Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)

por Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent JS De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas DY, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas DP, Tautz, Lutz
Publicado 2021

Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo

por Pache, Lars, Marsden, Matthew D., Teriete, Peter, Portillo, Alex J., Heimann, Dominik, Kim, Jocelyn T., Soliman, Mohamed S.A., Dimapasoc, Melanie, Carmona, Camille, Celeridad, Maria, Spivak, Adam M., Planelles, Vicente, Cosford, Nicholas D.P., Zack, Jerome A., Chanda, Sumit K.
Publicado 2020

Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells

por Raveendra-Panickar, Dhanya, Finlay, Darren, Layng, Fabiana Izidro, Lambert, Lester J., Celeridad, Maria, Zhao, Ming, Barbosa, Karina, De Backer, Laurent J.S., Kwong, Elizabeth, Gosalia, Palak, Rodiles, Socorro, Holleran, John, Ardecky, Robert, Grotegut, Stefan, Olson, Steven, Hutchinson, John H., Pasquale, Elena B., Vuori, Kristiina, Deshpande, Aniruddha J., Cosford, Nicholas D.P., Tautz, Lutz
Publicado 2021

Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo

por Yue, Peibin, Zhu, Yinsong, Brotherton-Pleiss, Christine, Fu, Wenzhen, Verma, Nagendra, Chen, Jasmine, Nakamura, Kayo, Chen, Weiliang, Chen, Yue, Alonso-Valenteen, Felix, Mikhael, Simoun, Medina-Kauwe, Lali, Kershaw, Kathleen M., Celeridad, Maria, Pan, Songqin, Limpert, Allison S., Sheffler, Douglas J., Cosford, Nicholas D. P., Shiao, Stephen L., Tius, Marcus A., Lopez-Tapia, Francisco, Turkson, James
Publicado 2022

A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation

por Ferguson, Gregory D., Delgado, Mercedes, Plantevin-Krenitsky, Veronique, Jensen-Pergakes, Kristen, Bates, R. J., Torres, Sanaa, Celeridad, Maria, Brown, Heather, Burnett, Kelven, Nadolny, Lisa, Tehrani, Lida, Packard, Garrick, Pagarigan, Barbra, Haelewyn, Jason, Nguyen, Trish, Xu, Li, Tang, Yang, Hickman, Matthew, Baculi, Frans, Pierce, Steven, Miyazawa, Keiji, Jackson, Pilgrim, Chamberlain, Philip, LeBrun, Laurie, Xie, Weilin, Bennett, Brydon, Blease, Kate
Publicado 2016