Purified human BRCA2 stimulates RAD51-mediated recombination

por Jensen, Ryan B., Carreira, Aura, Kowalczykowski, Stephen C.
Publicado 2010

Missense Variants of Uncertain Significance: A Powerful Genetic Tool for Function Discovery with Clinical Implications

por Sessa, Gaetana, Ehlén, Åsa, von Nicolai, Catharina, Carreira, Aura
Publicado 2021

A second DNA binding site in human BRCA2 promotes homologous recombination

por von Nicolai, Catharina, Ehlén, Åsa, Martin, Charlotte, Zhang, Xiaodong, Carreira, Aura
Publicado 2016

Intrinsic Disorder and Phosphorylation in BRCA2 Facilitate Tight Regulation of Multiple Conserved Binding Events

por Julien, Manon, Ghouil, Rania, Petitalot, Ambre, Caputo, Sandrine M., Carreira, Aura, Zinn-Justin, Sophie
Publicado 2021

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

por Ehlén, Åsa, Martin, Charlotte, Miron, Simona, Julien, Manon, Theillet, François-Xavier, Ropars, Virginie, Sessa, Gaetana, Beaurepere, Romane, Boucherit, Virginie, Duchambon, Patricia, El Marjou, Ahmed, Zinn-Justin, Sophie, Carreira, Aura
Publicado 2020

Replication gap suppression depends on the double-strand DNA binding activity of BRCA2

por Vugic, Domagoj, Dumoulin, Isaac, Martin, Charlotte, Minello, Anna, Alvaro-Aranda, Lucia, Gomez-Escudero, Jesus, Chaaban, Rady, Lebdy, Rana, von Nicolai, Catharina, Boucherit, Virginie, Ribeyre, Cyril, Constantinou, Angelos, Carreira, Aura
Publicado 2023

Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant

por Mishra, Arun Prakash, Hartford, Suzanne, Chittela, Rajani Kant, Sahu, Sounak, Kharat, Suhas S., Alvaro-Aranda, Lucia, Contreras-Perez, Aida, Sullivan, Teresa, Martin, Betty K., Albaugh, Mary, Southon, Eileen, Burkett, Sandra, Karim, Baktiar, Carreira, Aura, Tessarollo, Lino, Sharan, Shyam K.
Publicado 2023

Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer

por Caputo, Sandrine M., Léone, Mélanie, Damiola, Francesca, Ehlen, Asa, Carreira, Aura, Gaidrat, Pascaline, Martins, Alexandra, Brandão, Rita D., Peixoto, Ana, Vega, Ana, Houdayer, Claude, Delnatte, Capucine, Bronner, Myriam, Muller, Danièle, Castera, Laurent, Guillaud-Bataille, Marine, Søkilde, Inge, Uhrhammer, Nancy, Demontety, Sophie, Tubeuf, Hélène, Castelain, Gaïa, Jensen, Uffe Birk, Petitalot, Ambre, Krieger, Sophie, Lefol, Cédrick, Moncoutier, Virginie, Boutry-Kryza, Nadia, Nielsen, Henriette Roed, Sinilnikova, Olga, Stoppa-Lyonnet, Dominique, Spurdle, Amanda B., Teixeira, Manuel R., Coulet, Florence, Thomassen, Mads, Rouleau, Etienne
Publicado 2018