Novel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias

por Lopes, Bruno A., Poubel, Caroline Pires, Teixeira, Cristiane Esteves, Caye-Eude, Aurélie, Cavé, Hélène, Meyer, Claus, Marschalek, Rolf, Boroni, Mariana, Emerenciano, Mariana
Publicado 2022

Case Report: Targeting 2 Antigens as a Promising Strategy in Mixed Phenotype Acute Leukemia: Combination of Blinatumomab With Gemtuzumab Ozogamicin in an Infant With a KMT2A-Rearra...

por Brethon, Benoît, Lainey, Elodie, Caye-Eude, Aurélie, Grain, Audrey, Fenneteau, Odile, Yakouben, Karima, Roupret-Serzec, Julie, Le Mouel, Lou, Cavé, Hélène, Baruchel, André
Publicado 2021

Therapeutic potential of ruxolitinib and ponatinib in patients with EPOR-rearranged Philadelphia chromosome-like acute lymphoblastic leukemia

por Niswander, Lisa M., Loftus, Joseph P, Lainey, Élodie, Caye-Eude, Aurélie, Pondrom, Morgane, Hottman, David A., Iacobucci, Ilaria, Mullighan, Charles G., Jain, Nitin, Konopleva, Marina, Cavé, Hélène, Baruchel, André, Rohrlich, Pierre S., Tasian, Sarah K.
Publicado 2021

The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome

por Külp, Marius, Larghero, Patrizia, Alten, Julia, Cario, Gunnar, Eckert, Cornelia, Caye-Eude, Aurélie, Cavé, Hélène, Schmachtel, Tessa, Bardini, Michela, Cazzaniga, Giovanni, De Lorenzo, Paola, Valsecchi, Maria Grazia, Bonig, Halvard, Meyer, Claus, Rieger, Michael A., Marschalek, Rolf
Publicado 2023

The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t(4;11) acute lymphoblastic leukemia

por Külp, Marius, Siemund, Anna Lena, Larghero, Patrizia, Dietz, Alissa, Alten, Julia, Cario, Gunnar, Eckert, Cornelia, Caye-Eude, Aurélie, Cavé, Hélène, Bardini, Michela, Cazzaniga, Giovanni, De Lorenzo, Paola, Valsecchi, Maria Grazia, Diehl, Laura, Bonig, Halvard, Meyer, Claus, Marschalek, Rolf
Publicado 2022

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

por Unda, Brianna K., Chalil, Leon, Yoon, Sehyoun, Kilpatrick, Savannah, Irwin, Courtney, Xing, Sansi, Murtaza, Nadeem, Cheng, Anran, Brown, Chad, Afonso, Alexandria, McCready, Elizabeth, Ronen, Gabriel M., Howe, Jennifer, Caye-Eude, Aurélie, Verloes, Alain, Doble, Brad W., Faivre, Laurence, Vitobello, Antonio, Scherer, Stephen W., Lu, Yu, Penzes, Peter, Singh, Karun K.
Publicado 2023

KMT2A-CBL rearrangements in acute leukemias: clinical characteristics and genetic breakpoints

por Bataller, Alex, Guijarro, Francesca, Caye-Eude, Aurélie, Strullu, Marion, Sterin, Arthur, Molina, Oscar, Chevallier, Patrice, Zaliova, Marketa, Zuna, Jan, Mozas, Pablo, Magnano, Laura, Grardel, Nathalie, Cornillet-Lefebvre, Pascale, Fu, Jen-Fen, Shih, Lee-Yung, Boneva, Temenuzhka, Nacheva, Elisabeth, Beà, Silvia, López-Guerra, Mònica, Bueno, Clara, Menéndez, Pablo, Esteve, Jordi, Larghero, Patrizia, Meyer, Claus, Marschalek, Rolf
Publicado 2021

