Pharmacogenomics: Current State-of-the-Art

por Carr, Daniel F., Alfirevic, Ana, Pirmohamed, Munir
Publicado 2014

Critical assessment of approaches for molecular docking to elucidate associations of HLA alleles with adverse drug reactions

por Ramsbottom, Kerry A., Carr, Daniel F., Jones, Andrew R., Rigden, Daniel J.
Publicado 2018

Informatics investigations into anti-thyroid drug induced agranulocytosis associated with multiple HLA-B alleles

por Ramsbottom, Kerry A., Carr, Daniel F., Rigden, Daniel J., Jones, Andrew R.
Publicado 2020

Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression

por Parry, Christopher M., Chan, Li F., Carr, Daniel F., Hawcutt, Daniel B.
Publicado 2022

CYP3A genetic variation and taxane-induced peripheral neuropathy: a systematic review, meta-analysis, and candidate gene study

por McEvoy, Laurence, Cliff, Joanne, Carr, Daniel F, Jorgensen, Andrea, Lord, Rosemary, Pirmohamed, Munir
Publicado 2023

Corrigendum: CYP3A genetic variation and taxane-induced peripheral neuropathy: a systematic review, meta-analysis, and candidate gene study

por McEvoy, Laurence, Cliff, Joanne, Carr, Daniel F, Jorgensen, Andrea, Lord, Rosemary, Pirmohamed, Munir
Publicado 2023

Electronic health records for biological sample collection: feasibility study of statin-induced myopathy using the Clinical Practice Research Datalink

por O'Meara, Helen, Carr, Daniel F, Evely, Jane, Hobbs, Mark, McCann, Gerard, van Staa, Tjeerd, Pirmohamed, Munir
Publicado 2014

Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine

por Yip, Vincent L.M., Pertinez, Henry, Meng, Xiaoli, Maggs, James L., Carr, Daniel F., Park, B. Kevin, Marson, Anthony G., Pirmohamed, Munir
Publicado 2020

Population Pharmacokinetic and Pharmacogenetic Analysis of Nevirapine in Hypersensitive and Tolerant HIV-Infected Patients from Malawi

por Dickinson, Laura, Chaponda, Masautso, Carr, Daniel F., van Oosterhout, Joep J., Kumwenda, Johnstone, Lalloo, David G., Pirmohamed, Munir, Heyderman, Robert S., Khoo, Saye H.
Publicado 2014

Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population

por Carr, Daniel F., Chaponda, Mas, Jorgensen, Andrea L., Castro, Elena Cornejo, van Oosterhout, Joep J., Khoo, Saye H., Lalloo, David G., Heyderman, Robert S., Alfirevic, Ana, Pirmohamed, Munir
Publicado 2013

Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration

por Bourgeois, Stephane, Carr, Daniel F., Musumba, Crispin O., Penrose, Alexander, Esume, Celestine, Morris, Andrew P., Jorgensen, Andrea L., Zhang, J. Eunice, Pritchard, D. Mark, Deloukas, Panos, Pirmohamed, Munir
Publicado 2021

CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations

por Carr, Daniel F., Chaponda, Mas, Cornejo Castro, Elena M., Jorgensen, Andrea L., Khoo, Saye, Van Oosterhout, Joep J., Dandara, Collet, Kampira, Elizabeth, Ssali, Francis, Munderi, Paula, Lalloo, David G., Heyderman, Robert S., Pirmohamed, Munir
Publicado 2014

Software for Dosage Individualization of Voriconazole: a Prospective Clinical Study

por Hope, William, Johnstone, Gary, Cicconi, Silvia, Felton, Timothy, Goodwin, Joanne, Whalley, Sarah, Santoyo-Castelazo, Anahi, Ramos-Martin, Virginia, Lestner, Jodi, Credidio, Leah, Dane, Aaron, Carr, Daniel F., Pirmohamed, Munir, Salim, Rahim, Neely, Michael
Publicado 2019

Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with CYP2B6 c.516G→T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis

por Nightingale, Sam, Chau, Tran Thi Hong, Fisher, Martin, Nelson, Mark, Winston, Alan, Else, Laura, Carr, Daniel F., Taylor, Steven, Ustianowski, Andrew, Back, David, Pirmohamed, Munir, Solomon, Tom, Farrar, Jeremy, Törok, M. Estée, Khoo, Saye
Publicado 2016

Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

por Carr, Daniel F., Francis, Ben, Jorgensen, Andrea L., Zhang, Eunice, Chinoy, Hector, Heckbert, Susan R., Bis, Joshua C., Brody, Jennifer A., Floyd, James S., Psaty, Bruce M., Molokhia, Mariam, Lapeyre‐Mestre, Maryse, Conforti, Anita, Alfirevic, Ana, van Staa, Tjeerd, Pirmohamed, Munir
Publicado 2019

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

por Hawcutt, Daniel B, Francis, Ben, Carr, Daniel F, Jorgensen, Andrea L, Yin, Peng, Wallin, Naomi, O'Hara, Natalie, Zhang, Eunice J, Bloch, Katarzyna M, Ganguli, Amitava, Thompson, Ben, McEvoy, Laurence, Peak, Matthew, Crawford, Andrew A, Walker, Brian R, Blair, Joanne C, Couriel, Jonathan, Smyth, Rosalind L, Pirmohamed, Munir
Publicado 2018

Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population

por Carr, Daniel F., Bourgeois, Stephane, Chaponda, Mas, Takeshita, Louise Y., Morris, Andrew P., Castro, Elena M. Cornejo, Alfirevic, Ana, Jones, Andrew R., Rigden, Daniel J., Haldenby, Sam, Khoo, Saye, Lalloo, David G., Heyderman, Robert S., Dandara, Collet, Kampira, Elizabeth, van Oosterhout, Joep J., Ssali, Francis, Munderi, Paula, Novelli, Giuseppe, Borgiani, Paola, Nelson, Matthew R., Holden, Arthur, Deloukas, Panos, Pirmohamed, Munir
Publicado 2017

Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort

por Nicoletti, Paola, Carr, Daniel F., Barrett, Sarah, McEvoy, Laurence, Friedmann, Peter S., Shear, Neil H., Nelson, Matthew R., Chiriac, Anca M., Blanca-López, Natalia, Cornejo-García, José A., Gaeta, Francesco, Nakonechna, Alla, Torres, Maria J., Caruso, Cristiano, Valluzzi, Rocco L., Floratos, Aris, Shen, Yufeng, Pavlos, Rebecca K., Phillips, Elizabeth J., Demoly, Pascal, Romano, Antonino, Blanca, Miguel, Pirmohamed, Munir
Publicado 2021

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

por Floyd, James S., Bloch, Katarzyna M., Brody, Jennifer A., Maroteau, Cyrielle, Siddiqui, Moneeza K., Gregory, Richard, Carr, Daniel F., Molokhia, Mariam, Liu, Xiaoming, Bis, Joshua C., Ahmed, Ammar, Liu, Xuan, Hallberg, Pär, Yue, Qun-Ying, Magnusson, Patrik K. E., Brisson, Diane, Wiggins, Kerri L., Morrison, Alanna C., Khoury, Etienne, McKeigue, Paul, Stricker, Bruno H., Lapeyre-Mestre, Maryse, Heckbert, Susan R., Gallagher, Arlene M., Chinoy, Hector, Gibbs, Richard A., Bondon-Guitton, Emmanuelle, Tracy, Russell, Boerwinkle, Eric, Gaudet, Daniel, Conforti, Anita, van Staa, Tjeerd, Sitlani, Colleen M., Rice, Kenneth M., Maitland-van der Zee, Anke-Hilse, Wadelius, Mia, Morris, Andrew P., Pirmohamed, Munir, Palmer, Colin A. N., Psaty, Bruce M., Alfirevic, Ana
Publicado 2019

