Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

por Morin, Aurélie, Ruggiero, Carmen, Robidel, Estelle, Doghman-Bouguerra, Mabrouka, Das, Atze T., Castellano, Rémy, Josselin, Emmanuelle, Favier, Judith, Lalli, Enzo
Publicado 2017

Antimicrobial and cytotoxic effects of marine sponge extracts Agelas clathrodes, Desmapsamma anchorata and Verongula rigida from a Caribbean Island

por Piron, Julie, Betzi, Stephane, Pastour, Jessica, Restouin, Audrey, Castellano, Rémy, Collette, Yves, Tysklind, Niklas, Smith-Ravin, Juliette, Priam, Fabienne
Publicado 2022

Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies

por Benloucif, Abdennour, Meyer, Damien, Balasse, Laure, Goubard, Armelle, Danner, Lucile, Bouhlel, Ahlem, Castellano, Rémy, Guillet, Benjamin, Chames, Patrick, Kerfelec, Brigitte
Publicado 2023

A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer

por Del Bano, Joanie, Florès-Florès, Rémy, Josselin, Emmanuelle, Goubard, Armelle, Ganier, Laetitia, Castellano, Rémy, Chames, Patrick, Baty, Daniel, Kerfelec, Brigitte
Publicado 2019

Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL)

por Loosveld, Marie, Castellano, Rémy, Gon, Stéphanie, Goubard, Armelle, Crouzet, Thomas, Pouyet, Laurent, Prebet, Thomas, Vey, Norbert, Nadel, Bertrand, Collette, Yves, Payet-Bornet, Dominique
Publicado 2014

Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer

por Karkeni, Esma, Morin, Stéphanie O., Bou Tayeh, Berna, Goubard, Armelle, Josselin, Emmanuelle, Castellano, Rémy, Fauriat, Cyril, Guittard, Geoffrey, Olive, Daniel, Nunès, Jacques A.
Publicado 2019

The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling

por Lopez Almeida, Leonor, Sebbagh, Michael, Bertucci, François, Finetti, Pascal, Wicinski, Julien, Marchetto, Sylvie, Castellano, Rémy, Josselin, Emmanuelle, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Borg, Jean-Paul, Santoni, Marie-Josée
Publicado 2018

A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells

por Berrada, Sara, Martínez-Balsalobre, Elena, Larcher, Lise, Azzoni, Violette, Vasquez, Nadia, Da Costa, Mélanie, Abel, Sébastien, Audoly, Gilles, Lee, Lara, Montersino, Camille, Castellano, Rémy, Combes, Sébastien, Gelot, Camille, Ceccaldi, Raphaël, Guervilly, Jean-Hugues, Soulier, Jean, Lachaud, Christophe
Publicado 2023

Downregulation of stromal syntenin sustains AML development

por Leblanc, Raphael, Ghossoub, Rania, Goubard, Armelle, Castellano, Rémy, Fares, Joanna, Camoin, Luc, Audebert, Stephane, Balzano, Marielle, Bou‐Tayeh, Berna, Fauriat, Cyril, Vey, Norbert, Garciaz, Sylvain, Borg, Jean‐Paul, Collette, Yves, Aurrand‐Lions, Michel, David, Guido, Zimmermann, Pascale
Publicado 2023

Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities

por Le Roy, Aude, Prébet, Thomas, Castellano, Rémy, Goubard, Armelle, Riccardi, Florence, Fauriat, Cyril, Granjeaud, Samuel, Benyamine, Audrey, Castanier, Céline, Orlanducci, Florence, Ben Amara, Amira, Pont, Frédéric, Fournié, Jean-Jacques, Collette, Yves, Mege, Jean-Louis, Vey, Norbert, Olive, Daniel
Publicado 2018

Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity

por Bernard, Pierre-Louis, Delconte, Rebecca, Pastor, Sonia, Laletin, Vladimir, Costa Da Silva, Cathy, Goubard, Armelle, Josselin, Emmanuelle, Castellano, Rémy, Krug, Adrien, Vernerey, Julien, Devillier, Raynier, Olive, Daniel, Verhoeyen, Els, Vivier, Eric, Huntington, Nicholas D, Nunes, Jacques, Guittard, Geoffrey
Publicado 2022

Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer

por Lhoumeau, Anne-Catherine, Martinez, Sébastien, Boher, Jean-Marie, Monges, Geneviève, Castellano, Rémy, Goubard, Armelle, Doremus, Marie, Poizat, Flora, Lelong, Bernard, de Chaisemartin, Cécile, Bardin, Florence, Viens, Patrice, Raoul, Jean-Luc, Prebet, Thomas, Aurrand-Lions, Michel, Borg, Jean-Paul, Gonçalves, Anthony
Publicado 2015

Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

por Lamballe, Fabienne, Ahmad, Fahmida, Vinik, Yaron, Castellanet, Olivier, Daian, Fabrice, Müller, Anna‐Katharina, Köhler, Ulrike A., Bailly, Anne‐Laure, Josselin, Emmanuelle, Castellano, Rémy, Cayrou, Christelle, Charafe‐Jauffret, Emmanuelle, Mills, Gordon B., Géli, Vincent, Borg, Jean‐Paul, Lev, Sima, Maina, Flavio
Publicado 2020

