Epigenetic Modifications and Head and Neck Cancer: Implications for Tumor Progression and Resistance to Therapy

por Castilho, Rogerio M., Squarize, Cristiane H., Almeida, Luciana O.
Publicado 2017

Histone Modification on Parathyroid Tumors: A Review of Epigenetics

por Conti de Freitas, Luiz C., Castilho, Rogerio M., Squarize, Cristiane H.
Publicado 2022

Accelerated Wound Healing by mTOR Activation in Genetically Defined Mouse Models

por Squarize, Cristiane H., Castilho, Rogerio M., Bugge, Thomas H., Gutkind, J. Silvio
Publicado 2010

Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells

por Almeida, Luciana O., Guimarães, Douglas M., Squarize, Cristiane H., Castilho, Rogerio M.
Publicado 2016

Inhibition of Histone Deacetylase Impacts Cancer Stem Cells and Induces Epithelial-Mesenchyme Transition of Head and Neck Cancer

por Giudice, Fernanda S., Pinto, Decio S., Nör, Jacques E., Squarize, Cristiane H., Castilho, Rogerio M.
Publicado 2013

Cancer Stem Cells: Powerful Targets to Improve Current Anticancer Therapeutics

por Bighetti-Trevisan, Rayana L., Sousa, Lucas O., Castilho, Rogerio M., Almeida, Luciana O.
Publicado 2019

Rac1 Is Required for Epithelial Stem Cell Function during Dermal and Oral Mucosal Wound Healing but Not for Tissue Homeostasis in Mice

por Castilho, Rogerio M., Squarize, Cristiane H., Leelahavanichkul, Kantima, Zheng, Yi, Bugge, Thomas, Gutkind, J. Silvio
Publicado 2010

Epigenetic Modifications and Accumulation of DNA Double-Strand Breaks in Oral Lichen Planus Lesions Presenting Poor Response to Therapy

por Dillenburg, Caroline S., Martins, Marco A.T., Almeida, Luciana O., Meurer, Luise, Squarize, Cristiane H., Martins, Manoela D., Castilho, Rogerio M.
Publicado 2015

From Tissue Physoxia to Cancer Hypoxia, Cost-Effective Methods to Study Tissue-Specific O(2) Levels in Cellular Biology

por Nascimento-Filho, Carlos H. V., Glinos, Alexandra T., Jang, Yeejin, Goloni-Bertollo, Eny M., Castilho, Rogerio M., Squarize, Cristiane H.
Publicado 2022

PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells

por Zagni, Chiara, Almeida, Luciana O., Balan, Tarek, Martins, Marco T., Rosselli-Murai, Luciana K., Papagerakis, Petros, Castilho, Rogerio M., Squarize, Cristiane H.
Publicado 2017

BMAL1 Modulates Epidermal Healing in a Process Involving the Antioxidative Defense Mechanism

por Silveira, Ericka J. D., Nascimento Filho, Carlos H. V., Yujra, Veronica Q., Webber, Liana P., Castilho, Rogerio M., Squarize, Cristiane H.
Publicado 2020

NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC)()

por Almeida, Luciana O., Abrahao, Aline C., Rosselli-Murai, Luciana K., Giudice, Fernanda S., Zagni, Chiara, Leopoldino, Andreia M., Squarize, Cristiane H., Castilho, Rogerio M.
Publicado 2013

Skin wound healing triggers epigenetic modifications of histone H4

por Nascimento-Filho, Carlos H. V., Silveira, Ericka J. D., Goloni-Bertollo, Eny M., de Souza, Lelia Batista, Squarize, Cristiane H., Castilho, Rogerio M.
Publicado 2020

Periodontal disease affects oral cancer progression in a surrogate animal model for tobacco exposure

por Spuldaro, Tobias R., Wagner, Vivian P., Nör, Felipe, Gaio, Eduardo J., Squarize, Cristiane H., Carrard, Vinicius C., Rösing, Cassiano K., Castilho, Rogerio M.
Publicado 2022

PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells

por Matsumoto, Camila S., Almeida, Luciana O., Guimarães, Douglas M., Martins, Manoela D., Papagerakis, Petros, Papagerakis, Silvana, Leopoldino, Andreia M., Castilho, Rogerio M., Squarize, Cristiane H.
Publicado 2016

Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis

por Wagner, Vivian P., Martins, Marco A.T., Martins, Manoela D., Warner, Kristy A., Webber, Liana P., Squarize, Cristiane H., Nör, Jacques E., Castilho, Rogerio M.
Publicado 2016

Targeting histone deacetylase and NFκB signaling as a novel therapy for Mucoepidermoid Carcinomas

por Wagner, Vivian P., Martins, Manoela D., Martins, Marco A. T., Almeida, Luciana O., Warner, Kristy A., Nör, Jacques E., Squarize, Cristiane H., Castilho, Rogerio M.
Publicado 2018

Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence

por Almeida, Luciana O., Guimarães, Douglas M., Martins, Manoela D., Martins, Marco A.T., Warner, Kristy A., Nör, Jacques E., Castilho, Rogerio M., Squarize, Cristiane H.
Publicado 2017

The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells

por Herzog, Alexandra E., Warner, Kristy A., Zhang, Zhaocheng, Bellile, Emily, Bhagat, Meera A., Castilho, Rogerio M., Wolf, Gregory T., Polverini, Peter J., Pearson, Alexander T., Nör, Jacques E.
Publicado 2021

ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas

por Adams, April, Warner, Kristy, Pearson, Alexander T., Zhang, Zhaocheng, Kim, Hong Sun, Mochizuki, Daiki, Basura, Gregory, Helman, Joseph, Mantesso, Andrea, Castilho, Rogério M., Wicha, Max S., Nör, Jacques E.
Publicado 2015