Should I stay or should I go? Spatio-temporal control of cellular anchorage by hematopoietic factors orchestrates tumor metastatic cascade

por Marabitti, Veronica, Caruana, Ignazio, Nazio, Francesca
Publicado 2023

T lymphocytes against solid malignancies: winning ways to defeat tumours

por Caruana, Ignazio, Simula, Luca, Locatelli, Franco, Campello, Silvia
Publicado 2018

Manipulating the Metabolism to Improve the Efficacy of CAR T-Cell Immunotherapy

por Pellegrino, Marsha, Del Bufalo, Francesca, De Angelis, Biagio, Quintarelli, Concetta, Caruana, Ignazio, de Billy, Emmanuel
Publicado 2020

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T-lymphocytes

por Caruana, Ignazio, Savoldo, Barbara, Hoyos, Valentina, Weber, Gerrit, Liu, Hao, Kim, Eugene S., Ittmann, Michael M., Marchetti, Dario, Dotti, Gianpietro
Publicado 2015

Chimeric Antigen Receptor T-Cell Therapy in Paediatric B-Cell Precursor Acute Lymphoblastic Leukaemia: Curative Treatment Option or Bridge to Transplant?

por Buechner, Jochen, Caruana, Ignazio, Künkele, Annette, Rives, Susana, Vettenranta, Kim, Bader, Peter, Peters, Christina, Baruchel, André, Calkoen, Friso G.
Publicado 2022

Pediatric Tumors-Mediated Inhibitory Effect on NK Cells: The Case of Neuroblastoma and Wilms’ Tumors

por Pelosi, Andrea, Fiore, Piera Filomena, Di Matteo, Sabina, Veneziani, Irene, Caruana, Ignazio, Ebert, Stefan, Munari, Enrico, Moretta, Lorenzo, Maggi, Enrico, Azzarone, Bruno
Publicado 2021

Wilms’ Tumor Primary Cells Display Potent Immunoregulatory Properties on NK Cells and Macrophages

por Fiore, Piera Filomena, Vacca, Paola, Tumino, Nicola, Besi, Francesca, Pelosi, Andrea, Munari, Enrico, Marconi, Marcella, Caruana, Ignazio, Pistoia, Vito, Moretta, Lorenzo, Azzarone, Bruno
Publicado 2021

Cytotoxic effects and tolerability of gemcitabine and axitinib in a xenograft model for c-myc amplified medulloblastoma

por Schwinn, Stefanie, Mokhtari, Zeinab, Thusek, Sina, Schneider, Theresa, Sirén, Anna-Leena, Tiemeyer, Nicola, Caruana, Ignazio, Miele, Evelina, Schlegel, Paul G., Beilhack, Andreas, Wölfl, Matthias
Publicado 2021

Identification of New Soluble Factors Correlated With the Development of Graft Failure After Haploidentical Hematopoietic Stem Cell Transplantation

por Weber, Gerrit, Strocchio, Luisa, Del Bufalo, Francesca, Algeri, Mattia, Pagliara, Daria, Arnone, Claudia Manuela, De Angelis, Biagio, Quintarelli, Concetta, Locatelli, Franco, Merli, Pietro, Caruana, Ignazio
Publicado 2021

IMMU-07. Interim analysis of the HIT-HGG Rez Immunvac study - Dendritic cell vaccination with partial T(reg) depletion and double checkpoint blockade in children with relapsed high...

por Eyrich, Matthias, Krauss, Jürgen, Ghaffari, Maryam, Caruana, Ignazio, Rachor, Johannes, Monoranu, Camelia-Maria, Bison, Brigitte, Rückriegel, Stefan, Wölfl, Matthias, Miller, Elisabeth, Schlegel, Paul-Gerhardt, Kramm, Christof
Publicado 2022

Reversible induction of mitophagy by an optogenetic bimodular system

por D’Acunzo, Pasquale, Strappazzon, Flavie, Caruana, Ignazio, Meneghetti, Giacomo, Di Rita, Anthea, Simula, Luca, Weber, Gerrit, Del Bufalo, Francesca, Dalla Valle, Luisa, Campello, Silvia, Locatelli, Franco, Cecconi, Francesco
Publicado 2019

JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction

por Simula, Luca, Corrado, Mauro, Accordi, Benedetta, Di Rita, Anthea, Nazio, Francesca, Antonucci, Ylenia, Di Daniele, Arianna, Caicci, Federico, Caruana, Ignazio, Soriano, Maria Eugenia, Pigazzi, Martina, Locatelli, Franco, Cecconi, Francesco, Campello, Silvia
Publicado 2020

