A 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site Mutagenesis

por Naqvi, Tatheer, Warden, Andrew C., French, Nigel, Sugrue, Elena, Carr, Paul D., Jackson, Colin J., Scott, Colin
Publicado 2014

Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes

por Baier, Florian, Hong, Nansook, Yang, Gloria, Pabis, Anna, Miton, Charlotte M, Barrozo, Alexandre, Carr, Paul D, Kamerlin, Shina CL, Jackson, Colin J, Tokuriki, Nobuhiko
Publicado 2019

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

por Gsaller, Fabio, Hortschansky, Peter, Furukawa, Takanori, Carr, Paul D., Rash, Bharat, Capilla, Javier, Müller, Christoph, Bracher, Franz, Bowyer, Paul, Haas, Hubertus, Brakhage, Axel A., Bromley, Michael J.
Publicado 2016

Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

por Gsaller, Fabio, Hortschansky, Peter, Furukawa, Takanori, Carr, Paul D., Rash, Bharat, Capilla, Javier, Müller, Christoph, Bracher, Franz, Bowyer, Paul, Haas, Hubertus, Brakhage, Axel A., Bromley, Michael J.
Publicado 2016

The evolution of multiple active site configurations in a designed enzyme

por Hong, Nan-Sook, Petrović, Dušan, Lee, Richmond, Gryn’ova, Ganna, Purg, Miha, Saunders, Jake, Bauer, Paul, Carr, Paul D., Lin, Ching-Yeh, Mabbitt, Peter D., Zhang, William, Altamore, Timothy, Easton, Chris, Coote, Michelle L., Kamerlin, Shina C. L., Jackson, Colin J.
Publicado 2018