Passive immunotherapies targeting Aβ and tau in Alzheimer's disease

por Plotkin, Steven S., Cashman, Neil R.
Publicado 2020

Human Retrovirus and Multiple Sclerosis

por Antel, Jack P., Cashman, Neil R.
Publicado 1991

Selenium-based compounds: Emerging players in the ever-unfolding story of SOD1 in amyotrophic lateral sclerosis.

por Yerbury, Justin J., Cashman, Neil R.
Publicado 2020

TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion

por Pokrishevsky, Edward, Grad, Leslie I., Cashman, Neil R.
Publicado 2016

Emerging Developments in Targeting Proteotoxicity in Neurodegenerative Diseases

por McAlary, Luke, Plotkin, Steven S., Cashman, Neil R.
Publicado 2019

Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding

por Grad, Leslie I, Pokrishevsky, Edward, Silverman, Judith M, Cashman, Neil R
Publicado 2014

Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells

por Pokrishevsky, Edward, Hong, Ran Ha, Mackenzie, Ian R., Cashman, Neil R.
Publicado 2017

Initial Structural Models of the Aβ42 Dimer from Replica Exchange Molecular Dynamics Simulations

por Blinov, Nikolay, Khorvash, Massih, Wishart, David S., Cashman, Neil R., Kovalenko, Andriy
Publicado 2017

Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

por McAlary, Luke, Plotkin, Steven S., Yerbury, Justin J., Cashman, Neil R.
Publicado 2019

Corrigendum: Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

por McAlary, Luke, Plotkin, Steven S., Yerbury, Justin J., Cashman, Neil R.
Publicado 2020

Nanopore Analysis of Wild-Type and Mutant Prion Protein (PrP(C)): Single Molecule Discrimination and PrP(C) Kinetics

por Jetha, Nahid N., Semenchenko, Valentyna, Wishart, David S., Cashman, Neil R., Marziali, Andre
Publicado 2013

Intermediate CAG Repeat Expansion in the ATXN2 Gene Is a Unique Genetic Risk Factor for ALS−A Systematic Review and Meta-Analysis of Observational Studies

por Wang, Ming-Dong, Gomes, James, Cashman, Neil R., Little, Julian, Krewski, Daniel
Publicado 2014

A Meta-Analysis of Observational Studies of the Association Between Chronic Occupational Exposure to Lead and Amyotrophic Lateral Sclerosis

por Wang, Ming-Dong, Gomes, James, Cashman, Neil R., Little, Julian, Krewski, Daniel
Publicado 2014

A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria

por Peng, Xubiao, Gibbs, Ebrima, Silverman, Judith M, Cashman, Neil R, Plotkin, Steven S
Publicado 2021

P2X7 receptor activation mediates superoxide dismutase 1 (SOD1) release from murine NSC-34 motor neurons

por Bartlett, Rachael, Ly, Diane, Cashman, Neil R., Sluyter, Ronald, Yerbury, Justin J.
Publicado 2022

Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS

por Ryu, Hoon, Jeon, Gye Sun, Cashman, Neil R., Kowall, Neil W., Lee, Junghee
Publicado 2011

Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis

por Pokrishevsky, Edward, Grad, Leslie I., Yousefi, Masoud, Wang, Jing, Mackenzie, Ian R., Cashman, Neil R.
Publicado 2012

Sublethal enteroviral infection exacerbates disease progression in an ALS mouse model

por Xue, Yuan Chao, Liu, Huitao, Mohamud, Yasir, Bahreyni, Amirhossein, Zhang, Jingchun, Cashman, Neil R., Luo, Honglin
Publicado 2022

Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide “Glycindel” Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for P...

por Hsueh, Shawn C. C., Aina, Adekunle, Roman, Andrei Yu., Cashman, Neil R., Peng, Xubiao, Plotkin, Steven S.
Publicado 2022

Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells

por Pokrishevsky, Edward, McAlary, Luke, Farrawell, Natalie E., Zhao, Beibei, Sher, Mine, Yerbury, Justin J., Cashman, Neil R.
Publicado 2018