7th drug hypersensitivity meeting: part one

por Carr, Daniel F., Chung, Wen-Hung, Jenkiins, Rosalind E., Chaponda, Mas, Nwikue, Gospel, Cornejo Castro, Elena M., Antoine, Daniel J., Pirmohamed, Munir, Wuillemin, Natascha, Dina, Dolores, Eriksson, Klara K., Yerly, Daniel, Pavlos, Rebecca, Mckinnin, Elizabeth, Ostrov, David, Peters, Bjoern, Buus, Soren, Koelle, David, Chopra, Abha, Rive, Craig, Redwood, Alec, Restrepo, Susana, Bracey, Austin, Yuan, Jing, Gaudieri, Silvana, Carrington, Mary, Haas, David, Mallal, Simon, Phillips, Elizabeth, De Boer, Douwe, Menheere, Paul, Nieuwhof, Chris, Bons, Judith, Jonsson, Friederike, De Chaisemartin, Luc, Granger, Vanessa, Gillis, Caitlin, Gouel, Aurelie, Neukirch, Catherine, Dib, Fadia, Nicaise, Pascale Roland, Longrois, Dan, Tubach, Florence, Martin, Sylvie, Bruhns, Pierre, Chen, Kai-Lung, Liao, Shu-Ling, Sheen, Yi-Shuan, Cho, Yung-Tsu, Yang, Che-Wen, Liau, Jau-Yu, Chu, Chia-Yu, Aguiar, Rita, Lopes, Anabela, Fernandes, Natália, Viegas, Leonor, Pereira-Barbosa, M. A., Bünter, Antonia, Gupta, Nisha, Petkovic, Tatjana Pecaric, Wirth, Nicole, Pichler, Werner J., Hausmann, Oliver, Yazicioglu, Mehtap, Ozdemir, Pinar G., Ciplak, Gokce, Kaya, Ozkan, Cooke, Peter John, Mota, Inês, Gaspar, Ângela, Benito-Garcia, Filipe, Chambel, Marta, Morais-Almeida, Mário, Marques, Luis, Alcoceba, Eva, Lara, Silvia, Carneiro-Leão, Leonor, Botelho, Carmen, Dias-Castro, Eunice, Cernadas, Josefina R., Nicholls, Katherine, Lay, William, Smith, Olivia, Collins, Christine, Unglik, Gary, Spriggs, Kymble, Auyeung, Priscilla, McComish, Jeremy, Douglass, Jo A., Peter, Jonny G., Potter, Paul, Carolino, Fabrícia, De Castro, Eunice Dias, Moreira, Ana Sofia, Abreu, Carmo, Gomes, Eva, Cardoso, Bárbara Kong, Tomaz, Elza, Correia, Sara, Inácio, Filipe, Arnold, Annabelle, Bear, Natasha, Rueter, Kristina, Gong, Grace, O’Sullivan, Michael, Muthusamy, Saravanan, Noble, Valerie, Lucas, Michaela, Buterleviciute, Neringa, Rudzeviciene, Odilija, Abreu, Carmo, May, Sara, Pongdee, Thanai, Park, Miguel, Griguola, Linas, Vinikovas, Arturas, Kašinskaite, Simona, Kvedariene, Violeta, Aktas, Ayse, Rahman, Suheyla, Elbi, Huseyin, Ozyurt, Beyhan Cengiz, Cavkaytar, Ozlem, Karaatmaca, Betul, Cetinkaya, Pinar Gur, Esenboga, Saliha, Sahiner, Umit M., Sekerel, Bulent E., Soyer, Ozge, Zubrinich, Celia, Tong, Bianca, Patel, Mittal, Giles, Michelle, O’Hehir, Robyn, Puy, Robert, Amaral, Luís, Demir, Semra, Gelincik, Asli, Olgac, Muge, Caskun, Raif, Unal, Derya, Colakoglu, Bahauddin, Buyukozturk, Suna, Matute, Olga Vega, Bernad, Amalia, Gastaminza, Gabriel, Madamba, Roselle, Lacasa, Carlos, Goikoetxea, M. J., D’Amelio, Carmen, Rifón, Jose, Martínez, Nicolas, Ferrer, Marta, Ribeiro, Carmelita, Faria, Emília, Frutuoso, Cristina, Barros, Anabela, Lebre, Rosário, Pego, Alice, Bom, Ana