Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation

por Reddy, P. Anantha, Jones, Sean T., Lewin, Anita H., Carroll, F. Ivy
Publicado 2012

A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336

por Carroll, F. Ivy, Kosten, Thomas R., Buda, Jeffrey J., Wang, Laurene, Walters, Bradford B.
Publicado 2018

Interactions between 2′-fluoro-(carbamoyl­pyridinyl)deschloroepibatidine analogues and acetylcholine-binding protein inform on potent antagonist activity against nicotinic receptor...

por Bueno, Renata V., Davis, Samuel, Dawson, Alice, Ondachi, Pauline W., Carroll, F. Ivy, Hunter, William N.
Publicado 2022

Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity

por Munro, Thomas A, Berry, Loren M, Van’t Veer, Ashlee, Béguin, Cécile, Carroll, F Ivy, Zhao, Zhiyang, Carlezon, William A, Cohen, Bruce M
Publicado 2012

Behavioral Pharmacology of Novel Kappa Opioid Receptor Antagonists in Rats

por Page, Sarah, Mavrikaki, Maria M, Lintz, Tania, Puttick, Daniel, Roberts, Edward, Rosen, Hugh, Carroll, F Ivy, Carlezon, William A, Chartoff, Elena H
Publicado 2019

Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2′-Fluoro-3′-(substituted pyridinyl)-7-deschloroepibatidine Analogues

por Ondachi, Pauline W., Castro, Ana H., Bartkowiak, Jakub M., Luetje, Charles W., Damaj, M. Imad, Mascarella, S. Wayne, Navarro, Hernán A., Carroll, F. Ivy
Publicado 2014

Design, Synthesis, and Biological Evaluation of (3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoqu...

por Kormos, Chad M., Gichinga, Moses G., Maitra, Rangan, Runyon, Scott P., Thomas, James B., Brieaddy, Lawrence E., Mascarella, S. Wayne, Navarro, Hernán A., Carroll, F. Ivy
Publicado 2014

Simple Radiometric Method for Accurately Quantitating Epitope Densities of Hapten–Protein Conjugates with Sulfhydryl Linkages

por Peterson, Eric C., Hambuchen, Michael D., Tawney, Rachel L., Gunnell, Melinda G., Cowell, James L., Lay, Jackson O., Blough, Bruce E., Carroll, F. Ivy, Owens, S. Michael
Publicado 2014

Serotonin transporter inhibition and 5-HT(2C) receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice

por Stewart, Adele, Davis, Gwynne L., Gresch, Paul J., Katamish, Rania M., Peart, Rodeania, Rabil, Maximilian J., Gowrishankar, Raajaram, Carroll, F. Ivy, Hahn, Maureen K., Blakely, Randy D.
Publicado 2018

Effect of the 3- and 4-Methyl Groups on the Opioid Receptor Properties of N-Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines

por Kormos, Chad M., Cueva, Juan Pablo, Gichinga, Moses G., Runyon, Scott P., Thomas, James B., Brieaddy, Lawrence E., Mascarella, S. Wayne, Gilmour, Brian P., Navarro, Hernán A., Carroll, F. Ivy
Publicado 2014

Selective κ Opioid Antagonists nor-BNI, GNTI and JDTic Have Low Affinities for Non-Opioid Receptors and Transporters

por Munro, Thomas A., Huang, Xi-Ping, Inglese, Carmela, Perrone, Maria Grazia, Van't Veer, Ashlee, Carroll, F. Ivy, Béguin, Cécile, Carlezon, William A., Colabufo, Nicola A., Cohen, Bruce M., Roth, Bryan L.
Publicado 2013

Nanobody-enabled monitoring of kappa opioid receptor states

por Che, Tao, English, Justin, Krumm, Brian E., Kim, Kuglae, Pardon, Els, Olsen, Reid H. J., Wang, Sheng, Zhang, Shicheng, Diberto, Jeffrey F., Sciaky, Noah, Carroll, F. Ivy, Steyaert, Jan, Wacker, Daniel, Roth, Bryan L.
Publicado 2020

Molecular mechanism of biased signaling at the kappa opioid receptor

por El Daibani, Amal, Paggi, Joseph M., Kim, Kuglae, Laloudakis, Yianni D., Popov, Petr, Bernhard, Sarah M., Krumm, Brian E., Olsen, Reid H. J., Diberto, Jeffrey, Carroll, F. Ivy, Katritch, Vsevolod, Wünsch, Bernhard, Dror, Ron O., Che, Tao
Publicado 2023

Blood levels of T-Cell Receptor Excision Circles (TRECs) provide an index of exposure to traumatic stress in mice and humans

por McCullough, Kenneth M., Katrinli, Seyma, Hartmann, Jakob, Lori, Adriana, Klengel, Claudia, Missig, Galen, Klengel, Torsten, Langford, Nicole A., Newman, Emily L., Anderson, Kasey J., Smith, Alicia K., Carroll, F. Ivy, Ressler, Kerry J., Carlezon, William A.
Publicado 2022

Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test

por Laman-Maharg, Abigail, Williams, Alexia V., Zufelt, Mikaela D., Minie, Vanessa A., Ramos-Maciel, Stephanie, Hao, Rebecca, Ordoñes Sanchez, Evelyn, Copeland, Tiffany, Silverman, Jill L., Leigh, Angelina, Snyder, Rodney, Carroll, F. Ivy, Fennell, Timothy R., Trainor, Brian C.
Publicado 2018

Structure of the human kappa opioid receptor in complex with JDTic

por Wu, Huixian, Wacker, Daniel, Katritch, Vsevolod, Mileni, Mauro, Han, Gye Won, Vardy, Eyal, Liu, Wei, Thompson, Aaron A., Huang, Xi-Ping, Carroll, F. Ivy, Mascarella, S. Wayne, Westkaemper, Richard B., Mosier, Philip D., Roth, Bryan L., Cherezov, Vadim, Stevens, Raymond C.
Publicado 2012