Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic

por Cerrato, Aniello, Morra, Francesco, Celetti, Angela
Publicado 2016

The rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer

por Cerrato, Aniello, Visconti, Roberta, Celetti, Angela
Publicado 2018

Mono(ADP-ribosyl)ation Enzymes and NAD(+) Metabolism: A Focus on Diseases and Therapeutic Perspectives

por Poltronieri, Palmiro, Celetti, Angela, Palazzo, Luca
Publicado 2021

A xCT role in tumour-associated ferroptosis shed light on novel therapeutic options

por Criscuolo, Daniela, Morra, Francesco, Celetti, Angela
Publicado 2022

The between Now and Then of Lung Cancer Chemotherapy and Immunotherapy

por Visconti, Roberta, Morra, Francesco, Guggino, Gianluca, Celetti, Angela
Publicado 2017

NSCLC Mutated Isoforms of CCDC6 Affect the Intracellular Distribution of the Wild Type Protein Promoting Cisplatinum Resistance and PARP Inhibitors Sensitivity in Lung Cancer Cells

por Cerrato, Aniello, Morra, Francesco, Di Domenico, Imma, Celetti, Angela
Publicado 2019

Identification of Novel Biomarkers of Homologous Recombination Defect in DNA Repair to Predict Sensitivity of Prostate Cancer Cells to PARP-Inhibitors

por Criscuolo, Daniela, Morra, Francesco, Giannella, Riccardo, Cerrato, Aniello, Celetti, Angela
Publicado 2019

Loss of CCDC6, the First Identified RET Partner Gene, Affects pH2AX S139 Levels and Accelerates Mitotic Entry upon DNA Damage

por Merolla, Francesco, Luise, Chiara, Muller, Mark T., Pacelli, Roberto, Fusco, Alfredo, Celetti, Angela
Publicado 2012

New combinatorial strategies to improve the PARP inhibitors efficacy in the urothelial bladder Cancer treatment

por Criscuolo, Daniela, Morra, Francesco, Giannella, Riccardo, Visconti, Roberta, Cerrato, Aniello, Celetti, Angela
Publicado 2019

Identification of Sumoylation Sites in CCDC6, the First Identified RET Partner Gene in Papillary Thyroid Carcinoma, Uncovers a Mode of Regulating CCDC6 Function on CREB1 Transcript...

por Luise, Chiara, Merolla, Francesco, Leone, Vincenza, Paladino, Simona, Sarnataro, Daniela, Fusco, Alfredo, Celetti, Angela
Publicado 2012

The tumour suppressor CCDC6 is involved in ROS tolerance and neoplastic transformation by evading ferroptosis

por Morra, Francesco, Merolla, Francesco, Zito Marino, Federica, Catalano, Rosaria, Franco, Renato, Chieffi, Paolo, Celetti, Angela
Publicado 2021

The combined effect of USP7 inhibitors and PARP inhibitors in hormone-sensitive and castration-resistant prostate cancer cells

por Morra, Francesco, Merolla, Francesco, Napolitano, Virginia, Ilardi, Gennaro, Miro, Caterina, Paladino, Simona, Staibano, Stefania, Cerrato, Aniello, Celetti, Angela
Publicado 2017

CCDC6 and USP7 expression levels suggest novel treatment options in high-grade urothelial bladder cancer

por Morra, Francesco, Merolla, Francesco, Criscuolo, Daniela, Insabato, Luigi, Giannella, Riccardo, Ilardi, Gennaro, Cerrato, Aniello, Visconti, Roberta, Staibano, Stefania, Celetti, Angela
Publicado 2019

Epigenetics of oral and oropharyngeal cancers (Review)

por Russo, Daniela, Merolla, Francesco, Varricchio, Silvia, Salzano, Giovanni, Zarrilli, Giovanni, Mascolo, Massimo, Strazzullo, Viviana, Crescenzo, Rosa Maria Di, Celetti, Angela, Ilardi, Gennaro
Publicado 2020

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

por Rossi, Matteo, Colecchia, David, Ilardi, Gennaro, Acunzo, Mario, Nigita, Giovanni, Sasdelli, Federica, Celetti, Angela, Strambi, Angela, Staibano, Stefania, Croce, Carlo Maria, Chiariello, Mario
Publicado 2016

Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors

por Staibano, Stefania, Ilardi, Gennaro, Leone, Vincenza, Luise, Chiara, Merolla, Francesco, Esposito, Francesco, Morra, Francesco, Siano, Maria, Franco, Renato, Fusco, Alfredo, Chieffi, Paolo, Celetti, Angela
Publicado 2013

CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC

por Morra, Francesco, Merolla, Francesco, Picardi, Ida, Russo, Daniela, Ilardi, Gennaro, Varricchio, Silvia, Liotti, Federica, Pacelli, Roberto, Palazzo, Luca, Mascolo, Massimo, Celetti, Angela, Staibano, Stefania
Publicado 2019

Retraction Note: Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors

por Staibano, Stefania, Ilardi, Gennaro, Leone, Vincenza, Luise, Chiara, Merolla, Francesco, Esposito, Francesco, Morra, Francesco, Siano, Maria, Franco, Renato, Fusco, Alfredo, Chieffi, Paolo, Celetti, Angela
Publicado 2021

Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity

por Leone, Vincenza, Langella, Concetta, Esposito, Francesco, Arra, Claudio, Palma, Giuseppe, Rea, Domenica, Paciello, Orlando, Merolla, Francesco, De Biase, Davide, Papparella, Serenella, Celetti, Angela, Fusco, Alfredo
Publicado 2015

Neuropilin-1 Expression Associates with Poor Prognosis in HNSCC and Elicits EGFR Activation upon CDDP-Induced Cytotoxic Stress

por Napolitano, Virginia, Russo, Daniela, Morra, Francesco, Merolla, Francesco, Varricchio, Silvia, Ilardi, Gennaro, Di Crescenzo, Rosa Maria, Martino, Francesco, Mascolo, Massimo, Celetti, Angela, Tamagnone, Luca, Staibano, Stefania
Publicado 2021