Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major

por Casu, Carla, Chessa, Roberta, Liu, Alison, Gupta, Ritama, Drakesmith, Hal, Fleming, Robert, Ginzburg, Yelena Z., MacDonald, Brian, Rivella, Stefano
Publicado 2020

Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice

por Casu, Carla, Liu, Alison, De Rosa, Gianluca, Low, Audrey, Suzuki, Aae, Sinha, Sayantani, Ginzburg, Yelena Z., Abrams, Charles, Aghajan, Mariam, Guo, Shuling, Rivella, Stefano
Publicado 2021

Therapeutic Hemoglobin Levels after Gene Transfer in β-Thalassemia Mice and in Hematopoietic Cells of β-Thalassemia and Sickle Cells Disease Patients

por Breda, Laura, Casu, Carla, Gardenghi, Sara, Bianchi, Nicoletta, Cartegni, Luca, Narla, Mohandas, Yazdanbakhsh, Karina, Musso, Marco, Manwani, Deepa, Little, Jane, Gardner, Lawrence B., Kleinert, Dorothy A., Prus, Eugenia, Fibach, Eitan, Grady, Robert W., Giardina, Patricia J., Gambari, Roberto, Rivella, Stefano
Publicado 2012

Macrophages support pathological erythropoiesis in Polycythemia Vera and Beta-Thalassemia

por Ramos, Pedro, Casu, Carla, Gardenghi, Sara, Breda, Laura, Crielaard, Bart J., Guy, Ella, Marongiu, Maria Franca, Gupta, Ritama, Levine, Ross L., Abdel-Wahab, Omar, Ebert, Benjamin L., Van Rooijen, Nico, Ghaffari, Saghi, Grady, Robert W., Giardina, Patricia J., Rivella, Stefano
Publicado 2013

The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry

por Castro-Mollo, Melanie, Gera, Sakshi, Ruiz-Martinez, Marc, Feola, Maria, Gumerova, Anisa, Planoutene, Marina, Clementelli, Cara, Sangkhae, Veena, Casu, Carla, Kim, Se-Min, Ostland, Vaughn, Han, Huiling, Nemeth, Elizabeta, Fleming, Robert, Rivella, Stefano, Lizneva, Daria, Yuen, Tony, Zaidi, Mone, Ginzburg, Yelena
Publicado 2021

2'-O-methoxyethyl splice-switching oligos correct splicing from IVS2-745 β-thalassemia patient cells restoring hemoglobin A production and chain rebalance

por Dong, Alisa, Ghiaccio, Valentina, Motta, Irene, Guo, Shuling, Peralta, Raechel, Freier, Susan M., Watt, Andy, Damle, Sagar, Ikawa, Yasuhiro, Jarocha, Danuta, Chappell, Maxwell, Stephanou, Coralea, Delbini, Paola, Chen, Connie, Christou, Soteroula, Kleanthous, Marina, Smith-Whitley, Kim, Manwani, Deepa, Casu, Carla, Abdulmalik, Osheiza, Cappellini, Maria Domenica, Rivella, Stefano, Breda, Laura
Publicado 2020

Pleckstrin-2 is essential for erythropoiesis in β-thalassemic mice, reducing apoptosis and enhancing enucleation

por Feola, Maria, Zamperone, Andrea, Moskop, Daniel, Chen, Huiyong, Casu, Carla, Lama, Dechen, Di Martino, Julie, Djedaini, Mansour, Papa, Luena, Martinez, Marc Ruiz, Choesang, Tenzin, Bravo-Cordero, Jose Javier, MacKay, Matthew, Zumbo, Paul, Brinkman, Nathan, Abrams, Charles S., Rivella, Stefano, Hattangadi, Shilpa, Mason, Christopher E., Hoffman, Ronald, Ji, Peng, Follenzi, Antonia, Ginzburg, Yelena Z.
Publicado 2021

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

por Pasricha, Sant-Rayn, Lim, Pei Jin, Duarte, Tiago L., Casu, Carla, Oosterhuis, Dorenda, Mleczko-Sanecka, Katarzyna, Suciu, Maria, Da Silva, Ana Rita, Al-Hourani, Kinda, Arezes, João, McHugh, Kirsty, Gooding, Sarah, Frost, Joe N., Wray, Katherine, Santos, Ana, Porto, Graça, Repapi, Emmanouela, Gray, Nicki, Draper, Simon J., Ashley, Neil, Soilleux, Elizabeth, Olinga, Peter, Muckenthaler, Martina U., Hughes, Jim R., Rivella, Stefano, Milne, Thomas A., Armitage, Andrew E., Drakesmith, Hal
Publicado 2017