Factor V Leiden, estrogen, and multimorbidity association with venous thromboembolism in a British-South Asian cohort

por Magavern, Emma F., Smedley, Damian, Caulfield, Mark J.
Publicado 2023

Predicting deleterious nsSNPs: an analysis of sequence and structural attributes

por Dobson, Richard J, Munroe, Patricia B, Caulfield, Mark J, Saqi, Mansoor AS
Publicado 2006

SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort

por Magavern, Emma F., van Heel, David A., Smedley, Damian, Caulfield, Mark J.
Publicado 2023

British South Asian ancestry participants views of pharmacogenomics clinical implementation and research: a thematic analysis

por Magavern, Emma F., Durrani, Faiza, Raza, Mehru, Lerner, Robin, Islam, Mohammed Riadul, Clinch, Megan, Caulfield, Mark J.
Publicado 2023

An online compendium of treatable genetic disorders

por Bick, David, Bick, Sarah L., Dimmock, David P., Fowler, Tom A., Caulfield, Mark J., Scott, Richard H.
Publicado 2020

CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel

por Magavern, Emma F., Jacobs, Benjamin, Warren, Helen, Finocchiaro, Gherardo, Finer, Sarah, van Heel, David A., Smedley, Damian, Caulfield, Mark J.
Publicado 2023

Increased NBCn1 expression, Na(+)/ [Formula: see text] co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension

por Ng, Fu Liang, Boedtkjer, Ebbe, Witkowska, Kate, Ren, Meixia, Zhang, Ruoxin, Tucker, Arthur, Aalkjær, Christian, Caulfield, Mark J., Ye, Shu
Publicado 2017

Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

por Wei, Wei, Schon, Katherine R., Elgar, Greg, Orioli, Andrea, Tanguy, Melanie, Giess, Adam, Tischkowitz, Marc, Caulfield, Mark J., Chinnery, Patrick F.
Publicado 2022

A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity

por Zhang, Ruoxin, Witkowska, Kate, Afonso Guerra-Assunção, José, Ren, Meixia, Ng, Fu Liang, Mauro, Claudio, Tucker, Arthur T., Caulfield, Mark J., Ye, Shu
Publicado 2016

ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon

por Hartmann, Sylvia, Yasmeen, Summaira, Jacobs, Benjamin M., Denaxas, Spiros, Pirmohamed, Munir, Gamazon, Eric R., Caulfield, Mark J., Hemingway, Harry, Pietzner, Maik, Langenberg, Claudia
Publicado 2023

Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D st...

por Raisi-Estabragh, Zahra, McCracken, Celeste, Bethell, Mae S, Cooper, Jackie, Cooper, Cyrus, Caulfield, Mark J, Munroe, Patricia B, Harvey, Nicholas C, Petersen, Steffen E
Publicado 2020

Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

por Siedlinski, Mateusz, Carnevale, Lorenzo, Xu, Xiaoguang, Carnevale, Daniela, Evangelou, Evangelos, Caulfield, Mark J, Maffia, Pasquale, Wardlaw, Joanna, Samani, Nilesh J, Tomaszewski, Maciej, Lembo, Giuseppe, Holmes, Michael V, Guzik, Tomasz J
Publicado 2023

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

por Rapsomaniki, Eleni, Timmis, Adam, George, Julie, Pujades-Rodriguez, Mar, Shah, Anoop D, Denaxas, Spiros, White, Ian R, Caulfield, Mark J, Deanfield, John E, Smeeth, Liam, Williams, Bryan, Hingorani, Aroon, Hemingway, Harry
Publicado 2014

Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protoco...

por Rathod, Krishnaraj S, Jones, Daniel A, Van-Eijl, T J A, Tsang, Hilda, Warren, Helen, Hamshere, Stephen M, Kapil, Vikas, Jain, Ajay K, Deaner, Andrew, Poulter, Neil, Caulfield, Mark J, Mathur, Anthony, Ahluwalia, Amrita
Publicado 2016

White Blood Cells and Blood Pressure: A Mendelian Randomization Study

por Siedlinski, Mateusz, Jozefczuk, Ewelina, Xu, Xiaoguang, Teumer, Alexander, Evangelou, Evangelos, Schnabel, Renate B., Welsh, Paul, Maffia, Pasquale, Erdmann, Jeanette, Tomaszewski, Maciej, Caulfield, Mark J., Sattar, Naveed, Holmes, Michael V., Guzik, Tomasz J.
Publicado 2020

Extracellular volume quantification in isolated hypertension - changes at the detectable limits?

por Treibel, Thomas A., Zemrak, Filip, Sado, Daniel M., Banypersad, Sanjay M., White, Steven K., Maestrini, Viviana, Barison, Andrea, Patel, Vimal, Herrey, Anna S., Davies, Ceri, Caulfield, Mark J., Petersen, Steffen E., Moon, James C.
Publicado 2015

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

por Williams, Bryan, MacDonald, Thomas M, Morant, Steve, Webb, David J, Sever, Peter, McInnes, Gordon, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Salsbury, Jackie, Mackenzie, Isla, Padmanabhan, Sandosh, Brown, Morris J
Publicado 2015

Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

por Wei, Wei, Pagnamenta, Alistair T., Gleadall, Nicholas, Sanchis-Juan, Alba, Stephens, Jonathan, Broxholme, John, Tuna, Salih, Odhams, Christopher A., Fratter, Carl, Turro, Ernest, Caulfield, Mark J., Taylor, Jenny C., Rahman, Shamima, Chinnery, Patrick F.
Publicado 2020

Author Correction: Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

por Wei, Wei, Pagnamenta, Alistair T., Gleadall, Nicholas, Sanchis-Juan, Alba, Stephens, Jonathan, Broxholme, John, Tuna, Salih, Odhams, Christopher A., Fratter, Carl, Turro, Ernest, Caulfield, Mark J., Taylor, Jenny C., Rahman, Shamima, Chinnery, Patrick F.
Publicado 2020

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomise...

por Brown, Morris J, Williams, Bryan, Morant, Steve V, Webb, David J, Caulfield, Mark J, Cruickshank, J Kennedy, Ford, Ian, McInnes, Gordon, Sever, Peter, Salsbury, Jackie, Mackenzie, Isla S, Padmanabhan, Sandosh, MacDonald, Thomas M
Publicado 2016