Editorial: Inhibitors of CDK family: New perspective and rationale for drug combination in preclinical models of solid tumors

por Cavazzoni, Andrea, Palladini, Arianna
Publicado 2023

Role of Cytokines and Other Soluble Factors in Tumor Development: Rationale for New Therapeutic Strategies

por Cavazzoni, Andrea, Digiacomo, Graziana
Publicado 2023

New Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway

por Alfieri, Roberta, Giovannetti, Elisa, Bonelli, Mara, Cavazzoni, Andrea
Publicado 2017

PTEN Alterations as a Potential Mechanism for Tumor Cell Escape from PD-1/PD-L1 Inhibition

por Cretella, Daniele, Digiacomo, Graziana, Giovannetti, Elisa, Cavazzoni, Andrea
Publicado 2019

Biological Hallmarks and New Therapeutic Approaches for the Treatment of PDAC

por Digiacomo, Graziana, Volta, Francesco, Garajova, Ingrid, Balsano, Rita, Cavazzoni, Andrea
Publicado 2021

Hypertonic Stress and Amino Acid Deprivation Both Increase Expression of mRNA for Amino Acid Transport System A

por Alfieri, Roberta R., Bonelli, Mara A., Petronini, Pier Giorgio, Desenzani, Silvia, Cavazzoni, Andrea, Borghetti, Angelo F., Wheeler, Kenneth P.
Publicado 2005

Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells

por Cretella, Daniele, Fumarola, Claudia, Bonelli, Mara, Alfieri, Roberta, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Galetti, Maricla, Generali, Daniele, Petronini, Pier Giorgio
Publicado 2019

It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer

por Garajová, Ingrid, Cavazzoni, Andrea, Verze, Michela, Minari, Roberta, Pedrazzi, Giuseppe, Balsano, Rita, Gelsomino, Fabio, Valle, Raffaele Dalla, Digiacomo, Graziana, Giovannetti, Elisa, Leonardi, Francesco
Publicado 2022

The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells

por Cretella, Daniele, Ravelli, Andrea, Fumarola, Claudia, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Alfieri, Roberta, Biondi, Alessandra, Generali, Daniele, Bonelli, Mara, Petronini, Pier Giorgio
Publicado 2018

Dual Inhibition of CDK4/6 and PI3K/AKT/mTOR Signaling Impairs Energy Metabolism in MPM Cancer Cells

por Bonelli, Mara, Terenziani, Rita, Zoppi, Silvia, Fumarola, Claudia, La Monica, Silvia, Cretella, Daniele, Alfieri, Roberta, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Petronini, Pier Giorgio
Publicado 2020

Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines

por Digiacomo, Graziana, Fumarola, Claudia, La Monica, Silvia, Bonelli, Mara A., Cretella, Daniele, Alfieri, Roberta, Cavazzoni, Andrea, Galetti, Maricla, Bertolini, Patrizia, Missale, Gabriele, Petronini, Pier Giorgio
Publicado 2020

MYC Amplification as a Potential Mechanism of Primary Resistance to Crizotinib in ALK-Rearranged Non-Small Cell Lung Cancer: A Brief Report()()

por Rihawi, Karim, Alfieri, Roberta, Fiorentino, Michelangelo, Fontana, Francesca, Capizzi, Elisa, Cavazzoni, Andrea, Terracciano, Mario, La Monica, Silvia, Ferrarini, Alberto, Buson, Genny, Petronini, Pier Giorgio, Ardizzoni, Andrea
Publicado 2018

Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators

por Volta, Francesco, La Monica, Silvia, Leonetti, Alessandro, Gnetti, Letizia, Bonelli, Mara, Cavazzoni, Andrea, Fumarola, Claudia, Galetti, Maricla, Eltayeb, Kamal, Minari, Roberta, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2023

Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines

por La Monica, Silvia, Cretella, Daniele, Bonelli, Mara, Fumarola, Claudia, Cavazzoni, Andrea, Digiacomo, Graziana, Flammini, Lisa, Barocelli, Elisabetta, Minari, Roberta, Naldi, Nadia, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2017

Efficacy of the CDK4/6 Dual Inhibitor Abemaciclib in EGFR-Mutated NSCLC Cell Lines with Different Resistance Mechanisms to Osimertinib

por La Monica, Silvia, Fumarola, Claudia, Cretella, Daniele, Bonelli, Mara, Minari, Roberta, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Volta, Francesco, Mancini, Maicol, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2020

CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells

por Terenziani, Rita, Galetti, Maricla, La Monica, Silvia, Fumarola, Claudia, Zoppi, Silvia, Alfieri, Roberta, Digiacomo, Graziana, Cavazzoni, Andrea, Cavallo, Delia, Corradi, Massimo, Tiseo, Marcello, Petronini, Pier Giorgio, Bonelli, Mara
Publicado 2022

CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells

por Digiacomo, Graziana, Fumarola, Claudia, La Monica, Silvia, Bonelli, Mara, Cavazzoni, Andrea, Galetti, Maricla, Terenziani, Rita, Eltayeb, Kamal, Volta, Francesco, Zoppi, Silvia, Bertolini, Patrizia, Missale, Gabriele, Alfieri, Roberta, Petronini, Pier Giorgio
Publicado 2022

Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines

por Galetti, Maricla, Petronini, Pier Giorgio, Fumarola, Claudia, Cretella, Daniele, La Monica, Silvia, Bonelli, Mara, Cavazzoni, Andrea, Saccani, Francesca, Caffarra, Cristina, Andreoli, Roberta, Mutti, Antonio, Tiseo, Marcello, Ardizzoni, Andrea, Alfieri, Roberta R.
Publicado 2015

Transforming Growth Factor-Beta Signaling in Cancer-Induced Cachexia: From Molecular Pathways to the Clinics

por Balsano, Rita, Kruize, Zita, Lunardi, Martina, Comandatore, Annalisa, Barone, Mara, Cavazzoni, Andrea, Re Cecconi, Andrea David, Morelli, Luca, Wilmink, Hanneke, Tiseo, Marcello, Garajovà, Ingrid, van Zuylen, Lia, Giovannetti, Elisa, Piccirillo, Rosanna
Publicado 2022

Pemetrexed Enhances Membrane PD-L1 Expression and Potentiates T Cell-Mediated Cytotoxicity by Anti-PD-L1 Antibody Therapy in Non-Small-Cell Lung Cancer

por Cavazzoni, Andrea, Digiacomo, Graziana, Alfieri, Roberta, La Monica, Silvia, Fumarola, Claudia, Galetti, Maricla, Bonelli, Mara, Cretella, Daniele, Barili, Valeria, Zecca, Alessandra, Giovannetti, Elisa, Fiorentino, Michelangelo, Tiseo, Marcello, Petronini, Pier Giorgio, Ardizzoni, Andrea
Publicado 2020