Correction to: Crystal structure of PKG Iβ holoenzyme reveals a trans‑inhibiting dimer assembly

por Kim, Choel, Sharma, Rajesh, Casteel, Darren E.
Publicado 2020

Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3

por Hu, Tingfei, Kalyanaraman, Hema, Pilz, Renate B., Casteel, Darren E.
Publicado 2023

cGMP-dependent protein kinase Iβ phosphorylates and regulates the function of the actin/myosin-associated protein caldesmon

por Casteel, Darren E, Schwappacher, Raphaela, Rangaswami, Hema, Su-Yuo, Jacqueline
Publicado 2013

PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells

por Aminzai, Sahar, Hu, Tingfei, Pilz, Renate B., Casteel, Darren E.
Publicado 2022

Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells

por Haushalter, Kristofer J., Casteel, Darren E., Raffeiner, Andrea, Stefan, Eduard, Patel, Hemal H., Taylor, Susan S.
Publicado 2018

Src activation by cGMP/PKG II in osteoblasts: characterization of a mechano-sensitive signalling complex

por Rangaswami, Hema, Schwappacher, Raphaela, Marathe, Nisha, Casteel, Darren E, Haas, Bodo, Pfeifer, Alexander, Shattil, Sanford, Boss, Gerry, Pilz, Renate B
Publicado 2011

The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring

por Casteel, Darren E, Smith-Nguyen, Eric V, Sankaran, Banumathi, Spraggon, Glen, Hampton, Eric N, Pilz, Renate B, Taylor, Susan S, Kim, Choel
Publicado 2009

Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity

por Wahwah, Nisreen, Dhar, Debanjan, Chen, Hui, Zhuang, Shunhui, Chan, Adriano, Casteel, Darren E., Kalyanaraman, Hema, Pilz, Renate B., Boss, Gerry R.
Publicado 2020

Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

por Kim, Jeong Joo, Casteel, Darren E., Huang, Gilbert, Kwon, Taek Hun, Ren, Ronnie Kuo, Zwart, Peter, Headd, Jeffrey J., Brown, Nicholas Gene, Chow, Dar-Chone, Palzkill, Timothy, Kim, Choel
Publicado 2011

The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding

por Kim, Jeong Joo, Casteel, Darren E, Huang, Gilbert, Kwon, Taek Hun, Ren, Ronnie Kuo, Zwart, Peter, Headd, Jeffrey J, Brown, Nicholas Gene, Chow, Dar-Chone, Palzkill, Timothy, Kim, Choel
Publicado 2011

An auto-inhibited state of protein kinase G and implications for selective activation

por Sharma, Rajesh, Kim, Jeong Joo, Qin, Liying, Henning, Philipp, Akimoto, Madoka, VanSchouwen, Bryan, Kaur, Gundeep, Sankaran, Banumathi, MacKenzie, Kevin R, Melacini, Giuseppe, Casteel, Darren E, Herberg, Friedrich W, Kim, Choel
Publicado 2022

Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice

por Chang, Stephen, Tat, John, China, Shyamsundar Pal, Kalyanaraman, Hema, Zhuang, Shunhui, Chan, Adriano, Lai, Cassandra, Radic, Zoran, Abdel-Rahman, Engy A, Casteel, Darren E, Pilz, Renate B, Ali, Sameh S, Boss, Gerry R
Publicado 2022

Structures of human PKG reveal cGMP-selectived activation mechanisms

por Huang, Gilbert Y, Kim, Jeong J, Reger, Albert S, Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E, Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W, Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W, Kim, Choel
Publicado 2013

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B(12) analog

por Schwaerzer, Gerburg K., Kalyanaraman, Hema, Casteel, Darren E., Dalton, Nancy D., Gu, Yusu, Lee, Seunghoe, Zhuang, Shunhui, Wahwah, Nisreen, Schilling, Jan M., Patel, Hemal H., Zhang, Qian, Makino, Ayako, Milewicz, Dianna M., Peterson, Kirk L., Boss, Gerry R., Pilz, Renate B.
Publicado 2019

