Identifying dominant modifiers of mutant FUS toxicity in vivo

por Daigle, J Gavin, Lanson, Nicholas A, Casci, Ian, Monaghan, John, Nichols, Charles, Kryndushkin, Dimitri, Shewmaker, Frank, Pandey, Udai
Publicado 2013

Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo

por Scaramuzzino, Chiara, Monaghan, John, Milioto, Carmelo, Lanson, Nicholas A., Maltare, Astha, Aggarwal, Tanya, Casci, Ian, Fackelmayer, Frank O., Pennuto, Maria, Pandey, Udai Bhan
Publicado 2013

Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy

por Scaramuzzino, Chiara, Casci, Ian, Parodi, Sara, Lievens, Patricia M.J., Polanco, Maria J., Milioto, Carmelo, Chivet, Mathilde, Monaghan, John, Mishra, Ashutosh, Badders, Nisha, Aggarwal, Tanya, Grunseich, Christopher, Sambataro, Fabio, Basso, Manuela, Fackelmayer, Frank O., Taylor, J. Paul, Pandey, Udai Bhan, Pennuto, Maria
Publicado 2015

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

por Marrone, Lara, Poser, Ina, Casci, Ian, Japtok, Julia, Reinhardt, Peter, Janosch, Antje, Andree, Cordula, Lee, Hyun O., Moebius, Claudia, Koerner, Ellen, Reinhardt, Lydia, Cicardi, Maria Elena, Hackmann, Karl, Klink, Barbara, Poletti, Angelo, Alberti, Simon, Bickle, Marc, Hermann, Andreas, Pandey, Udai Bhan, Hyman, Anthony A., Sterneckert, Jared L.
Publicado 2018

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

por Casci, Ian, Krishnamurthy, Karthik, Kour, Sukhleen, Tripathy, Vadreenath, Ramesh, Nandini, Anderson, Eric N., Marrone, Lara, Grant, Rogan A., Oliver, Stacie, Gochenaur, Lauren, Patel, Krishani, Sterneckert, Jared, Gleixner, Amanda M., Donnelly, Christopher J., Ruepp, Marc-David, Sini, Antonella M., Zuccaro, Emanuela, Pennuto, Maria, Pasinelli, Piera, Pandey, Udai Bhan
Publicado 2019