Altering Compositional Properties of Viral Genomes to Design Live-Attenuated Vaccines

por Pereira-Gómez, Marianoel, Carrau, Lucía, Fajardo, Álvaro, Moreno, Pilar, Moratorio, Gonzalo
Publicado 2021

First Genome Sequence of a Canine Distemper Virus Strain from South America

por Sarute, Nicolás, Delgado, María V., Carrau, Lucía, Benech, Alejandro, Francia, Lourdes, Pérez, Ruben, Panzera, Yanina
Publicado 2014

Complete Genome Sequence of a Novel Recombinant Citrus Tristeza Virus, a Resistance-Breaking Isolate from Uruguay

por Benítez-Galeano, María José, Vallet, Thomas, Carrau, Lucía, Hernández-Rodríguez, Lester, Bertalmío, Ana, Rivas, Fernando, Rubio, Leticia, Maeso, Diego, Vignuzzi, Marco, Moratorio, Gonzalo, Colina, Rodney
Publicado 2018

Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are Attenuated In Vivo and Have Compromised Transmissibility

por Carrau, Lucía, Rezelj, Veronica V., Noval, María G., Levi, Laura I., Megrian, Daniela, Blanc, Herve, Weger-Lucarelli, James, Moratorio, Gonzalo, Stapleford, Kenneth A., Vignuzzi, Marco
Publicado 2019

Host nutritional status affects alphavirus virulence, transmission, and evolution

por Weger-Lucarelli, James, Carrau, Lucia, Levi, Laura I., Rezelj, Veronica, Vallet, Thomas, Blanc, Hervé, Boussier, Jérémy, Megrian, Daniela, Coutermarsh-Ott, Sheryl, LeRoith, Tanya, Vignuzzi, Marco
Publicado 2019

Attenuation of RNA viruses by redirecting their evolution in sequence space

por Moratorio, Gonzalo, Henningsson, Rasmus, Barbezange, Cyril, Carrau, Lucia, Bordería, Antonio V., Blanc, Hervé, Beaucourt, Stephanie, Poirier, Enzo Z., Vallet, Thomas, Boussier, Jeremy, Mounce, Bryan C., Fontes, Magnus, Vignuzzi, Marco
Publicado 2017

Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes

por Levi, Laura I., Rezelj, Veronica V., Henrion-Lacritick, Annabelle, Erazo, Diana, Boussier, J, Vallet, Thomas, Bernhauerová, Veronika, Suzuki, Yasutsugu, Carrau, Lucia, Weger-Lucarelli, James, Saleh, Maria-Carla, Vignuzzi, Marco
Publicado 2021

Phylogenetic and Genome-Wide Deep-Sequencing Analyses of Canine Parvovirus Reveal Co-Infection with Field Variants and Emergence of a Recent Recombinant Strain

por Pérez, Ruben, Calleros, Lucía, Marandino, Ana, Sarute, Nicolás, Iraola, Gregorio, Grecco, Sofia, Blanc, Hervé, Vignuzzi, Marco, Isakov, Ofer, Shomron, Noam, Carrau, Lucía, Hernández, Martín, Francia, Lourdes, Sosa, Katia, Tomás, Gonzalo, Panzera, Yanina
Publicado 2014

Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19

por Laurent, Paôline, Yang, Chao, Rendeiro, André F., Nilsson-Payant, Benjamin E., Carrau, Lucia, Chandar, Vasuretha, Bram, Yaron, tenOever, Benjamin R., Elemento, Olivier, Ivashkiv, Lionel B., Schwartz, Robert E., Barrat, Franck J.
Publicado 2022

Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection

por Adrover, Jose M., Carrau, Lucia, Daßler-Plenker, Juliane, Bram, Yaron, Chandar, Vasuretha, Houghton, Sean, Redmond, David, Merrill, Joseph R., Shevik, Margaret, tenOever, Benjamin R., Lyons, Scott K., Schwartz, Robert E., Egeblad, Mikala
Publicado 2022

A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection

por Tang, Xuming, Xue, Dongxiang, Zhang, Tuo, Nilsson-Payant, Benjamin E., Carrau, Lucia, Duan, Xiaohua, Gordillo, Miriam, Tan, Adrian Y., Qiu, Yunping, Xiang, Jenny, Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Publicado 2023

Mouse genome rewriting and tailoring of three important disease loci

por Zhang, Weimin, Golynker, Ilona, Brosh, Ran, Fajardo, Alvaro, Zhu, Yinan, Wudzinska, Aleksandra M., Ordoñez, Raquel, Ribeiro-dos-Santos, André M., Carrau, Lucia, Damani-Yokota, Payal, Yeung, Stephen T., Khairallah, Camille, Vela Gartner, Antonio, Chalhoub, Noor, Huang, Emily, Ashe, Hannah J., Khanna, Kamal M., Maurano, Matthew T., Kim, Sang Yong, tenOever, Benjamin R., Boeke, Jef D.
Publicado 2023