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications: Bamberg, Germany. 23-25 June, 2017

por Todd Milne, G., Sandner, Peter, Lincoln, Kathleen A., Harrison, Paul C., Chen, Hongxing, Wang, Hong, Clifford, Holly, Qian, Hu Sheng, Wong, Diane, Sarko, Chris, Fryer, Ryan, Richman, Jeremy, Reinhart, Glenn A., Boustany, Carine M., Pullen, Steven S., Andresen, Henriette, Moltzau, Lise Román, Cataliotti, Alessandro, Levy, Finn Olav, Lukowski, Robert, Frankenreiter, Sandra, Friebe, Andreas, Calamaras, Timothy, Baumgartner, Robert, McLaughlin, Angela, Aronovitz, Mark, Baur, Wendy, Wang, Guang-Rong, Kapur, Navin, Karas, Richard, Blanton, Robert, Hell, Stefan, Waldman, Scott A., Lin, Jieru E., Colon-Gonzalez, Francheska, Kim, Gilbert W., Blomain, Erik S., Merlino, Dante, Snook, Adam, Erdmann, Jeanette, Wobst, Jana, Kessler, Thorsten, Schunkert, Heribert, Walter, Ulrich, Pagel, Oliver, Walter, Elena, Gambaryan, Stepan, Smolenski, Albert, Jurk, Kerstin, Zahedi, Rene, Klinger, James R., Benza, Raymond L., Corris, Paul A., Langleben, David, Naeije, Robert, Simonneau, Gérald, Meier, Christian, Colorado, Pablo, Chang, Mi Kyung, Busse, Dennis, Hoeper, Marius M., Masferrer, Jaime L., Jacobson, Sarah, Liu, Guang, Sarno, Renee, Bernier, Sylvie, Zhang, Ping, Todd Milne, G., Flores-Costa, Roger, Currie, Mark, Hall, Katherine, Möhrle, Dorit, Reimann, Katrin, Wolter, Steffen, Wolters, Markus, Mergia, Evanthia, Eichert, Nicole, Geisler, Hyun-Soon, Ruth, Peter, Friebe, Andreas, Feil, Robert, Zimmermann, Ulrike, Koesling, Doris, Knipper, Marlies, Rüttiger, Lukas, Tanaka, Yasutake, Okamoto, Atsuko, Nojiri, Takashi, Kumazoe, Motofumi, Tokudome, Takeshi, Miura, Koichi, Hino, Jun, Hosoda, Hiroshi, Miyazato, Mikiya, Kangawa, Kenji, Kapil, Vikas, Ahluwalia, Amrita, Paolocci, Nazareno, Eaton, Philip, Campbell, James C., Henning, Philipp, Franz, Eugen, Sankaran, Banumathi, Herberg, Friedrich W., Kim, Choel, Wittwer, M., Luo, Q., Kaila, V., Dames, S. A., Tobin, Andrew, Alam, Mahmood, Rudyk, Olena, Krasemann, Susanne, Hartmann, Kristin, Prysyazhna, Oleksandra, Zhang, Min, Zhao, Lan, Weiss, Astrid, Schermuly, Ralph, Eaton, Philip, Moyes, Amie J., Chu, Sandy M., Baliga, Reshma S., Hobbs, Adrian J., Michalakis, Stylianos, Mühlfriedel, Regine, Schön, Christian, Fischer, Dominik M., Wilhelm, Barbara, Zobor, Ditta, Kohl, Susanne, Peters, Tobias, Zrenner, Eberhart, Bartz-Schmidt, Karl Ulrich, Ueffing, Marius, Wissinger, Bernd, Seeliger, Mathias, Biel, Martin, Ranek, Mark J., Kokkonen, Kristen M., Lee, Dong I., Holewinski, Ronald J., Agrawal, Vineet, Virus, Cornelia, Stevens, Donté A., Sasaki, Masayuki, Zhang, Huaqun, Mannion, Mathew M., Rainer, Peter P., Page, Richard C., Schisler, Jonathan C., Van Eyk, Jennifer E., Willis, Monte S., Kass, David A., Zaccolo, Manuela, Russwurm, Michael, Giesen, Jan, Russwurm, Corina, Füchtbauer, Ernst-Martin, Koesling, Doris, Bork, Nadja