Todo, Ensina, Luis Felipe, Aranda, Carolina, Nunes, Ines Camelo, Martins, Ana Maria, Solé, Dirceu, Bavbek, Sevim, Kendirlinan, Resat, Çerçi, Pamir, Tutluer, Seda, Soyyigit, Sadan, Sözener, Zeynep Çelebi, Aydin, Ömür, Gümüsburun, Reyhan, Almeida, Marta, Sai, Kimie, Imatoh, Takuya, Nakamura, Ryosuke, Fukazawa, Chisato, Hinomura, Yasushi, Saito, Yoshiro, Sousa-Pinto, Bernardo, Correia, Cláudia, Gomes, Lídia, Gil-Mata, Sara, Araújo, Luís, Delgado, Luís, Sai, Kimie, Okamoto-Uchida, Yoshimi, Kajinami, Koji, Matsunaga, Kayoko, Aihara, Michiko, Wang, Chuang-Wei, Su, Shih-Chi, Hung, Shuen-Iu, Ho, Hsin-Chun, Yang, Chih-Hsun, Paulmann, Maren, Dunant, Ariane, Mockenhaupt, Maja, Sekula, Peggy, Schumacher, Martin, Kardaun, Sylvia, Naldi, Luigi, Bellón, Teresa, Creamer, Daniel, Haddad, Cynthia, Sassolas, Bruno, Lebrun-Vignes, Bénédicte, Valeyrie-Allanore, Laurence, Roujeau, Jean-Claude, Paulmann, Maren, Kremmler, Carmen, Mockenhaupt, Maja, Dodiuk-Gad, Roni P., Olteanu, Cristina, Feinstein, Anthony, Hashimoto, Rena, Alhusayen, Raed, Whyte-Croasdaile, Sonia, Finkelstein, Yaron, Burnett, Marjorie, Sade, Shachar, Cartotto, Robert, Jeschke, Marc, Shear, Neil H., Takamura, Naoko, Yamane, Yumiko, Matsukura, Setsuko, Nakamura, Kazuko, Watanabe, Yuko, Yamaguchi, Yukie, Kambara, Takeshi, Ikezawa, Zenro, Aihara, Michiko, Hashimoto, Rena, Chew, Hall, Burnett, Marjorie, Jeschke, Marc, Knezevic, Brittany, Ionmhain, Una Nic, Barraclough, Allison, Anstey, Matthew, Usui, Toru, Meng, Xiaoli, Farrell, John, Whitaker, Paul, Watson, John, French, Neil, Park, Kevin, Naisbitt, Dean, Neves, Ana Castro, Cadinha, Susana, Moreira, Ana, Da Silva, J. P. Moreira, Drvar, Daniela Ledic, Gulin, Sandra Jerkovic, Hadzavdic, Suzana Ljubojevic, Ceovic, Romana, De Francisco, Ana Montoro, De Vicente Jiménez, Talía, Luque, Amelia García, David, Natalia Rosado, Galván, José Mª Mateos, Darlenski, Razvigor, Gulin, Dario, Sikic, Jozica, Habek, Jasna Cerkez, Galic, Edvard, Specht, Philip, Staab, Doris, Mayer, Beate, Roehmel, Jobst, Solovan, Caius, Chiriac, Anca, Djurinec, Paola, Kostovic, Kresimir, Bradamante, Mirna, Almeida, Jose Pedro, Caiado, Joana, Pedro, Elisa, Da Silva, Pedro Canas, Barbosa, Manuel Pereira, Bogas, Gador, Blanca-López, Natalia, Pérez-Alzate, Diana, Doña, Inmaculada, Agúndez, José Augusto, García-Martín, Elena, Cornejo-García, José Antonio, Mayorga, Cristobalina, Torres, María José, Canto, Maria Gabriela, Blanca, Miguel, Aksakal, Sengül, Sin, Aytül Zerrin, Koç, Zeynep Peker, Günsen, Fatma Düsünür, Ardeniz, Ömür, Gökmen, Emine Nihal Mete, Gülbahar, Okan, Kokuludag, Ali, Pérez-Sánchez, Natalia, Salas, María, Salas, Maria, Gomez, Francisca, Barrionuevo, Esther, Andreu, Inmaculada, Miranda, Miguel