B-ALL With t(5;14)(q31;q32); IGH-IL3 Rearrangement and Eosinophilia: A Comprehensive Analysis of a Peculiar IGH-Rearranged B-ALL

por Fournier, Benjamin, Balducci, Estelle, Duployez, Nicolas, Clappier, Emmanuelle, Cuccuini, Wendy, Arfeuille, Chloé, Caye-Eude, Aurélie, Delabesse, Eric, Bottollier-Lemallaz Colomb, Elodie, Nebral, Karin, Chrétien, Marie-Lorraine, Derrieux, Coralie, Cabannes-Hamy, Aurélie, Dumezy, Florent, Etancelin, Pascaline, Fenneteau, Odile, Frayfer, Jamile, Gourmel, Antoine, Loosveld, Marie, Michel, Gérard, Nadal, Nathalie, Penther, Dominique, Tigaud, Isabelle, Fournier, Elise, Reismüller, Bettina, Attarbaschi, Andishe, Lafage-Pochitaloff, Marina, Baruchel, André
Publicado 2019

P315: TP53 ALTERATIONS AND MRD REFINE PROGNOSIS OF ADULT KMT2A-REARRANGED B-ALL

por Kim, Rathana, Bergugnat, Hugo, Pasquier, Florence, Raffoux, Emmanuel, Larcher, Lise, Passet, Marie, Pastoret, Cedric, Nathalie, Grardel, Asnafi, Vahid, Delabesse, Eric, Caye-Eude, Aurélie, Meyer, Claus, Masrschalek, Rolf, Thiebaut-Bertrand, Anne, Balsat, Marie, Escoffre, Martine, Blum, Sabine, Baumann, Michael, Banos, Anne, Straetmans, Nicole, Pilar Gallego Hernanz, Maria, Chalandon, Yves, Graux, Carlos, Leguay, Thibaut, Hunault, Mathilde, Huguet, Françoise, Lhéritier, Véronique, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle
Publicado 2023

Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions

por Meyer, Claus, Lopes, Bruno A., Caye-Eude, Aurélie, Cavé, Hélène, Arfeuille, Chloé, Cuccuini, Wendy, Sutton, Rosemary, Venn, Nicola C., Oh, Seung Hwan, Tsaur, Grigory, Escherich, Gabriele, Feuchtinger, Tobias, Kosasih, Hansen J., Khaw, Seong L., Ekert, Paul G., Pombo-de-Oliveira, Maria S., Bidet, Audrey, Djahanschiri, Bardya, Ebersberger, Ingo, Zaliova, Marketa, Zuna, Jan, Zermanova, Zuzana, Juvonen, Vesa, Grümayer, Renate Panzer, Fazio, Grazia, Cazzaniga, Gianni, Larghero, Patrizia, Emerenciano, Mariana, Marschalek, Rolf
Publicado 2019

Targeted High-throughput Sequencing for Hematological Malignancies: A GBMHM Survey of Practice and Cost Evaluation in France

por Darlington, Meryl, Sujobert, Pierre, Kosmider, Olivier, Luque Paz, Damien, Kaltenbach, Sophie, Figeac, Martin, Hayette, Sandrine, Mezaour, Nadia, Coquerelle, Séverine, Alary, Anne-Sophie, Bidet, Audrey, Le Bris, Yannick, Delabesse, Eric, Davi, Frédéric, Preudhomme, Claude, Durand-Zaleski, Isabelle, Macintyre, Elizabeth, Alame, Mélissa, Baran-Marzak, Fanny, Berger, Marc G., Bories, Dominique, Caye-Eude, Aurélie, Cayuela, Jean-Michel, Cornillet-Lefebvre, Pascale, Delhommeau, François, Estienne-Felix, Marie-Hélène, Etancelin, Pascaline, Flandrin-Gresta, Pascale, Lippert, Eric, Marzac, Christophe, Miguet, Laurent, Pastoret, Cédric, Raynaud, Sophie, Rizzo, David
Publicado 2023