Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo

por Chakrabarty, Paramita, Herring, Amanda, Ceballos-Diaz, Carolina, Das, Pritam, Golde, Todd E
Publicado 2011

Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice

por Chu, Jin, Giannopoulos, Phillip F, Ceballos-Diaz, Carolina, Golde, Todd E, Pratico, Domenico
Publicado 2012

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition

por Chakrabarty, Paramita, Tianbai, Li, Herring, Amanda, Ceballos-Diaz, Carolina, Das, Pritam, Golde, Todd E
Publicado 2012

Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors

por Ran, Yong, Ladd, Gabriela Z., Ceballos-Diaz, Carolina, Jung, Joo In, Greenbaum, Doron, Felsenstein, Kevin M., Golde, Todd E.
Publicado 2015

Conformational templating of α-synuclein aggregates in neuronal-glial cultures

por Sacino, Amanda N, Thomas, Michael A, Ceballos-Diaz, Carolina, Cruz, Pedro E, Rosario, Awilda M, Lewis, Jada, Giasson, Benoit I, Golde, Todd E
Publicado 2013

Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice

por Rutherford, Nicola J., Sacino, Amanda N., Brooks, Mieu, Ceballos-Diaz, Carolina, Ladd, Thomas B., Howard, Jasie K., Golde, Todd E., Giasson, Benoit I.
Publicado 2015

Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis

por Verbeeck, Christophe, Deng, Qiudong, DeJesus-Hernandez, Mariely, Taylor, Georgia, Ceballos-Diaz, Carolina, Kocerha, Jannet, Golde, Todd, Das, Pritam, Rademakers, Rosa, Dickson, Dennis W, Kukar, Thomas
Publicado 2012

Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes

por Goodwin, Marshall S., Sinyavskaya, Olga, Burg, Franklin, O’Neal, Veronica, Ceballos-Diaz, Carolina, Cruz, Pedro E., Lewis, Jada, Giasson, Benoit I., Davies, Peter, Golde, Todd E., Levites, Yona
Publicado 2021

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

por Chakrabarty, Paramita, Rosario, Awilda, Cruz, Pedro, Siemienski, Zoe, Ceballos-Diaz, Carolina, Crosby, Keith, Jansen, Karen, Borchelt, David R., Kim, Ji-Yoen, Jankowsky, Joanna L., Golde, Todd E., Levites, Yona
Publicado 2013

Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice

por Ceballos-Diaz, Carolina, Rosario, Awilda M., Park, Hyo-Jin, Chakrabarty, Paramita, Sacino, Amanda, Cruz, Pedro E., Siemienski, Zoe, Lara, Nicolas, Moran, Corey, Ravelo, Natalia, Golde, Todd E., McFarland, Nikolaus R.
Publicado 2015

Microglia-specific targeting by novel capsid-modified AAV6 vectors

por Rosario, Awilda M, Cruz, Pedro E, Ceballos-Diaz, Carolina, Strickland, Michael R, Siemienski, Zoe, Pardo, Meghan, Schob, Keri-Lyn, Li, Andrew, Aslanidi, George V, Srivastava, Arun, Golde, Todd E, Chakrabarty, Paramita
Publicado 2016

Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

por De Mena, Lorena, Smith, Michael A., Martin, Jason, Dunton, Katie L., Ceballos-Diaz, Carolina, Jansen-West, Karen R., Cruz, Pedro E., Dillon, Kristy D., Rincon-Limas, Diego E., Golde, Todd E., Moore, Brenda D., Levites, Yona
Publicado 2020

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator

por Jung, Joo In, Price, Ashleigh R., Ladd, Thomas B., Ran, Yong, Park, Hyo-Jin, Ceballos-Diaz, Carolina, Smithson, Lisa A., Hochhaus, Günther, Tang, Yufei, Akula, Rajender, Ba, Saritha, Koo, Edward H., Shapiro, Gideon, Felsenstein, Kevin M., Golde, Todd E.
Publicado 2015

rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies

por Croft, Cara L., Cruz, Pedro E., Ryu, Daniel H., Ceballos-Diaz, Carolina, Strang, Kevin H., Woody, Brittany M., Lin, Wen-Lang, Deture, Michael, Rodríguez-Lebrón, Edgardo, Dickson, Dennis W., Chakrabarty, Paramita, Levites, Yona, Giasson, Benoit I., Golde, Todd E.
Publicado 2019

Il-10 signaling reduces survival in mouse models of synucleinopathy

por Cockey, Samuel G., McFarland, Karen N., Koller, Emily J., Brooks, Mieu M. T., Gonzalez De La Cruz, Elsa, Cruz, Pedro E., Ceballos-Diaz, Carolina, Rosario, Awilda M., Levites, Yona R., Borchelt, David R., Golde, Todd E., Giasson, Benoit I., Chakrabarty, Paramita
Publicado 2021

Short Aβ peptides attenuate Aβ42 toxicity in vivo

por Moore, Brenda D., Martin, Jason, de Mena, Lorena, Sanchez, Jonatan, Cruz, Pedro E., Ceballos-Diaz, Carolina, Ladd, Thomas B., Ran, Yong, Levites, Yona, Kukar, Thomas L., Kurian, Justin J., McKenna, Robert, Koo, Edward H., Borchelt, David R., Janus, Christopher, Rincon-Limas, Diego, Fernandez-Funez, Pedro, Golde, Todd E.
Publicado 2018

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

por Goodwin, Marshall S., Croft, Cara L., Futch, Hunter S., Ryu, Daniel, Ceballos-Diaz, Carolina, Liu, Xuefei, Paterno, Giavanna, Mejia, Catalina, Deng, Doris, Menezes, Kimberly, Londono, Laura, Arjona, Kefren, Parianos, Mary, Truong, Van, Rostonics, Eva, Hernandez, Amanda, Boye, Sanford L., Boye, Shannon E., Levites, Yona, Cruz, Pedro E., Golde, Todd E.
Publicado 2020

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease

por Chakrabarty, Paramita, Li, Andrew, Ladd, Thomas B., Strickland, Michael R., Koller, Emily J., Burgess, Jeremy D., Funk, Cory C., Cruz, Pedro E., Allen, Mariet, Yaroshenko, Mariya, Wang, Xue, Younkin, Curtis, Reddy, Joseph, Lohrer, Benjamin, Mehrke, Leonie, Moore, Brenda D., Liu, Xuefei, Ceballos-Diaz, Carolina, Rosario, Awilda M., Medway, Christopher, Janus, Christopher, Li, Hong-Dong, Dickson, Dennis W., Giasson, Benoit I., Price, Nathan D., Younkin, Steven G., Ertekin-Taner, Nilüfer, Golde, Todd E.
Publicado 2018