Correction of aging phenotype in the liver

por Rodriguez, Katherine, Cast, Ashley, Timchenko, Nikolai A.
Publicado 2018

PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma

por Valanejad, Leila, Cast, Ashley, Wright, Mary, Bissig, Karl-Dimiter, Karns, Rebekah, Weirauch, Matthew T., Timchenko, Nikolai
Publicado 2018

Liver Proliferation Is an Essential Driver of Fibrosis in Mouse Models of Nonalcoholic Fatty Liver Disease

por Cast, Ashley, Kumbaji, Meenasri, D'Souza, Amber, Rodriguez, Katherine, Gupta, Anita, Karns, Rebekah, Timchenko, Lubov, Timchenko, Nikolai
Publicado 2019

Small Molecule Cjoc42 Improves Chemo-Sensitivity and Increases Levels of Tumor Suppressor Proteins in Hepatoblastoma Cells and in Mice by Inhibiting Oncogene Gankyrin

por D’Souza, Amber M., Cast, Ashley, Kumbaji, Meenasri, Rivas, Maria, Gulati, Ruhi, Johnston, Michael, Smithrud, David, Geller, James, Timchenko, Nikolai
Publicado 2021

Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-C/EBPα-p300 Axis

por Nguyen, Phuong, Valanejad, Leila, Cast, Ashley, Wright, Mary, Garcia, Jose M., El-Serag, Hashem B., Karns, Rebekah, Timchenko, Nikolai A.
Publicado 2018

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation

por D’Souza, Amber M., Jiang, Yanjun, Cast, Ashley, Valanejad, Leila, Wright, Mary, Lewis, Kyle, Kumbaji, Meenasri, Shah, Sheeniza, Smithrud, David, Karns, Rebekah, Shin, Soona, Timchenko, Nikolai
Publicado 2018

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation

por Schaub, Johanna R., Huppert, Kari A., Kurial, Simone N. T., Hsu, Bernadette Y., Cast, Ashley E., Donnelly, Bryan, Karns, Rebekah A., Chen, Feng, Rezvani, Milad, Luu, Hubert Y., Mattis, Aras N., Rougemont, Anne-Laure, Rosenthal, Philip, Huppert, Stacey S., Willenbring, Holger
Publicado 2018

β‐catenin cancer–enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma

por Gulati, Ruhi, Johnston, Michael, Rivas, Maria, Cast, Ashley, Kumbaji, Meenasri, Hanlon, Margaret A., Lee, Sanghoon, Zhou, Ping, Lake, Charissa, Schepers, Emily, Min, Kyung‐Won, Yoon, Je‐Hyun, Karns, Rebekah, Reid, Lola M., Lopez‐Terrada, Dolores, Timchenko, Lubov, Parameswaran, Sreeja, Weirauch, Matthew T., Ranganathan, Sarangarajan, Bondoc, Alexander, Geller, James, Tiao, Gregory, Shin, Soona, Timchenko, Nikolai
Publicado 2022