Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase

por Cea-Rama, Isabel, Coscolín, Cristina, Katsonis, Panagiotis, Bargiela, Rafael, Golyshin, Peter N., Lichtarge, Olivier, Ferrer, Manuel, Sanz-Aparicio, Julia
Publicado 2021

Increased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates

por Goris, Marianne, Cea-Rama, Isabel, Puntervoll, Pål, Ree, Rasmus, Almendral, David, Sanz-Aparicio, Julia, Ferrer, Manuel, Bjerga, Gro Elin Kjæreng
Publicado 2023

The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome

por Distaso, Marco, Cea-Rama, Isabel, Coscolín, Cristina, Chernikova, Tatyana N., Tran, Hai, Ferrer, Manuel, Sanz-Aparicio, Julia, Golyshin, Peter N.
Publicado 2023

Crystal structure of a family VIII β‐lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope

por Cea‐Rama, Isabel, Coscolín, Cristina, Gonzalez‐Alfonso, Jose L., Raj, Jog, Vasiljević, Marko, Plou, Francisco J., Ferrer, Manuel, Sanz‐Aparicio, Julia
Publicado 2022

The bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry

por Fernandez-Lopez, Laura, Sanchez-Carrillo, Sergio, García-Moyano, Antonio, Borchert, Erik, Almendral, David, Alonso, Sandra, Cea-Rama, Isabel, Miguez, Noa, Larsen, Øivind, Werner, Johannes, Makarova, Kira S., Plou, Francisco J., Dahlgren, Thomas G., Sanz-Aparicio, Julia, Hentschel, Ute, Bjerga, Gro Elin Kjæreng, Ferrer, Manuel
Publicado 2021