Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway

por Panarsky, Rony, Crooks, Daniel R., Lane, Andrew N., Yang, Youfeng, Cassel, Teresa A., Fan, Teresa W.-M., Linehan, W. Marston, Moscow, Jeffrey A.
Publicado 2020

A Micro-Scale Analytical Method for Determining Glycogen Turnover by NMR and FTMS

por Scott, Timothy L., Zhu, Juan, Cassel, Teresa A., Vicente-Muñoz, Sara, Lin, Penghui, Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M.
Publicado 2022

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

por Wu, Heng, Kren, Betsy T., Lane, Andrew N., Cassel, Teresa A., Higashi, Richard M., Fan, Teresa W.M., Scaria, George S., Shekels, Laurie L., Klein, Mark A., Albrecht, Jeffrey H.
Publicado 2023

In vivo deep network tracing reveals phosphofructokinase-mediated coordination of biosynthetic pathway activity in the myocardium

por Fulghum, Kyle L., Audam, Timothy N., Lorkiewicz, Pawel K., Zheng, Yuting, Merchant, Michael, Cummins, Timothy D., Dean, William L., Cassel, Teresa A., Fan, Teresa W. M., Hill, Bradford G.
Publicado 2022

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation

por Lian, Gaojian, Gnanaprakasam, JN Rashida, Wang, Tingting, Wu, Ruohan, Chen, Xuyong, Liu, Lingling, Shen, Yuqing, Yang, Mao, Yang, Jun, Chen, Ying, Vasiliou, Vasilis, Cassel, Teresa A, Green, Douglas R, Liu, Yusen, Fan, Teresa WM, Wang, Ruoning
Publicado 2018

Asparagine restriction enhances CD8(+) T cell metabolic fitness and antitumoral functionality through an NRF2-dependent stress response

por Gnanaprakasam, J. N. Rashida, Kushwaha, Bhavana, Liu, Lingling, Chen, Xuyong, Kang, Siwen, Wang, Tingting, Cassel, Teresa A., Adams, Christopher M., Higashi, Richard M., Scott, David A., Xin, Gang, Li, Zihai, Yang, Jun, Lane, Andrew N., Fan, Teresa W.-M., Zhang, Ji, Wang, Ruoning
Publicado 2023

Inosine is an alternative carbon source for CD8(+)-T-cell function under glucose restriction

por Wang, Tingting, Gnanaprakasam, J. N. Rashida, Chen, Xuyong, Kang, Siwen, Xu, Xuequn, Sun, Hua, Liu, Lingling, Rodgers, Hayley, Miller, Ethan, Cassel, Teresa A., Sun, Qiushi, Vicente-Muñoz, Sara, Warmoes, Marc O., Lin, Penghui, Piedra-Quintero, Zayda Lizbeth, Guerau-de-Arellano, Mireia, Cassady, Kevin A., Zheng, Song Guo, Yang, Jun, Lane, Andrew N., Song, Xiaotong, Fan, Teresa W.-M., Wang, Ruoning
Publicado 2020