SARS-CoV-2 Infects Syncytiotrophoblast and Activates Inflammatory Responses in the Placenta

por Argueta, Lissenya B., Lacko, Lauretta A., Bram, Yaron, Tada, Takuya, Carrau, Lucia, Zhang, Tuo, Uhl, Skyler, Lubor, Brienne C., Chandar, Vasuretha, Gil, Cristianel, Zhang, Wei, Dodson, Brittany, Bastiaans, Jeroen, Prabhu, Malavika, Salvatore, Christine M., Yang, Yawei J., Baergen, Rebecca N., tenOever, Benjamin R., Landau, Nathaniel R., Chen, Shuibing, Schwartz, Robert E., Stuhlmann, Heidi
Publicado 2021

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito

por Cereghino, Chelsea, Roesch, Ferdinand, Carrau, Lucía, Hardy, Alexandra, Ribeiro-Filho, Helder V., Henrion-Lacritick, Annabelle, Koh, Cassandra, Marano, Jeffrey M., Bates, Tyler A., Rai, Pallavi, Chuong, Christina, Akter, Shamima, Vallet, Thomas, Blanc, Hervé, Elliott, Truitt J., Brown, Anne M., Michalak, Pawel, LeRoith, Tanya, Bloom, Jesse D., Marques, Rafael Elias, Saleh, Maria-Carla, Vignuzzi, Marco, Weger-Lucarelli, James
Publicado 2023

Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts

por Rezelj, Veronica V., Carrau, Lucía, Merwaiss, Fernando, Levi, Laura I., Erazo, Diana, Tran, Quang Dinh, Henrion-Lacritick, Annabelle, Gausson, Valérie, Suzuki, Yasutsugu, Shengjuler, Djoshkun, Meyer, Bjoern, Vallet, Thomas, Weger-Lucarelli, James, Bernhauerová, Veronika, Titievsky, Avi, Sharov, Vadim, Pietropaoli, Stefano, Diaz-Salinas, Marco A., Legros, Vincent, Pardigon, Nathalie, Barba-Spaeth, Giovanna, Brodsky, Leonid, Saleh, Maria-Carla, Vignuzzi, Marco
Publicado 2021

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

por Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Publicado 2021

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

por Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Publicado 2021

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

por Samelson, Avi J., Tran, Quang Dinh, Robinot, Rémy, Carrau, Lucia, Rezelj, Veronica V., Mac Kain, Alice, Chen, Merissa, Ramadoss, Gokul N., Guo, Xiaoyan, Lim, Shion A., Lui, Irene, Nunez, James, Rockwood, Sarah J., Wang, Jianhui, Liu, Na, Carlson-Stevermer, Jared, Oki, Jennifer, Maures, Travis, Holden, Kevin, Weissman, Jonathan S., Wells, James A., Conklin, Bruce R., TenOever, Benjamin R., Chakrabarti, Lisa A., Vignuzzi, Marco, Tian, Ruilin, Kampmann, Martin
Publicado 2021

Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy

por Argueta, Lissenya B., Lacko, Lauretta A., Bram, Yaron, Tada, Takuya, Carrau, Lucia, Rendeiro, André Figueiredo, Zhang, Tuo, Uhl, Skyler, Lubor, Brienne C., Chandar, Vasuretha, Gil, Cristianel, Zhang, Wei, Dodson, Brittany J., Bastiaans, Jeroen, Prabhu, Malavika, Houghton, Sean, Redmond, David, Salvatore, Christine M., Yang, Yawei J., Elemento, Olivier, Baergen, Rebecca N., tenOever, Benjamin R., Landau, Nathaniel R., Chen, Shuibing, Schwartz, Robert E., Stuhlmann, Heidi
Publicado 2022

Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2

por Reiterer, Moritz, Rajan, Mangala, Gómez-Banoy, Nicolás, Lau, Jennifer D., Gomez-Escobar, Luis G., Ma, Lunkun, Gilani, Ankit, Alvarez-Mulett, Sergio, Sholle, Evan T., Chandar, Vasuretha, Bram, Yaron, Hoffman, Katherine, Bhardwaj, Priya, Piloco, Phoebe, Rubio-Navarro, Alfonso, Uhl, Skyler, Carrau, Lucia, Houhgton, Sean, Redmond, David, Shukla, Alpana P., Goyal, Parag, Brown, Kristy A., tenOever, Benjamin R., Alonso, Laura C., Schwartz, Robert E., Schenck, Edward J., Safford, Monika M., Lo, James C.
Publicado 2021