Modulation of imidazoline I(2) binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats

por Lanza, Marco, Ferrari, Flora, Menghetti, Ilaria, Tremolada, Dario, Caselli, Gianfranco
Publicado 2014

Modulation of NMDA receptor activity by CR4056, an imidazoline-2 receptor ligand with analgesic properties

por Puja, Giulia, Losi, Gabriele, Rovati, Lucio, Lanza, Marco, Caselli, Gianfranco, Bardoni, Rita
Publicado 2022

Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis

por Comi, Eleonora, Lanza, Marco, Ferrari, Flora, Mauri, Valeria, Caselli, Gianfranco, Rovati, Lucio Claudio
Publicado 2017

Efficacy of CR3294, a new benzamidine derivative, in the prevention of 5-fluorouracil-induced gastrointestinal mucositis and diarrhea in mice

por Letari, Ornella, Booth, Catherine, Bonazzi, Albino, Garofalo, Paolo, Makovec, Francesco, Rovati, Lucio C., Caselli, Gianfranco
Publicado 2009

Experimental Pharmacology of Glucosamine Sulfate

por Chiusaroli, Riccardo, Piepoli, Tiziana, Zanelli, Tiziano, Ballanti, Paola, Lanza, Marco, Rovati, Lucio C., Caselli, Gianfranco
Publicado 2011

Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain

por Ferrari, Flora, Fiorentino, Simonetta, Mennuni, Laura, Garofalo, Paolo, Letari, Ornella, Mandelli, Stefano, Giordani, Antonio, Lanza, Marco, Caselli, Gianfranco
Publicado 2011

I2-Imidazoline Ligand CR4056 Improves Memory, Increases ApoE Expression and Reduces BBB Leakage in 5xFAD Mice

por Mota, Bibiana C., Ashburner, Nathan, Abelleira-Hervas, Laura, Liu, Liyueyue, Aleksynas, Robertas, Rovati, Lucio Claudio, Caselli, Gianfranco, Sastre, Magdalena
Publicado 2022

Improved efficacy, tolerance, safety, and abuse liability profile of the combination of CR4056 and morphine over morphine alone in rodent models

por Sala, Emanuele, Ferrari, Flora, Lanza, Marco, Milia, Chiara, Sabatini, Chiara, Bonazzi, Albino, Comi, Eleonora, Borsi Franchini, Miriam, Caselli, Gianfranco, Rovati, Lucio Claudio
Publicado 2020

Development of Imidazole-Reactive Molecules Leading to a New Aggregation-Induced Emission Fluorophore Based on the Cinnamic Scaffold

por Razzano, Vincenzo, Paolino, Marco, Reale, Annalisa, Giuliani, Germano, Artusi, Roberto, Caselli, Gianfranco, Visintin, Michela, Makovec, Francesco, Donati, Alessandro, Villafiorita-Monteleone, Francesca, Botta, Chiara, Cappelli, Andrea
Publicado 2017

Ferulated Poly(vinyl alcohol) based hydrogels()

por Pepi, Simone, Paolino, Marco, Saletti, Mario, Venditti, Jacopo, Talarico, Luigi, Andreassi, Marco, Giuliani, Germano, Caselli, Gianfranco, Artusi, Roberto, Cappelli, Andrea, Leone, Gemma, Magnani, Agnese, Rovati, Lucio
Publicado 2023

CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats

por Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, GianFranco, Cavaletti, Guido
Publicado 2012

Poly-histidine grafting leading to fishbone-like architectures

por Razzano, Vincenzo, Paolino, Marco, Reale, Annalisa, Giuliani, Germano, Donati, Alessandro, Giorgi, Gianluca, Artusi, Roberto, Caselli, Gianfranco, Visintin, Michela, Makovec, Francesco, Battiato, Salvatore, Samperi, Filippo, Villafiorita-Monteleone, Francesca, Botta, Chiara, Cappelli, Andrea
Publicado 2018

Pharmacological characterisation of CR6086, a potent prostaglandin E(2) receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug

por Caselli, Gianfranco, Bonazzi, Albino, Lanza, Marco, Ferrari, Flora, Maggioni, Daniele, Ferioli, Cristian, Giambelli, Roberto, Comi, Eleonora, Zerbi, Silvia, Perrella, Marco, Letari, Ornella, Di Luccio, Elena, Colovic, Milena, Persiani, Stefano, Zanelli, Tiziano, Mennuni, Laura, Piepoli, Tiziana, Rovati, Lucio Claudio
Publicado 2018

Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells

por Bertini, Riccardo, Zack Howard, O.M., Dong, Hui-Fang, Oppenheim, Joost J., Bizzarri, Cinzia, Sergi, Rita, Caselli, Gianfranco, Pagliei, Sabrina, Romines, Brie, Wilshire, Jennifer A., Mengozzi, Manuela, Nakamura, Hajime, Yodoi, Junji, Pekkari, Klas, Gurunath, Ramanathan, Holmgren, Arne, Herzenberg, Leonore A., Herzenberg, Leonard A., Ghezzi, Pietro
Publicado 1999

A first-in-human trial on the safety and immunogenicity of COVID-eVax, a cellular response-skewed DNA vaccine against COVID-19

por Aurisicchio, Luigi, Brambilla, Nadia, Cazzaniga, Marina E., Bonfanti, Paolo, Milleri, Stefano, Ascierto, Paolo A., Capici, Serena, Vitalini, Cristina, Girolami, Federica, Giacovelli, Giampaolo, Caselli, Gianfranco, Visintin, Michela, Fanti, Francesca, Ghirri, Matteo, Conforti, Antonella, Compagnone, Mirco, Lione, Lucia, Salvatori, Erika, Pinto, Eleonora, Muzi, Alessia, Marra, Emanuele, Palombo, Fabio, Roscilli, Giuseppe, Manenti, Alessandro, Montomoli, Emanuele, Cadossi, Matteo, Rovati, Lucio C.
Publicado 2023

COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models

por Conforti, Antonella, Marra, Emanuele, Palombo, Fabio, Roscilli, Giuseppe, Ravà, Micol, Fumagalli, Valeria, Muzi, Alessia, Maffei, Mariano, Luberto, Laura, Lione, Lucia, Salvatori, Erika, Compagnone, Mirco, Pinto, Eleonora, Pavoni, Emiliano, Bucci, Federica, Vitagliano, Grazia, Stoppoloni, Daniela, Pacello, Maria Lucrezia, Cappelletti, Manuela, Ferrara, Fabiana Fosca, D’Acunto, Emanuela, Chiarini, Valerio, Arriga, Roberto, Nyska, Abraham, Di Lucia, Pietro, Marotta, Davide, Bono, Elisa, Giustini, Leonardo, Sala, Eleonora, Perucchini, Chiara, Paterson, Jemma, Ryan, Kathryn Ann, Challis, Amy-Rose, Matusali, Giulia, Colavita, Francesca, Caselli, Gianfranco, Criscuolo, Elena, Clementi, Nicola, Mancini, Nicasio, Groß, Rüdiger, Seidel, Alina, Wettstein, Lukas, Münch, Jan, Donnici, Lorena, Conti, Matteo, De Francesco, Raffaele, Kuka, Mirela, Ciliberto, Gennaro, Castilletti, Concetta, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Guidotti, Luca G., Rovati, Lucio, Iannacone, Matteo, Aurisicchio, Luigi
Publicado 2022