Preservation of Antigen-Specific Functions of αβ T Cells and B Cells Removed from Hematopoietic Stem Cell Transplants Suggests Their Use As an Alternative Cell Source for Advanced...

por Li Pira, Giuseppina, Di Cecca, Stefano, Biagini, Simone, Girolami, Elia, Cicchetti, Elisabetta, Bertaina, Valentina, Quintarelli, Concetta, Caruana, Ignazio, Lucarelli, Barbarella, Merli, Pietro, Pagliara, Daria, Brescia, Letizia Pomponia, Bertaina, Alice, Montanari, Mauro, Locatelli, Franco
Publicado 2017

Universal Ready-to-Use Immunotherapeutic Approach for the Treatment of Cancer: Expanded and Activated Polyclonal γδ Memory T Cells

por Polito, Vinicia A., Cristantielli, Rosaria, Weber, Gerrit, Del Bufalo, Francesca, Belardinilli, Tamascia, Arnone, Claudia M., Petretto, Andrea, Antonucci, Laura, Giorda, Ezio, Tumino, Nicola, Pitisci, Angela, De Angelis, Biagio, Quintarelli, Concetta, Locatelli, Franco, Caruana, Ignazio
Publicado 2019

Identification of neuroblastoma cell lines with uncommon TAZ(+)/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells

por Canzonetta, Claudia, Pelosi, Andrea, Di Matteo, Sabina, Veneziani, Irene, Tumino, Nicola, Vacca, Paola, Munari, Enrico, Pezzullo, Marco, Theuer, Charles, De Vito, Rita, Pistoia, Vito, Tomao, Luigi, Locatelli, Franco, Moretta, Lorenzo, Caruana, Ignazio, Azzarone, Bruno
Publicado 2021

Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma

por Tumino, Nicola, Weber, Gerrit, Besi, Francesca, Del Bufalo, Francesca, Bertaina, Valentina, Paci, Paola, Quatrini, Linda, Antonucci, Laura, Sinibaldi, Matilde, Quintarelli, Concetta, Maggi, Enrico, De Angelis, Biagio, Locatelli, Franco, Moretta, Lorenzo, Vacca, Paola, Caruana, Ignazio
Publicado 2021

MODL-23. DNA METHYLATION AND COPY NUMBER VARIATION PROFILE FOR CHARACTERIZATION OF PEDIATRIC BRAIN TUMOR PRIMARY CELL LINES

por Pedace, Lucia, Vinci, Maria, Pizzi, Simone, Pericoli, Giulia, Catanzaro, Giuseppina, Abballe, Luana, Del Bufalo, Francesca, Caruana, Ignazio, Camassei, Francesca Diomedi, Rossi, Sabrina, Giangaspero, Felice, Ferretti, Elisabetta, Ciolfi, Andrea, Tartaglia, Marco, Locatelli, Franco, Mastronuzzi, Angela, Miele, Evelina
Publicado 2020

GD2 redirected CAR T and activated NK-cell-mediated secretion of IFNγ overcomes MYCN-dependent IDO1 inhibition, contributing to neuroblastoma cell immune escape

por Caforio, Matteo, Sorino, Cristina, Caruana, Ignazio, Weber, Gerrit, Camera, Antonio, Cifaldi, Loredana, De Angelis, Biagio, Del Bufalo, Francesca, Vitale, Alessia, Goffredo, Bianca Maria, De Vito, Rita, Fruci, Doriana, Quintarelli, Concetta, Fanciulli, Maurizio, Locatelli, Franco, Folgiero, Valentina
Publicado 2021

Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma

por Quintarelli, Concetta, Orlando, Domenico, Boffa, Iolanda, Guercio, Marika, Polito, Vinicia Assunta, Petretto, Andrea, Lavarello, Chiara, Sinibaldi, Matilde, Weber, Gerrit, Del Bufalo, Francesca, Giorda, Ezio, Scarsella, Marco, Petrini, Stefania, Pagliara, Daria, Locatelli, Franco, De Angelis, Biagio, Caruana, Ignazio
Publicado 2018

Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation

por Merli, Pietro, Caruana, Ignazio, De Vito, Rita, Strocchio, Luisa, Weber, Gerrit, Bufalo, Francesca Del, Buatois, Vanessa, Montanari, Paolo, Cefalo, Maria Giuseppina, Pitisci, Angela, Algeri, Mattia, Galaverna, Federica, Quintarelli, Concetta, Cirillo, Valentina, Pagliara, Daria, Ferlin, Walter, Ballabio, Maria, De Min, Cristina, Locatelli, Franco
Publicado 2019