I., Nikolaev, Viacheslav O., Agulló, Luis, Floor, Martin, Villà-Freixa, Jordi, Manfra, Ornella, Calamera, Gaia, Surdo, Nicoletta C., Meier, Silja, Froese, Alexander, Nikolaev, Viacheslav O., Zaccolo, Manuela, Levy, Finn Olav, Andressen, Kjetil Wessel, Aue, Annemarie, Schwiering, Fabian, Groneberg, Dieter, Friebe, Andreas, Bajraktari, Gzona, Burhenne, Jürgen, Haefeli, Walter E., Weiss, Johanna, Beck, Katharina, Voussen, Barbara, Vincent, Alexander, Parsons, Sean P., Huizinga, Jan D., Friebe, Andreas, Mónica, Fabiola Zakia, Seto, Edward, Murad, Ferid, Bian, Ka, Burgoyne, Joseph R., Prysyazhna, Oleksandra, Richards, Daniel, Eaton, Philip, Calamera, Gaia, Bjørnerem, Marianne, Ulsund, Andrea Hembre, Kim, Jeong Joo, Kim, Choel, Levy, Finn Olav, Andressen, Kjetil Wessel, Donzelli, Sonia, Goetz, Mara, Schmidt, Kjestine, Wolters, Markus, Stathopoulou, Konstantina, Prysyazhna, Oleksandra, Scotcher, Jenna, Dees, Christian, Subramanian, Hariharan, Butt, Elke, Kamynina, Alisa, Bruce King, S., Nikolaev, Viacheslav O., de Witt, Cor, Leichert, Lars I., Feil, Robert, Eaton, Philip, Cuello, Friederike, Dobrowinski, Hyazinth, Lehners, Moritz, Schmidt, Michael Paolillo Hannes, Feil, Robert, Feil, Susanne, Wen, Lai, Wolters, Markus, Thunemann, Martin, Schmidt, Kjestine, Olbrich, Marcus, Langer, Harald, Gawaz, Meinrad, Friebe, Andreas, de Wit, Cor, Feil, Robert, Franz, Eugen, Kim, Jeong Joo, Bertinetti, Daniela, Kim, Choel, Herberg, Friedrich W., Ghofrani, Hossein-Ardeschir, Grimminger, Friedrich, Grünig, Ekkehard, Huang, Yigao, Jansa, Pavel, Jing, Zhi Cheng, Kilpatrick, David, Langleben, David, Rosenkranz, Stephan, Menezes, Flavia, Fritsch, Arno, Nikkho, Sylvia, Frey, Reiner, Humbert, Marc, Groneberg, Dieter, Aue, Annemarie, Schwiering, Fabian, Friebe, Andreas, Harloff, Manuela, Reinders, Joerg, Schlossmann, Jens, Jung, Joon, Wales, Jessica A., Chen, Cheng-Yu, Breci, Linda, Weichsel, Andrzej, Bernier, Sylvie G., Solinga, Robert, Sheppeck, James E., Renhowe, Paul A., Montfort, William R., Qin, Liying, Sung, Ying-Ju, Casteel, Darren, Kim, Choel, Kollau, Alexander, Neubauer, Andrea, Schrammel, Astrid, Russwurm, Michael, Koesling, Doris, Mayer, Bernd, Kumazoe, Motofumi, Takai, Mika, Takeuchi, Chieri, Kadomatsu, Mai, Hiroi, Shun, Takamatsu, Kanako, Nojiri, Takashi, Kangawa, Kenji, Tachibana, Hirofumi, Opelt, Marissa, Eroglu, Emrah, Waldeck-Weiermair, Markus, Russwurm, Michael, Koesling, Doris, Malli, Roland, Graier, Wolfgang F., Fassett, John T., Schrammel, Astrid, Mayer, Bernd, Sollie, Selene J., Moltzau, Lise Román, Hernandez-Valladares, Maria, Berven, Frode, Levy, Finn Olav, Andressen, Kjetil W., Nojiri, Takashi, Tokudome, Takeshi, Kumazoe, Motofumi, Arai, Miki, Suzuki, Yutaka, Miura, Koichi, Hino, Jun, Hosoda, Hiroshi, Miyazato, Mikiya, Okumura, Meinoshin, Kawaoka, Shinpei, Kangawa, Kenji, Peters, Stefanie, Schmidt, Hannes, Selin