H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines

por Rakotomalala, Andria, Bailleul, Quentin, Savary, Clara, Arcicasa, Mélanie, Hamadou, Maud, Huchedé, Paul, Hochart, Audrey, Restouin, Audrey, Castellano, Remy, Collette, Yves, Dieny, Emma, Vincent, Audrey, Angrand, Pierre-Olivier, Le Bourhis, Xuefen, Leblond, Pierre, Furlan, Alessandro, Castets, Marie, Pasquier, Eddy, Meignan, Samuel
Publicado 2021

A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells

por Arfaoui, Abir, Rioualen, Claire, Azzoni, Violette, Pinna, Guillaume, Finetti, Pascal, Wicinski, Julien, Josselin, Emmanuelle, Macario, Manon, Castellano, Rémy, Léonard‐Stumpf, Candi, Bal, Anthony, Gros, Abigaelle, Lossy, Sylvain, Kharrat, Maher, Collette, Yves, Bertucci, Francois, Birnbaum, Daniel, Douik, Hayet, Bidaut, Ghislain, Charafe‐Jauffret, Emmanuelle, Ginestier, Christophe
Publicado 2019

BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells

por Azzoni, Violette, Wicinski, Julien, Macario, Manon, Castagné, Martin, Finetti, Pascal, Ambrosova, Katerina, Rouault, Célia D., Sergé, Arnaud, Farina, Anne, Agavnian, Emilie, Coslet, Sergiu, Josselin, Emmanuelle, Guille, Arnaud, Adelaide, José, Zacharioudakis, Emmanouil, Castellano, Rémy, Bertucci, Francois, Birnbaum, Daniel, Rodriguez, Raphael, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe
Publicado 2022

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer

por Puvirajesinghe, Tania M., Bertucci, François, Jain, Ashish, Scerbo, Pierluigi, Belotti, Edwige, Audebert, Stéphane, Sebbagh, Michael, Lopez, Marc, Brech, Andreas, Finetti, Pascal, Charafe-Jauffret, Emmanuelle, Chaffanet, Max, Castellano, Rémy, Restouin, Audrey, Marchetto, Sylvie, Collette, Yves, Gonçalvès, Anthony, Macara, Ian, Birnbaum, Daniel, Kodjabachian, Laurent, Johansen, Terje, Borg, Jean-Paul
Publicado 2016

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia

por Saez-Ayala, Magali, Hoffer, Laurent, Abel, Sébastien, Ben Yaala, Khaoula, Sicard, Benoit, Andrieu, Guillaume P., Latiri, Mehdi, Davison, Emma K., Ciufolini, Marco A., Brémond, Paul, Rebuffet, Etienne, Roche, Philippe, Derviaux, Carine, Voisset, Edwige, Montersino, Camille, Castellano, Remy, Collette, Yves, Asnafi, Vahid, Betzi, Stéphane, Dubreuil, Patrice, Combes, Sébastien, Morelli, Xavier
Publicado 2023

CD36 Drives Metastasis and Relapse in Acute Myeloid Leukemia

por Farge, Thomas, Nakhle, Jean, Lagarde, Damien, Cognet, Guillaume, Polley, Nathaniel, Castellano, Rémy, Nicolau, Marie-Laure, Bosc, Claudie, Sabatier, Marie, Sahal, Ambrine, Saland, Estelle, Jeanson, Yannick, Guiraud, Nathan, Boet, Emeline, Bergoglio, Camille, Gotanègre, Mathilde, Mouchel, Pierre-Luc, Stuani, Lucille, Larrue, Clément, Sallese, Marie, De Mas, Véronique, Moro, Cedric, Dray, Cédric, Collette, Yves, Raymond-Letron, Isabelle, Ader, Isabelle, Récher, Christian, Sarry, Jean-Emmanuel, Cabon, Florence, Vergez, François, Carrière, Audrey
Publicado 2023

RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia

por Decroocq, Justine, Birsen, Rudy, Montersino, Camille, Chaskar, Prasad, Mano, Jordi, Poulain, Laury, Friedrich, Chloe, Alary, Anne-Sophie, Guermouche, Helene, Sahal, Ambrine, Fouquet, Guillemette, Gotanègre, Mathilde, Simonetta, Federico, Mouche, Sarah, Gestraud, Pierre, Lescure, Auriane, Del Nery, Elaine, Bosc, Claudie, Grenier, Adrien, Mazed, Fetta, Mondesir, Johanna, Chapuis, Nicolas, Ho, Liza, Boughalem, Aicha, Lelorc’h, Marc, Gobeaux, Camille, Fontenay, Michaela, Recher, Christian, Vey, Norbert, Guillé, Arnaud, Birnbaum, Daniel, Hermine, Olivier, Radford-Weiss, Isabelle, Tsantoulis, Petros, Collette, Yves, Castellano, Rémy, Sarry, Jean-Emmanuel, Pasmant, Eric, Bouscary, Didier, Kosmider, Olivier, Tamburini, Jerome
Publicado 2022