Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients

por Thiel, Christoph, Cordes, Henrik, Conde, Isabel, Castell, José Vicente, Blank, Lars Mathias, Kuepfer, Lars
Publicado 2016

The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes

por Martínez-Sena, Teresa, Soluyanova, Polina, Guzmán, Carla, Valdivielso, José Manuel, Castell, José Vicente, Jover, Ramiro
Publicado 2020

Factors that influence the quality of metabolomics data in in vitro cell toxicity studies: a systematic survey

por Moreno-Torres, Marta, García-Llorens, Guillem, Moro, Erika, Méndez, Rebeca, Quintás, Guillermo, Castell, José Vicente
Publicado 2021

Foxa1 Reduces Lipid Accumulation in Human Hepatocytes and Is Down-Regulated in Nonalcoholic Fatty Liver

por Moya, Marta, Benet, Marta, Guzmán, Carla, Tolosa, Laia, García-Monzón, Carmelo, Pareja, Eugenia, Castell, José Vicente, Jover, Ramiro
Publicado 2012

Transplantation of hESC-derived hepatocytes protects mice from liver injury

por Tolosa, Laia, Caron, Jérôme, Hannoun, Zara, Antoni, Marc, López, Silvia, Burks, Deborah, Castell, Jose Vicente, Weber, Anne, Gomez-Lechon, Maria-Jose, Dubart-Kupperschmitt, Anne
Publicado 2015

Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen

por Rodríguez-Agudo, Rubén, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Fernández-Tussy, Pablo, Fernández-Ramos, David, Lachiondo-Ortega, Sofía, González-Recio, Irene, Gil-Pitarch, Clàudia, Mercado-Gómez, María, Morán, Laura, Bizkarguenaga, Maider, Lopitz-Otsoa, Fernando, Petrov, Petar, Bravo, Miren, Van Liempd, Sebastiaan Martijn, Falcon-Perez, Juan Manuel, Zabala-Letona, Amaia, Carracedo, Arkaitz, Castell, Jose Vicente, Jover, Ramiro, Martínez-Cruz, Luis Alfonso, Delgado, Teresa Cardoso, Cubero, Francisco Javier, Lucena, María Isabel, Andrade, Raúl Jesús, Mabe, Jon, Simón, Jorge, Martínez-Chantar, María Luz
Publicado 2022