Kenet, B., Nies, Sarah Helena, Frank, Katharina, Wen, Lai, Rathjen, Fritz G., Feil, Robert, Petrova, Olga N., Lamarre, Isabelle, Négrerie, Michel, Robinson, Jerid W., Egbert, Jeremy R., Davydova, Julia, Jaffe, Laurinda A., Potter, Lincoln R., Robinson, Jerid W., Blixt, Nicholas, Shuhaibar, Leia C., Warren, Gordon L., Mansky, Kim C., Jaffe, Laurinda A., Potter, Lincoln R., Romoli, Simone, Bauch, Tobias, Dröbner, Karoline, Eitner, Frank, Ruppert, Mihály, Radovits, Tamás, Korkmaz-Icöz, Sevil, Li, Shiliang, Hegedűs, Péter, Loganathan, Sivakanan, Németh, Balázs Tamás, Oláh, Attila, Mátyás, Csaba, Benke, Kálmán, Merkely, Béla, Karck, Matthias, Szabó, Gábor, Scheib, Ulrike, Broser, Matthias, Mukherjee, Shatanik, Stehfest, Katja, Gee, Christine E., Körschen, Heinz G., Oertner, Thomas G., Hegemann, Peter, Schmidt, Hannes, Dickey, Deborah M., Dumoulin, Alexandre, Kühn, Ralf, Jaffe, Laurinda, Potter, Lincoln R., Rathjen, Fritz G., Schobesberger, Sophie, Wright, Peter, Poulet, Claire, Mansfield, Catherine, Friebe, Andreas, Harding, Sian E., Nikolaev, Viacheslav O., Gorelik, Julia, Kollau, Alexander, Opelt, Marissa, Wölkart, Gerald, Gorren, Antonius C. F., Russwurm, Michael, Koesling, Doris, Schrammel, Astrid, Mayer, Bernd, Schwaerzer, Gerburg K., Casteel, Darren E., Dalton, Nancy D., Gu, Yusu, Zhuang, Shunhui, Milewicz, Dianna M., Peterson, Kirk L., Pilz, Renate, Schwiering, Fabian, Aue, Annemarie, Groneberg, Dieter, Friebe, Andreas, Argyriou, Aikaterini I., Makrynitsa, Garyfalia, Alexandropoulos, Ioannis I., Stamopoulou, Andriana, Bantzi, Marina, Giannis, Athanassios, Topouzis, Stavros, Papapetropoulos, Andreas, Spyroulias, Georgios A., Stuehr, Dennis J., Ghosh, Arnab, Dai, Yue, Misra, Saurav, Tchernychev, Boris, Jung, Joon, Liu, Guang, Silos-Santiago, Inmaculada, Hannig, Gerhard, Dao, Vu Thao-Vi, Deile, Martin, Nedvetsky, Pavel I., Güldner, Andreas, Ibarra-Alvarado, César, Gödecke, Axel, Schmidt, Harald H. H. W., Vachaviolos, Angelos, Gerling, Andrea, Thunemann, Martin, Lutz, Stefan Z., Häring, Hans-Ulrich, Krüger, Marcel A., Pichler, Bernd J., Shipston, Michael J., Feil, Susanne, Feil, Robert, Vandenwijngaert, Sara, Ledsky, Clara D., Agha, Obiajulu, Hu, Dongjian, Domian, Ibrahim J., Buys, Emmanuel S., Newton-Cheh, Christopher, Bloch, Donald B., Voussen, Barbara, Beck, Katharina, Mauro, Nadine, Keppler, Jonas, Friebe, Andreas, Ferreira, Wilson A., Chweih, Hanan, Brito, Pamela L., Almeida, Camila B., Penteado, Carla F. F., Saad, Sara S. O., Costa, Fernando F., Frenette, Paul S., Brockschnieder, Damian, Stasch, Johannes-Peter, Sandner, Peter, Conran, Nicola, Zimmer, Daniel P., Tobin, Jenny, Shea, Courtney, Sarno, Renee, Long, Kimberly, Jacobson, Sarah, Tang, Kim, Germano, Peter, Wakefield, James, Banijamali, Ali, Im, G-Yoon Jamie, Sheppeck, James E., Profy, Albert T., Todd Milne, G., Currie, Mark G., Masferrer, Jaime L.
Publicado 2017