Ángel, Didžiokaite, Gabija, Gaidej, Olesia, Kašinskaite, Simona, Garcimartin, Maria Isabel, Somoza, Maria Luisa, Bojas, Gador, Cornejo-Garcia, Jose Antonio, Perez, Francisco Javier Ruano, Miranda, Miguel Angel, Jerschow, Elina, Pelletier, Teresa, Ren, Zhen, Hudes, Golda, Sanak, Marek, Morales, Esperanza, Schuster, Victor, Spivack, Simon D, Rosenstreich, David, Erzen, Renato, Silar, Mira, Bajrovic, Nissera, Rijavec, Matija, Zidarn, Mihaela, Korosec, Peter, Castro, Eunice, Al-Ahmad, Mona, Rodriguez, Tito, Azevedo, João Pedro, Tavares, Beatriz, Regateiro, Frederico, Todo-Bom, Ana, Miranda, Pablo Andrés, De La Cruz Hoyos, Bautista, Abuzeid, Waleed, Akbar, Nadeem, Gibber, Marc, Fried, Marvin, Han, Weiguo, Keskin, Taha, Tamayev, Robert, Spivack, Simon D., Rosenstreich, David, Jerschow, Elina, Boni, Elisa, Russello, Marina, Mauro, Marina, Neto, Marta Ferreira, Brosseron, Lise, Malheiro, Daniela, Barreira, Patrícia, Sprigg, Dustin, Trevenen, Michelle, Seet, Jason, Trubiano, Jason, Smith, William, Jeelall, Yogesh, Vale, Sandra, Loh, Richard, Mclean-Tooke, Andrew, Müller, Sabine, Amstutz, Ursula, Jörg, Lukas, Yawalkar, Nikhil, Krähenbühl, Stephan, Leblanc, Ana, Ribeiro, Laura, Vega, Arantza, Rivas, Raquel Gutierrez, Alonso, Ana, Beitia, Juan Maria, Mateo, Belén, Cárdenas, Remedios, Garcia-Dominguez, Juan Jesus, Pavlos, Rebecca, Strautins, Kaija, James, Ian, Mallal, Simon, Redwood, Alec, Aguiar, Rita, Lopes, Anabela, Neves, Ana, Do Céu Machado, Maria, Dalgiç, Ceyda Tunakan, Gökmen, Emine Nihal Mete, Bulut, Gökten, Ardeniz, Fatma Ömür, Gülbahar, Okan, Sin, Aytül Zerrin, Hsu, Shao-Hsuan, Yang, Che-Wen, Ye, Young-Min, Hur, Gyu-Young, Park, Hae-Sim, Kim, Seung-Hyun, Ali, Syed, Hollingsworth, Peter N., Mclean-Tooke, Andrew P. C., Chadly, Zohra, Fredj, Nadia Ben, Aouam, Karim, Romdhane, Haifa Ben, Boughattas, Naceur A., Chaabane, Amel, Salazar, Marina Lluncor, Pola, Beatriz, Fiandor, Ana, Ramírez, Elena, Ortega, Javier Domínguez, Quirce, Santiago, Cabañas, Rosario, Baynova, Krasimira, Labella, Marina, Prados, Manuel, Ramonaite, Agne, Bajoriuniene, Ieva, Sitkauskiene, Brigita, Sakalauskas, Raimundas, Kwon, Jae-Woo, Park, Shinyoung, Silva, Diana, Leão, Leonor Carneiro, Castro, Eunice, Garcimartin, Maria, De La Torre, Maria Vazquez, Pérez, Francisco Javier Ruano, Haroun, Elisa, Diez, Gabriela Canto, Ónodi-Nagy, Katinka, Kinyó, Ágnes, Kemény, Lajos, Bata-Csörgo, Zsuzsanna, Pita, Joana Sofia, Fernandes, Rosa Anita, Moura, Ana, Sousa, Nuno, Loureiro, Carlos, Pfützner, Wolfgang, Marrouche, Nadine, Grattan, Clive, Chen, Yu-En, Chen, Chun-Bing, Hsiao, Yu-Ping, Garcimartin, Maria Isabel, Ruano, Francisco Javier
Publicado 2016