Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

por Koszela, Joanna, Pham, Nhan T., Evans, David, Mann, Stefan, Perez-Pi, Irene, Shave, Steven, Ceccarelli, Derek F. J., Sicheri, Frank, Tyers, Mike, Auer, Manfred
Publicado 2018

Dissecting BAR Domain Function in the Yeast Amphiphysins Rvs161 and Rvs167 during Endocytosis

por Youn, Ji-Young, Friesen, Helena, Kishimoto, Takuma, Henne, William M., Kurat, Christoph F., Ye, Wei, Ceccarelli, Derek F., Sicheri, Frank, Kohlwein, Sepp D., McMahon, Harvey T., Andrews, Brenda J.
Publicado 2010

E2 enzyme inhibition by stabilization of a low affinity interface with ubiquitin

por Huang, Hao, Ceccarelli, Derek F, Orlicky, Stephen, St-Cyr, Daniel J., Ziemba, Amy, Garg, Pankaj, Plamondon, Serge, Auer, Manfred, Sidhu, Sachdev, Marinier, Anne, Kleiger, Gary, Tyers, Mike, Sicheri, Frank
Publicado 2013

The linear ubiquitin-specific deubiquitinase Gumby/Fam105b regulates angiogenesis

por Rivkin, Elena, Almeida, Stephanie M., Ceccarelli, Derek F., Juang, Yu-Chi, MacLean, Teresa A., Srikumar, Tharan, Huang, Hao, Dunham, Wade H., Fukumura, Ryutaro, Xie, Gang, Gondo, Yoichi, Raught, Brian, Gingras, Anne-Claude, Sicheri, Frank, Cordes, Sabine P.
Publicado 2013

Higher -Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function

por Zeqiraj, Elton, Tian, Lei, Piggott, Christopher A., Pillon, Monica C., Duffy, Nicole M., Ceccarelli, Derek F., Keszei, Alexander F. A., Lorenzen, Kristina, Kurinov, Igor, Orlicky, Stephen, Gish, Gerald D., Heck, Albert J.R., Guarné, Alba, Greenberg, Roger A., Sicheri, Frank
Publicado 2015

A substrate binding model for the KEOPS tRNA modifying complex

por Beenstock, Jonah, Ona, Samara Mishelle, Porat, Jennifer, Orlicky, Stephen, Wan, Leo C. K., Ceccarelli, Derek F., Maisonneuve, Pierre, Szilard, Rachel K., Yin, Zhe, Setiaputra, Dheva, Mao, Daniel Y. L., Khan, Morgan, Raval, Shaunak, Schriemer, David C., Bayfield, Mark A., Durocher, Daniel, Sicheri, Frank
Publicado 2020

Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity

por Huang, Hao, Zeqiraj, Elton, Dong, Beihua, Jha, Babal Kant, Duffy, Nicole M., Orlicky, Stephen, Thevakumaran, Neroshan, Talukdar, Manisha, Pillon, Monica C., Ceccarelli, Derek F., Wan, Leo C.K., Juang, Yu-Chi, Mao, Daniel Y.L., Gaughan, Christina, Brinton, Margo A., Perelygin, Andrey A., Kourinov, Igor, Guarné, Alba, Silverman, Robert H., Sicheri, Frank
Publicado 2014

Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4

por Chana, Chetan K., Maisonneuve, Pierre, Posternak, Ganna, Grinberg, Nicolas G.A., Poirson, Juline, Ona, Samara M., Ceccarelli, Derek F., Mader, Pavel, St-Cyr, Daniel J., Pau, Victor, Kurinov, Igor, Tang, Xiaojing, Deng, Dongjing, Cui, Weiren, Su, Wenji, Kuai, Letian, Soll, Richard, Tyers, Mike, Röst, Hannes L., Batey, Robert A., Taipale, Mikko, Gingras, Anne-Claude, Sicheri, Frank
Publicado 2022