Distinct Stress Response and Altered Striatal Transcriptome in Alpha-Synuclein Overexpressing Mice

por Wassouf, Zinah, Hentrich, Thomas, Casadei, Nicolas, Jaumann, Mirko, Knipper, Marlies, Riess, Olaf, Schulze-Hentrich, Julia M.
Publicado 2019

Miro1 R272Q disrupts mitochondrial calcium handling and neurotransmitter uptake in dopaminergic neurons

por Schwarz, Lisa, Sharma, Karan, Dodi, Lorenzo D., Rieder, Lara-Sophie, Fallier-Becker, Petra, Casadei, Nicolas, Fitzgerald, Julia C.
Publicado 2022

SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells

por Singh, Yogesh, Trautwein, Christoph, Fendel, Rolf, Krickeberg, Naomi, Berezhnoy, Georgy, Bissinger, Rosi, Ossowski, Stephan, Salker, Madhuri S., Casadei, Nicolas, Riess, Olaf
Publicado 2021

Imaging of α-Synuclein Aggregates in a Rat Model of Parkinson’s Disease Using Raman Microspectroscopy

por Sevgi, Fide, Brauchle, Eva M., Carvajal Berrio, Daniel A., Schenke-Layland, Katja, Casadei, Nicolas, Salker, Madhuri S., Riess, Olaf, Singh, Yogesh
Publicado 2021

Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression

por Wassouf, Zinah, Hentrich, Thomas, Samer, Sebastian, Rotermund, Carola, Kahle, Philipp J., Ehrlich, Ingrid, Riess, Olaf, Casadei, Nicolas, Schulze-Hentrich, Julia M.
Publicado 2018

Endogenous but not sensory-driven activity controls migration, morphogenesis and survival of adult-born juxtaglomerular neurons in the mouse olfactory bulb

por Li, Kaizhen, Figarella, Katherine, Su, Xin, Kovalchuk, Yury, Gorzolka, Jessika, Neher, Jonas J., Mojtahedi, Nima, Casadei, Nicolas, Hedrich, Ulrike B. S., Garaschuk, Olga
Publicado 2023

rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

por Oliveras-Salvá, Marusela, Van der Perren, Anke, Casadei, Nicolas, Stroobants, Stijn, Nuber, Silke, D’Hooge, Rudi, Van den Haute, Chris, Baekelandt, Veerle
Publicado 2013

Dynamic footprints of α-synucleinopathic mice recorded by CatWalk gait analysis

por Timotius, Ivanna K., Canneva, Fabio, Minakaki, Georgia, Pasluosta, Cristian, Moceri, Sandra, Casadei, Nicolas, Riess, Olaf, Winkler, Jürgen, Klucken, Jochen, von Hörsten, Stephan, Eskofier, Bjoern
Publicado 2018

Enriched Environmental Conditions Modify the Gut Microbiome Composition and Fecal Markers of Inflammation in Parkinson’s Disease

por Singh, Yogesh, El-Hadidi, Mohamed, Admard, Jakob, Wassouf, Zinah, Schulze-Hentrich, Julia M., Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Huson, Daniel, Riess, Olaf, Casadei, Nicolas
Publicado 2019

Unraveling Molecular Mechanisms of THAP1 Missense Mutations in DYT6 Dystonia

por Cheng, Fubo, Walter, Michael, Wassouf, Zinah, Hentrich, Thomas, Casadei, Nicolas, Schulze-Hentrich, Julia, Barbuti, Peter, Krueger, Rejko, Riess, Olaf, Grundmann-Hauser, Kathrin, Ott, Thomas
Publicado 2020

Human Leucocyte Antigen G and Murine Qa-2 Are Critical for Myeloid Derived Suppressor Cell Expansion and Activation and for Successful Pregnancy Outcome

por Dietz, Stefanie, Schwarz, Julian, Velic, Ana, González-Menéndez, Irene, Quintanilla-Martinez, Leticia, Casadei, Nicolas, Marmé, Alexander, Poets, Christian F., Gille, Christian, Köstlin-Gille, Natascha
Publicado 2022

Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson’s study

por Pachchek, Sinthuja, Landoulsi, Zied, Pavelka, Lukas, Schulte, Claudia, Buena-Atienza, Elena, Gross, Caspar, Hauser, Ann-Kathrin, Reddy Bobbili, Dheeraj, Casadei, Nicolas, May, Patrick, Krüger, Rejko
Publicado 2023

Silhouette-Length-Scaled Gait Parameters for Motor Functional Analysis in Mice and Rats

por Timotius, Ivanna K., Moceri, Sandra, Plank, Anne-Christine, Habermeyer, Johanna, Canneva, Fabio, Winkler, Jürgen, Klucken, Jochen, Casadei, Nicolas, Riess, Olaf, Eskofier, Bjoern, von Hörsten, Stephan
Publicado 2019

Genome sequencing identifies complex structural MLH1 variant in unsolved Lynch syndrome

por Witt, Dennis, Faust, Ulrike, Strobl‐Wildemann, Gertrud, Sturm, Marc, Buchert, Rebecca, Zuleger, Theresia, Admard, Jakob, Casadei, Nicolas, Ossowski, Stephan, Haack, Tobias B., Rieß, Olaf, Schroeder, Christopher
Publicado 2023

Calpains as novel players in the molecular pathogenesis of spinocerebellar ataxia type 17

por Weber, Jonasz Jeremiasz, Anger, Stefanie Cari, Pereira Sena, Priscila, Incebacak Eltemur, Rana Dilara, Huridou, Chrisovalantou, Fath, Florian, Gross, Caspar, Casadei, Nicolas, Riess, Olaf, Nguyen, Huu Phuc
Publicado 2022

The Endometrial Transcription Landscape of MRKH Syndrome

por Hentrich, Thomas, Koch, André, Weber, Nico, Kilzheimer, Alexander, Maia, Ana, Burkhardt, Simone, Rall, Katharina, Casadei, Nicolas, Kohlbacher, Oliver, Riess, Olaf, Schulze-Hentrich, Julia Maria, Brucker, Sara Yvonne
Publicado 2020

Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson’s disease patients

por Hentrich, Thomas, Wassouf, Zinah, Ehrhardt, Christine, Haas, Eva, Mills, James D., Aronica, Eleonora, Outeiro, Tiago Fleming, Hübener-Schmid, Jeannette, Riess, Olaf, Casadei, Nicolas, Schulze-Hentrich, Julia M.
Publicado 2020

Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in Vivo Genome Editing

por Pasquini, Giovanni, Cora, Virginia, Swiersy, Anka, Achberger, Kevin, Antkowiak, Lena, Müller, Brigitte, Wimmer, Tobias, Fraschka, Sabine Anne-Kristin, Casadei, Nicolas, Ueffing, Marius, Liebau, Stefan, Stieger, Knut, Busskamp, Volker
Publicado 2020

Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function

por Barbuti, Peter A., Ohnmacht, Jochen, Santos, Bruno F. R., Antony, Paul M., Massart, François, Cruciani, Gérald, Dording, Claire M., Pavelka, Lukas, Casadei, Nicolas, Kwon, Yong-Jun, Krüger, Rejko
Publicado 2021

Genomic surveillance of SARS-CoV-2 in the Republic of Congo

por Ntoumi, Francine, Mfoutou Mapanguy, Claujens Chastel, Tomazatos, Alexandru, Pallerla, Srinivas Reddy, Linh, Le Thi Kieu, Casadei, Nicolas, Angelov, Angel, Sonnabend, Michael, Peter, Silke, Kremsner, Peter G., Velavan, Thirumalaisamy P.
Publicado 2021