Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP(3)

por Cash, Jennifer N., Sharma, Prateek V., Tesmer, John J.G.
Publicado 2018

High-resolution cryo-EM using beam-image shift at 200 keV

por Cash, Jennifer N., Kearns, Sarah, Li, Yilai, Cianfrocco, Michael A.
Publicado 2020

Long-Term Outcomes for Patients with Prostate Cancer Having Intermediate and High-Risk Disease, Treated with Combination External Beam Irradiation and Brachytherapy

por Dattoli, Michael, Wallner, Kent, True, Lawrence, Bostwick, David, Cash, Jennifer, Sorace, Richard
Publicado 2010

Structural and dynamic changes in P-Rex1 upon activation by PIP(3) and inhibition by IP(4)

por Ravala, Sandeep K., Adame-Garcia, Sendi Rafael, Li, Sheng, Chen, Chun-Liang, Cianfrocco, Michael A., Gutkind, J. Silvio, Cash, Jennifer N., Tesmer, John J. G.
Publicado 2023

Cryo–electron microscopy structure and analysis of the P-Rex1–Gβγ signaling scaffold

por Cash, Jennifer N., Urata, Sarah, Li, Sheng, Ravala, Sandeep K., Avramova, Larisa V., Shost, Michael D., Gutkind, J. Silvio, Tesmer, John J. G., Cianfrocco, Michael A.
Publicado 2019

Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolam...

por Lu, Tsan-Wen, Aoto, Phillip C., Weng, Jui-Hung, Nielsen, Cole, Cash, Jennifer N., Hall, James, Zhang, Ping, Simon, Sanford M., Cianfrocco, Michael A., Taylor, Susan S.
Publicado 2020

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1

por Bandekar, Sumit J., Chen, Chun-Liang, Ravala, Sandeep K., Cash, Jennifer N., Avramova, Larisa V., Zhalnina, Mariya V., Gutkind, J. Silvio, Li, Sheng, Tesmer, John J.G.
Publicado 2022