bame, Eris, Tang, Hao, Burns, Jeremy C, Arefayene, Million, Michelsen, Klaus, Ma, Bin, Marx, Isaac, Prince, Robin, Roach, Allie M, Poreci, Urjana, Donaldson, Douglas, Cullen, Patrick, Casey, Fergal, Zhu, Jing, Carlile, Thomas M, Sangurdekar, Dipen, Zhang, Baohong, Trapa, Patrick, Santoro, Joseph, Muragan, Param, Pellerin, Alex, Rubino, Stephen, Gianni, Davide, Bajrami, Bekim, Peng, Xiaomei, Coppell, Alex, Riester, Katherine, Belachew, Shibeshih, Mehta, Devangi, Palte, Mike, Hopkins, Brian T, Scaramozza, Matthew, Franchimont, Nathalie, Mingueneau, Michael
Publicado 2021

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model

por Chen, Yi A., Kankel, Mark W., Hana, Sam, Lau, Shukkwan Kelly, Zavodszky, Maria I., McKissick, Olivia, Mastrangelo, Nicole, Dion, Jessica, Wang, Bin, Ferretti, Daniel, Koske, David, Lehman, Sydney, Koszka, Kathryn, McLaughlin, Helen, Liu, Mei, Marshall, Eric, Fabian, Attila J., Cullen, Patrick, Marsh, Galina, Hamann, Stefan, Craft, Michael, Sebalusky, Jennifer, Arnold, H. Moore, Driscoll, Rachelle, Sheehy, Adam, Luo, Yi, Manca, Sonia, Carlile, Thomas, Sun, Chao, Sigrist, Kirsten, McCampbell, Alexander, Henderson, Christopher E., Lo, Shih-Ching
Publicado 2022

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis

por Lafaille, Fabien G., Harschnitz, Oliver, Lee, Yoon Seung, Zhang, Peng, Hasek, Mary L., Kerner, Gaspard, Itan, Yuval, Ewaleifoh, Osefame, Rapaport, Franck, Carlile, Thomas M., Carter-Timofte, Madalina E., Paquet, Dominik, Dobbs, Kerry, Zimmer, Bastian, Gao, Daxing, Rojas-Duran, Maria F., Kwart, Dylan, Rattina, Vimel, Ciancanelli, Michael J., McAlpine, Jessica L., Lorenzo, Lazaro, Boucherit, Soraya, Rozenberg, Flore, Halwani, Rabih, Henry, Benoit, Amenzoui, Naima, Alsum, Zobaida, Marques, Laura, Church, Joseph A., Al-Muhsen, Saleh, Tardieu, Marc, Bousfiha, Ahmed Aziz, Paludan, Søren R., Mogensen, Trine Hyrup, Quintana-Murci, Lluis, Tessier-Lavigne, Marc, Smith, Gregory A., Notarangelo, Luigi D., Studer, Lorenz, Gilbert, Wendy, Abel, Laurent, Casanova, Jean-Laurent, Zhang, Shen-Ying
Publicado 2019