Herpesvirus Vectors for Therapy of Brain Tumors

por Cassady, Kevin A, Parker, Jacqueline Nuss
Publicado 2010

STING Restricts oHSV Replication and Spread in Resistant MPNSTs but Is Dispensable for Basal IFN-Stimulated Gene Upregulation

por Lee, Joel M., Ghonime, Mohammed G., Cassady, Kevin A.
Publicado 2019

The Antiviral Apparatus: STING and Oncolytic Virus Restriction

por Lee, Joel, Ghonime, Mohammed G., Wang, Ruoning, Cassady, Kevin A.
Publicado 2019

Spontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response

por Shah, Amish C., Parker, Jacqueline N., Shimamura, Masako, Cassady, Kevin A.
Publicado 2009

Human Herpesviridae Methods of Natural Killer Cell Evasion

por Odom, Carl I., Gaston, David C., Markert, James M., Cassady, Kevin A.
Publicado 2012

Oncolytic Virus-Based Cytokine Expression to Improve Immune Activity in Brain and Solid Tumors

por Pearl, Taylor M., Markert, James M., Cassady, Kevin A., Ghonime, Mohammed G.
Publicado 2019

To Infection and Beyond: The Multi-Pronged Anti-Cancer Mechanisms of Oncolytic Viruses

por Cassady, Kevin A., Haworth, Kellie B., Jackson, Josh, Markert, James M., Cripe, Timothy P.
Publicado 2016

Targeting Pediatric Cancer Stem Cells with Oncolytic Virotherapy

por Friedman, Gregory K., Cassady, Kevin A., Beierle, Elizabeth A., Markert, James M., Gillespie, G. Yancey
Publicado 2012

Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy

por Friedman, Gregory K., Raborn, Joel, Kelly, Virginia M., Cassady, Kevin A., Markert, James M., Gillespie, G. Yancey
Publicado 2013

Immunotherapies for pediatric cancer: current landscape and future perspectives

por Hutzen, Brian, Paudel, Siddhi Nath, Naeimi Kararoudi, Meisam, Cassady, Kevin A., Lee, Dean A., Cripe, Timothy P.
Publicado 2019

Pediatric versus adult high grade glioma: Immunotherapeutic and genomic considerations

por Aggarwal, Payal, Luo, Wen, Pehlivan, Katherine C., Hoang, Hai, Rajappa, Prajwal, Cripe, Timothy P., Cassady, Kevin A., Lee, Dean A., Cairo, Mitchell S.
Publicado 2022

Production of Bioactive Soluble Interleukin-15 in Complex with Interleukin-15 Receptor Alpha from a Conditionally-Replicating Oncolytic HSV-1

por Gaston, David C., Odom, Carl I., Li, Li, Markert, James M., Roth, Justin C., Cassady, Kevin A., Whitley, Richard J., Parker, Jacqueline N.
Publicado 2013

Pre-clinical Assessment of C134, a Chimeric Oncolytic Herpes Simplex Virus, in Mice and Non-human Primates

por Cassady, Kevin A., Bauer, David F., Roth, Justin, Chambers, Melissa R., Shoeb, Trent, Coleman, Jennifer, Prichard, Mark, Gillespie, G. Yancey, Markert, James M.
Publicado 2017

High Mobility Group Box 1 Influences HSV1716 Spread and Acts as an Adjuvant to Chemotherapy

por Sprague, Leslee, Lee, Joel M., Hutzen, Brian J., Wang, Pin-Yi, Chen, Chun-Yu, Conner, Joe, Braidwood, Lynne, Cassady, Kevin A., Cripe, Timothy P.
Publicado 2018

Chimeric HCMV/HSV-1 and Δγ(1)34.5 oncolytic herpes simplex virus elicit immune mediated antigliomal effect and antitumor memory()()

por Ghonime, Mohammed G., Jackson, Josh, Shah, Amish, Roth, Justin, Li, Mao, Saunders, Ute, Coleman, Jennifer, Gillespie, G. Yancey, Markert, James M., Cassady, Kevin A.
Publicado 2017

Immunotherapeutic Challenges for Pediatric Cancers

por Hutzen, Brian, Ghonime, Mohammed, Lee, Joel, Mardis, Elaine R., Wang, Ruoning, Lee, Dean A., Cairo, Mitchell S., Roberts, Ryan D., Cripe, Timothy P., Cassady, Kevin A.
Publicado 2019

Myelolytic Treatments Enhance Oncolytic Herpes Virotherapy in Models of Ewing Sarcoma by Modulating the Immune Microenvironment

por Denton, Nicholas L., Chen, Chun-Yu, Hutzen, Brian, Currier, Mark A., Scott, Thomas, Nartker, Brooke, Leddon, Jennifer L., Wang, Pin-Yi, Srinivas, Rachelle, Cassady, Kevin A., Goins, William F., Cripe, Timothy P.
Publicado 2018

γ(1)34.5-Deleted HSV-1 Expressing Human Cytomegalovirus IRS1 Gene Kills Human Glioblastoma Cells as Efficiently as Wild-type HSV-1 in Normoxia or Hypoxia

por Friedman, Gregory K., Nan, Li, Haas, Marilyn C., Kelly, Virginia M., Moore, Blake P., Langford, Catherine P., Xu, Hui, Han, Xiaosi, Beierle, Elizabeth A., Markert, James M., Cassady, Kevin A., Gillespie, G. Yancey
Publicado 2014

Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy

por Ghonime, Mohammed G, Saini, Uksha, Kelly, Michael C, Roth, Justin C, Wang, Pin-Yi, Chen, Chun-Yu, Miller, Katherine, Hernandez-Aguirre, Ilse, Kim, Yeaseul, Mo, Xiaokui, Stanek, Joseph R, Cripe, Tim, Mardis, Elaine, Cassady, Kevin A
Publicado 2021

Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses of a Phase IB Study

por Miller, Katherine E., Cassady, Kevin A., Roth, Justin C., Clements, Jennifer, Schieffer, Kathleen M., Leraas, Kristen, Miller, Anthony R., Prasad, Nripesh, Leavenworth, Jianmei W., Aban, Inmaculada B., Whitley, Richard J., Gillespie, G. Yancey, Mardis, Elaine R., Markert, James M.
Publicado 2022