Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis

por Ma, Yue, Ratnasabapathy, Risheka, Izzi‐Engbeaya, Chioma, Nguyen‐Tu, Marie‐Sophie, Richardson, Errol, Hussain, Sufyan, De Backer, Ivan, Holton, Christopher, Norton, Mariana, Carrat, Gaelle, Schwappach, Blanche, Rutter, Guy A., Dhillo, Waljit S., Gardiner, James
Publicado 2018

In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist

por Jones, Ben, Burade, Vinod, Akalestou, Elina, Manchanda, Yusman, Ramchunder, Zenouska, Carrat, Gaëlle, Nguyen‐Tu, Marie‐Sophie, Marchetti, Piero, Piemonti, Lorenzo, Leclerc, Isabelle, Thennati, Rajamannar, Vilsboll, Tina, Thorens, Bernard, Tomas, Alejandra, Rutter, Guy A.
Publicado 2022

Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity

por Kleiner, Sandra, Gomez, Daniel, Megra, Bezawit, Na, Erqian, Bhavsar, Ramandeep, Cavino, Katie, Xin, Yurong, Rojas, Jose, Dominguez-Gutierrez, Giselle, Zambrowicz, Brian, Carrat, Gaelle, Chabosseau, Pauline, Hu, Ming, Murphy, Andrew J., Yancopoulos, George D., Rutter, Guy A., Gromada, Jesper
Publicado 2018

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion

por Hu, Ming, Cebola, Inês, Carrat, Gaelle, Jiang, Shuying, Nawaz, Sameena, Khamis, Amna, Canouil, Mickaël, Froguel, Philippe, Schulte, Anke, Solimena, Michele, Ibberson, Mark, Marchetti, Piero, Cardenas-Diaz, Fabian L., Gadue, Paul J., Hastoy, Benoit, Alemeida-Souza, Leonardo, McMahon, Harvey, Rutter, Guy A.
Publicado 2021

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion

por Hu, Ming, Cebola, Inês, Carrat, Gaelle, Jiang, Shuying, Nawaz, Sameena, Khamis, Amna, Canouil, Mickaël, Froguel, Philippe, Schulte, Anke, Solimena, Michele, Ibberson, Mark, Marchetti, Piero, Cardenas-Diaz, Fabian L., Gadue, Paul J., Hastoy, Benoit, Almeida-Souza, Leonardo, McMahon, Harvey, Rutter, Guy A.
Publicado 2021

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice

por Carrat, Gaelle R., Hu, Ming, Nguyen-Tu, Marie-Sophie, Chabosseau, Pauline, Gaulton, Kyle J., van de Bunt, Martijn, Siddiq, Afshan, Falchi, Mario, Thurner, Matthias, Canouil, Mickaël, Pattou, Francois, Leclerc, Isabelle, Pullen, Timothy J., Cane, Matthew C., Prabhala, Priyanka, Greenwald, William, Schulte, Anke, Marchetti, Piero, Ibberson, Mark, MacDonald, Patrick E., Manning Fox, Jocelyn E., Gloyn, Anna L., Froguel, Philippe, Solimena, Michele, McCarthy, Mark I., Rutter, Guy A.
Publicado 2017

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

por Carrat, Gaelle R., Haythorne, Elizabeth, Tomas, Alejandra, Haataja, Leena, Müller, Andreas, Arvan, Peter, Piunti, Alexandra, Cheng, Kaiying, Huang, Mutian, Pullen, Timothy J., Georgiadou, Eleni, Stylianides, Theodoros, Amirruddin, Nur Shabrina, Salem, Victoria, Distaso, Walter, Cakebread, Andrew, Heesom, Kate J., Lewis, Philip A., Hodson, David J., Briant, Linford J., Fung, Annie C.H., Sessions, Richard B., Alpy, Fabien, Kong, Alice P.S., Benke, Peter I., Torta, Federico, Teo, Adrian Kee Keong, Leclerc, Isabelle, Solimena, Michele, Wigley, Dale B., Rutter, Guy A.
Publicado 2020

The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans

por Izzi‐Engbeaya, Chioma, Comninos, Alexander N., Clarke, Sophie A., Jomard, Anne, Yang, Lisa, Jones, Sophie, Abbara, Ali, Narayanaswamy, Shakunthala, Eng, Pei Chia, Papadopoulou, Deborah, Prague, Julia K., Bech, Paul, Godsland, Ian F., Bassett, Paul, Sands, Caroline, Camuzeaux, Stephane, Gomez‐Romero, Maria, Pearce, Jake T. M., Lewis, Matthew R., Holmes, Elaine, Nicholson, Jeremy K., Tan, Tricia, Ratnasabapathy, Risheka, Hu, Ming, Carrat, Gaelle, Piemonti, Lorenzo, Bugliani, Marco, Marchetti, Piero, Johnson, Paul R., Hughes, Stephen J., James Shapiro, A. M., Rutter, Guy A., Dhillo, Waljit S.
Publicado 2018